Xiongyi Huang
Xiongyi Huang
Assistant Professor of Chemistry, Johns Hopkins University (as of August 2019)
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Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins
X Huang, JT Groves
Chemical Reviews 118 (5), 2491-2553, 2018
Oxidative aliphatic C–H fluorination with fluoride ion catalyzed by a manganese porphyrin
W Liu, X Huang, MJ Cheng, RJ Nielsen, WA Goddard, JT Groves
Science 337 (6100), 1322-1325, 2012
Manganese-Catalyzed Late-Stage Aliphatic C–H Azidation
X Huang, TM Bergsten, JT Groves
Journal of the American Chemical Society 137 (16), 5300-5303, 2015
Genetically programmed chiral organoborane synthesis
SBJ Kan, X Huang, Y Gumulya, K Chen, FH Arnold
Nature 552, 132–136, 2017
Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C–H activation
X Huang, JT Groves
Journal of Biological Inorganic Chemistry 22 (2-3), 185-207, 2017
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
RK Zhang, K Chen, X Huang, L Wohlschlager, H Renata, FH Arnold
Nature 565, 67–72, 2019
Late Stage Benzylic C–H Fluorination with [18F] Fluoride for PET Imaging
X Huang, W Liu, H Ren, R Neelamegam, JM Hooker, JT Groves
Journal of the American Chemical Society 136 (19), 6842-6845, 2014
Enzymatic construction of highly strained carbocycles
K Chen, X Huang, SBJ Kan, RK Zhang, FH Arnold
Science 360 (6384), 71-75, 2018
Taming Azide Radicals for Catalytic C–H Azidation
X Huang, JT Groves
ACS catalysis 6, 751-759, 2016
Targeted fluorination with the fluoride ion by manganese‐catalyzed decarboxylation
X Huang, W Liu, JM Hooker, JT Groves
Angewandte Chemie International Edition 127 (17), 5330-5334, 2015
Selective C–H bond functionalization with engineered heme proteins: new tools to generate complexity
RK Zhang, X Huang, FH Arnold
Current Opinion in Chemical Biology 49, 67-75, 2019
Enantiodivergent α-Amino C–H Fluoroalkylation Catalyzed by Engineered Cytochrome P450s
J Zhang, X Huang, RK Zhang, FH Arnold
Journal of the American Chemical Society, 2019
A biocatalytic platform for synthesis of chiral α-trifluoromethylated organoborons
X Huang, M Garcia-Borrās, K Miao, SBJ Kan, A Zutshi, KN Houk, ...
ACS Central Science 5 (2), 270-276, 2019
Site-selective (18)F fluorination of unactivated C–H bonds mediated by a manganese porphyrin
W Liu, X Huang, MS Placzek, SW Krska, P McQuade, JM Hooker, ...
Chemical Science 9, 1168-1172, 2018
The Enigmatic P450 Decarboxylase OleT is Capable of, but Evolved to Frustrate, Oxygen Rebound Chemistry
TMM Chun H Hsieh, Xiongyi Huang, Jose A Amaya, Cooper D Rutland, Carson L ...
Biochemistry 56 (26), 3347-3357, 2017
Alkyl Isocyanates via Manganese-Catalyzed C-H Activation for the Preparation of Substituted Ureas
X Huang, T Zhuang, PA Kates, H Gao, X Chen, JT Groves
Journal of the American Chemical Society 139 (43), 15407-15413, 2017
Oxidative aliphatic CH fluorination with manganese catalysts and fluoride ion
W Liu, X Huang, JT Groves
Nature protocols 8 (12), 2348, 2013
Parallel and competitive pathways for substrate desaturation, hydroxylation, and radical rearrangement by the non-heme diiron hydroxylase AlkB
HLR Cooper, G Mishra, X Huang, M Pender-Cudlip, RN Austin, ...
Journal of the American Chemical Society 134 (50), 20365-20375, 2012
A theoretical study on C−COOH homolytic bond dissociation enthalpies
J Shi, XY Huang, JP Wang, R Li
Journal of Physical Chemistry A 114 (21), 6263-6272, 2010
Theoretical study on acidities of (S)-proline amide derivatives in DMSO and its implications for organocatalysis
XY Huang, HJ Wang, J Shi
Journal of Physical Chemistry A 114 (2), 1068-1081, 2009
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