Synergy between active efflux and outer membrane diffusion defines rules of antibiotic permeation into Gram-negative bacteria G Krishnamoorthy, IV Leus, JW Weeks, D Wolloscheck, VV Rybenkov, ... MBio 8 (5), 10.1128/mbio. 01172-17, 2017 | 166 | 2017 |
Breaking the permeability barrier of Escherichia coli by controlled hyperporination of the outer membrane G Krishnamoorthy, D Wolloscheck, JW Weeks, C Croft, VV Rybenkov, ... Antimicrobial agents and chemotherapy 60 (12), 7372-7381, 2016 | 126 | 2016 |
Substrate specificities and efflux efficiencies of RND efflux pumps of Acinetobacter baumannii IV Leus, JW Weeks, V Bonifay, L Smith, S Richardson, HI Zgurskaya Journal of bacteriology 200 (13), 10.1128/jb. 00049-18, 2018 | 105 | 2018 |
Mechanism of coupling drug transport reactions located in two different membranes HI Zgurskaya, JW Weeks, AT Ntreh, LM Nickels, D Wolloscheck Frontiers in microbiology 6, 100, 2015 | 77 | 2015 |
AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening JW Weeks, T Celaya‐Kolb, S Pecora, R Misra Molecular microbiology 75 (6), 1468-1483, 2010 | 50 | 2010 |
Genetic assessment of the role of AcrB β‐hairpins in the assembly of the TolC–AcrAB multidrug efflux pump of Escherichia coli JW Weeks, VN Bavro, R Misra Molecular Microbiology 91 (5), 965-975, 2014 | 38 | 2014 |
Non‐equivalent roles of two periplasmic subunits in the function and assembly of triclosan pump TriABC from Pseudomonas aeruginosa JW Weeks, LM Nickels, AT Ntreh, HI Zgurskaya Molecular microbiology 98 (2), 343-356, 2015 | 30 | 2015 |
Lack of evidence of nosocomial cross-infection byBurkholderia cepacia among danish cystic fibrosis patients HC Ryley, B Ojeniyi, N Høiby, J Weeks European Journal of Clinical Microbiology and Infectious Diseases 15, 755-758, 1996 | 22 | 1996 |
Characterisation of Burkholderia cepacia from cystic fibrosis patients living in Wales by PCR ribotyping HC Ryley, L Millar-Jones, A Paull, J Weeks Journal of medical microbiology 43 (6), 436-441, 1995 | 22 | 1995 |
Efflux pumps of Burkholderia thailandensis control the permeability barrier of the outer membrane G Krishnamoorthy, JW Weeks, Z Zhang, CE Chandler, H Xue, ... Antimicrobial Agents and Chemotherapy 63 (10), 10.1128/aac. 00956-19, 2019 | 19 | 2019 |
Opening the channel: the two functional interfaces of Pseudomonas aeruginosa OpmH with the triclosan efflux pump TriABC AT Ntreh, JW Weeks, LM Nickels, HI Zgurskaya Journal of bacteriology 198 (23), 3176-3185, 2016 | 19 | 2016 |
Reversal of the drug binding pocket defects of the AcrB multidrug efflux pump protein of Escherichia coli K Soparkar, AD Kinana, JW Weeks, KD Morrison, H Nikaido, R Misra Journal of bacteriology 197 (20), 3255-3264, 2015 | 19 | 2015 |
A “drug sweeping” state of the TriABC triclosan efflux pump from Pseudomonas aeruginosa L Fabre, AT Ntreh, A Yazidi, IV Leus, JW Weeks, S Bhattacharyya, ... Structure 29 (3), 261-274. e6, 2021 | 13 | 2021 |
Property space mapping of Pseudomonas aeruginosa permeability to small molecules IV Leus, JW Weeks, V Bonifay, Y Shen, L Yang, CJ Cooper, D Nath, ... Scientific reports 12 (1), 8220, 2022 | 9 | 2022 |
The research gap in Non-tuberculous Mycobacterium (NTM) and reusable medical devices JW Weeks, K Segars, S Guha Frontiers in Public Health 8, 550260, 2020 | 4 | 2020 |
Multidrug efflux in the context of two-membrane cell envelopes HI Zgurskaya, VN Bavro, JW Weeks, G Krishnamoorthy Efflux-Mediated Antimicrobial Resistance in Bacteria: Mechanisms, Regulation …, 2016 | 2 | 2016 |
Author Correction: Property space mapping of Pseudomonas aeruginosa permeability to small molecules IV Leus, JW Weeks, V Bonifay, Y Shen, L Yang, CJ Cooper, D Nath, ... Scientific reports 13, 2023 | | 2023 |
A Methodology for Investigating Aerosolization of Nontuberculous Mycobacteria From Contaminated Heater Cooler Devices S Guha, D Wolloscheck, N Abdali, C Wentz, N Gillette, KA Bauer, ... Frontiers in Water 4, 902872, 2022 | | 2022 |
Pore-modified gram-negative bacteria and uses thereof H Zgurskaya, JW Weeks US Patent 11,021,521, 2021 | | 2021 |
Substrate Specificities and Efflux Efficiencies of RND Efflux Pumps of Acinetobacter baumannii (vol 200, e00049-18, 2018) IV Leus, JW Weeks, V Bonifay, L Smith, S Richardson, HI Zgurskaya JOURNAL OF BACTERIOLOGY 202 (8), 2020 | | 2020 |