Byron Caughey
Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders
B Caughey, PT Lansbury Jr
Annual review of neuroscience 26, 267, 2003
Cell-free formation of protease-resistant prion protein
DA Kocisko, JH Come, SA Priola, B Chesebro, GJ Raymond, PT Lansbury, ...
Nature 370 (6489), 471-474, 1994
The most infectious prion protein particles
JR Silveira, GJ Raymond, AG Hughson, RE Race, VL Sim, SF Hayes, ...
Nature 437 (7056), 257-261, 2005
Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy
BW Caughey, A Dong, KS Bhat, D Ernst, SF Hayes, WS Caughey
Biochemistry 30 (31), 7672-7680, 1991
The scrapie-associated form of PrP is made from a cell surface precursor that is both protease-and phospholipase-sensitive.
B Caughey, GJ Raymond
Journal of Biological Chemistry 266 (27), 18217-18223, 1991
Anchorless prion protein results in infectious amyloid disease without clinical scrapie
B Chesebro, M Trifilo, R Race, K Meade-White, C Teng, R LaCasse, ...
Science 308 (5727), 1435-1439, 2005
Non-genetic propagation of strain-specific properties of scrapie prion protein
RA Bessen, DA Kocisko, GJ Raymond, S Nandan, PT Lansbury, ...
Nature 375 (6533), 698-700, 1995
N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease (s): implications regarding the site of conversion of PrP to the protease-resistant state
B Caughey, GJ Raymond, D Ernst, RE Race
Journal of virology 65 (12), 6597-6603, 1991
Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells
B Caughey, GJ Raymond
Journal of virology 67 (2), 643-650, 1993
Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier.
DA Kocisko, SA Priola, GJ Raymond, B Chesebro, PT Lansbury Jr, ...
Proceedings of the National Academy of Sciences 92 (9), 3923-3927, 1995
Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays
JM Wilham, CD Orrú, RA Bessen, R Atarashi, K Sano, B Race, ...
PLoS pathogens 6 (12), e1001217, 2010
Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells
B Caughey, RE Race, D Ernst, MJ Buchmeier, B Chesebro
Journal of virology 63 (1), 175-181, 1989
Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation
K Doh-Ura, T Iwaki, B Caughey
Journal of virology 74 (10), 4894-4897, 2000
Strain-dependent differences in β-sheet conformations of abnormal prion protein
B Caughey, GJ Raymond, RA Bessen
Journal of Biological Chemistry 273 (48), 32230-32235, 1998
Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein
R Atarashi, RA Moore, VL Sim, AG Hughson, DW Dorward, HA Onwubiko, ...
Nature methods 4 (8), 645-650, 2007
Real time quaking‐induced conversion analysis of cerebrospinal fluid in sporadic Creutzfeldt–Jakob disease
LI McGuire, AH Peden, CD Orrú, JM Wilham, NE Appleford, G Mallinson, ...
Annals of neurology 72 (2), 278-285, 2012
Prions and their partners in crime
B Caughey, GS Baron
Nature 443 (7113), 803-810, 2006
Getting a grip on prions: oligomers, amyloids and pathological membrane interactions
B Caughey, GS Baron, B Chesebro, M Jeffrey
Annual review of biochemistry 78, 177, 2009
Evidence of a molecular barrier limiting susceptibility of humans, cattle and sheep to chronic wasting disease
GJ Raymond, A Bossers, LD Raymond, KI O'rourke, LE McHolland, ...
The EMBO journal 19 (17), 4425-4430, 2000
Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking
R Atarashi, JM Wilham, L Christensen, AG Hughson, RA Moore, ...
Nature methods 5 (3), 211-212, 2008
Sistema negali atlikti operacijos. Bandykite vėliau dar kartą.
Straipsniai 1–20