| Structure of class B GPCR corticotropin-releasing factor receptor 1 K Hollenstein, J Kean, A Bortolato, RKY Cheng, AS Doré, A Jazayeri, ... Nature 499 (7459), 438-443, 2013 | 501 | 2013 |
| Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons T Weinert, N Olieric, R Cheng, S Brünle, D James, D Ozerov, D Gashi, ... Nature communications 8 (1), 542, 2017 | 245 | 2017 |
| Structural insight into allosteric modulation of protease-activated receptor 2 RKY Cheng, C Fiez-Vandal, O Schlenker, K Edman, B Aggeler, DG Brown, ... Nature 545 (7652), 112-115, 2017 | 240 | 2017 |
| Structures of human A1 and A2A adenosine receptors with xanthines reveal determinants of selectivity RKY Cheng, E Segala, N Robertson, F Deflorian, AS Doré, JC Errey, ... Structure 25 (8), 1275-1285. e4, 2017 | 212 | 2017 |
| Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength E Segala, D Guo, RKY Cheng, A Bortolato, F Deflorian, AS Doré, JC Errey, ... Journal of medicinal chemistry 59 (13), 6470-6479, 2016 | 184 | 2016 |
| Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals P Rucktooa, RKY Cheng, E Segala, T Geng, JC Errey, GA Brown, ... Scientific Reports 8 (1), 41, 2018 | 93 | 2018 |
| Discovery and structure–activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington’s disease ME Prime, OA Andersen, JJ Barker, MA Brooks, RKY Cheng, ... Journal of medicinal chemistry 55 (3), 1021-1046, 2012 | 85 | 2012 |
| Fragment‐based identification of Hsp90 inhibitors JJ Barker, O Barker, R Boggio, V Chauhan, RKY Cheng, V Corden, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (6), 963-966, 2009 | 71 | 2009 |
| Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity A Borodovsky, CM Barbon, Y Wang, M Ye, L Prickett, D Chandra, J Shaw, ... Journal for Immunotherapy of Cancer 8 (2), 2020 | 69 | 2020 |
| Towards an optimal sample delivery method for serial crystallography at XFEL RKY Cheng Crystals 10 (3), 215, 2020 | 48 | 2020 |
| Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists AK Apel, RKY Cheng, CS Tautermann, M Brauchle, CY Huang, A Pautsch, ... Structure 27 (3), 427-438. e5, 2019 | 42 | 2019 |
| Fragment-based discovery of 7-azabenzimidazoles as potent, highly selective, and orally active CDK4/6 inhibitors YS Cho, H Angove, C Brain, CHT Chen, H Cheng, R Cheng, R Chopra, ... ACS Medicinal Chemistry Letters 3 (6), 445-449, 2012 | 42 | 2012 |
| Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB MF Mesleh, JB Cross, J Zhang, J Kahmann, OA Andersen, J Barker, ... Bioorganic & Medicinal Chemistry Letters 26 (4), 1314-1318, 2016 | 38 | 2016 |
| Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A2A Receptor T Amelia, JPD van Veldhoven, M Falsini, R Liu, LH Heitman, ... Journal of Medicinal Chemistry 64 (7), 3827-3842, 2021 | 34 | 2021 |
| Advances in long-wavelength native phasing at X-ray free-electron lasers K Nass, R Cheng, L Vera, A Mozzanica, S Redford, D Ozerov, S Basu, ... IUCrJ 7 (6), 965-975, 2020 | 28 | 2020 |
| Decoding corticotropin-releasing factor receptor type 1 crystal structures A S Dore, A Bortolato, K Hollenstein, R KY Cheng, R J Read, F H Marshall Current Molecular Pharmacology 10 (4), 334-344, 2017 | 28 | 2017 |
| High‐resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand R Cheng, B Felicetti, S Palan, I Toogood‐Johnson, C Scheich, J Barker, ... Protein Science 19 (1), 168-173, 2010 | 28 | 2010 |
| X-ray free electron laser: opportunities for drug discovery RKY Cheng, R Abela, M Hennig Essays in Biochemistry 61 (5), 529-542, 2017 | 22 | 2017 |
| HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1, 1-dioxo-2H-[1, 2, 4] benzothiadiazin-3-yl) azolo [1, 5-a] pyridine and azolo [1, 5-a] pyrimidine … G Wang, H Lei, X Wang, D Das, J Hong, CH Mackinnon, TS Coulter, ... Bioorganic & medicinal chemistry letters 19 (15), 4480-4483, 2009 | 22 | 2009 |
| The structure of RK Cheng, L Crawley, M Wood, J Barker, B Felicetti, M Whittaker E. coli, 2002 | 18 | 2002 |
