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Jared Toettcher
Jared Toettcher
Associate Professor, Princeton University
Verified email at princeton.edu - Homepage
Title
Cited by
Cited by
Year
Spatiotemporal control of intracellular phase transitions using light-activated optoDroplets
Y Shin, J Berry, N Pannucci, MP Haataja, JE Toettcher, CP Brangwynne
Cell 168 (1), 159-171. e14, 2017
7652017
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
LS Weinberger, JC Burnett, JE Toettcher, AP Arkin, DV Schaffer
Cell 122 (2), 169-182, 2005
7302005
Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module
JE Toettcher, OD Weiner, WA Lim
Cell 155 (6), 1422-1434, 2013
5752013
Mapping local and global liquid phase behavior in living cells using photo-oligomerizable seeds
D Bracha, MT Walls, MT Wei, L Zhu, M Kurian, JL Avalos, JE Toettcher, ...
Cell 175 (6), 1467-1480. e13, 2018
3462018
Optogenetic regulation of engineered cellular metabolism for microbial chemical production
EM Zhao, Y Zhang, J Mehl, H Park, MA Lalwani, JE Toettcher, JL Avalos
Nature 555 (7698), 683-687, 2018
3462018
Four key steps control glycolytic flux in mammalian cells
LB Tanner, AG Goglia, MH Wei, T Sehgal, LR Parsons, JO Park, E White, ...
Cell systems 7 (1), 49-62. e8, 2018
3312018
Light-based feedback for controlling intracellular signaling dynamics
JE Toettcher, D Gong, WA Lim, OD Weiner
Nature methods 8 (10), 837-839, 2011
3152011
The promise of optogenetics in cell biology: interrogating molecular circuits in space and time
JE Toettcher, CA Voigt, OD Weiner, WA Lim
Nature methods 8 (1), 35-38, 2011
2832011
Light-based control of metabolic flux through assembly of synthetic organelles
EM Zhao, N Suek, MZ Wilson, E Dine, NL Pannucci, Z Gitai, JL Avalos, ...
Nature chemical biology 15 (6), 589-597, 2019
2192019
The spatiotemporal limits of developmental Erk signaling
HE Johnson, Y Goyal, NL Pannucci, T Schüpbach, SY Shvartsman, ...
Developmental cell 40 (2), 185-192, 2017
1912017
Protein phase separation provides long-term memory of transient spatial stimuli
E Dine, AA Gil, G Uribe, CP Brangwynne, JE Toettcher
Cell systems 6 (6), 655-663. e5, 2018
1552018
Tracing information flow from Erk to target gene induction reveals mechanisms of dynamic and combinatorial control
MZ Wilson, PT Ravindran, WA Lim, JE Toettcher
Molecular cell 67 (5), 757-769. e5, 2017
1522017
Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway
LJ Bugaj, AJ Sabnis, A Mitchell, JE Garbarino, JE Toettcher, TG Bivona, ...
Science 361 (6405), eaao3048, 2018
1452018
Viral DNA sensors IFI16 and cyclic GMP-AMP synthase possess distinct functions in regulating viral gene expression, immune defenses, and apoptotic responses during herpesvirus …
BA Diner, KK Lum, JE Toettcher, IM Cristea
MBio 7 (6), 10.1128/mbio. 01553-16, 2016
1452016
Distinct mechanisms act in concert to mediate cell cycle arrest
JE Toettcher, A Loewer, GJ Ostheimer, MB Yaffe, B Tidor, G Lahav
Proceedings of the National Academy of Sciences 106 (3), 785-790, 2009
1312009
Optogenetic control of protein binding using light-switchable nanobodies
AA Gil, C Carrasco-López, L Zhu, EM Zhao, PT Ravindran, MZ Wilson, ...
Nature communications 11 (1), 4044, 2020
1242020
Signaling dynamics control cell fate in the early Drosophila embryo
HE Johnson, JE Toettcher
Developmental cell 48 (3), 361-370. e3, 2019
1192019
Stimulus design for model selection and validation in cell signaling
JF Apgar, JE Toettcher, D Endy, FM White, B Tidor
PLoS computational biology 4 (2), e30, 2008
972008
A bright future: optogenetics to dissect the spatiotemporal control of cell behavior
AG Goglia, JE Toettcher
Current opinion in chemical biology 48, 106-113, 2019
952019
A synthetic–natural hybrid oscillator in human cells
JE Toettcher, C Mock, E Batchelor, A Loewer, G Lahav
Proceedings of the National Academy of Sciences 107 (39), 17047-17052, 2010
882010
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