| Identifying inhibitors of inflammation: a novel high-throughput MALDI-TOF screening assay for salt-inducible kinases (SIKs) RE Heap, AG Hope, LA Pearson, KMSE Reyskens, SP McElroy, ... SLAS DISCOVERY: Advancing Life Sciences R&D 22 (10), 1193-1202, 2017 | 56 | 2017 |
| Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation RE Heap, JL Marín-Rubio, J Peltier, T Heunis, A Dannoura, A Moore, ... Life science alliance 4 (6), 2021 | 45 | 2021 |
| Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders M Kurzawa-Akanbi, S Tammireddy, I Fabrik, L Gliaudelytė, MK Doherty, ... Acta neuropathologica 142, 961-984, 2021 | 36 | 2021 |
| Mass spectrometry techniques for studying the ubiquitin system RE Heap, MS Gant, F Lamoliatte, J Peltier, M Trost Biochemical Society Transactions 45 (5), 1137-1148, 2017 | 31 | 2017 |
| A direct-to-biology high-throughput chemistry approach to reactive fragment screening RP Thomas, RE Heap, F Zappacosta, EK Grant, P Pogány, S Besley, ... Chemical science 12 (36), 12098-12106, 2021 | 30 | 2021 |
| Advances in high‐throughput mass spectrometry in drug discovery ME Dueñas, RE Peltier‐Heap, M Leveridge, RS Annan, FH Büttner, ... EMBO Molecular Medicine 15 (1), e14850, 2023 | 22 | 2023 |
| Profiling embryonic stem cell differentiation by MALDI TOF mass spectrometry: development of a reproducible and robust sample preparation workflow RE Heap, A Segarra-Fas, AP Blain, GM Findlay, M Trost Analyst 144 (21), 6371-6381, 2019 | 13 | 2019 |
| Efficient ligand discovery using sulfur (VI) fluoride reactive fragments A Aatkar, A Vuorinen, OE Longfield, K Gilbert, R Peltier-Heap, CD Wagner, ... ACS Chemical Biology 18 (9), 1926-1937, 2023 | 12 | 2023 |
| A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1 L Müller, AK Burton, CL Tayler, JE Rowedder, JP Hutchinson, S Peace, ... SLAS Discovery 28 (1), 3-11, 2023 | 6 | 2023 |
| A chemoproteomic platform for selective deubiquitinase inhibitor discovery R Cookson, A Vuorinen, J Pettinger, CR Kennedy, JM Kirkpatrick, ... Cell Reports Physical Science 4 (10), 2023 | 4 | 2023 |
| A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia JL Marin-Rubio, RE Peltier-Heap, ME Dueñas, T Heunis, A Dannoura, ... Journal of Medicinal Chemistry 65 (18), 12014-12030, 2022 | 4 | 2022 |
| Complement membrane attack complex is an immunometabolic regulator of NLRP3 activation and IL-18 secretion in human macrophages G Jimenez-Duran, J Kozole, R Peltier-Heap, ER Dickinson, ... Frontiers in Immunology 13, 918551, 2022 | 2 | 2022 |
| A MALDI-TOF assay identifies nilotinib as an inhibitor of inflammation in acute myeloid leukaemia JL Marín-Rubio, RE Heap, T Heunis, ME Dueñas, J Inns, J Scott, ... bioRxiv, 2021.03. 29.437557, 2021 | 1 | 2021 |
| A chemoproteomic platform for reactive fragment profiling against the deubiquitinases R Cookson, A Vuorinen, J Pettinger, CR Kennedy, JM Kirkpatrick, ... bioRxiv, 2023.02. 01.526632, 2023 | | 2023 |
| Sublytic membrane attack complex drives glycolysis and mitochondrial dysfunction with inflammatory consequences in human monocyte-derived macrophages G Jimenez-Duran, J Kozole, RE Heap, E Dickinson, C Kwiatkowski, ... | | 2021 |
| Development of mass spectrometric approaches to advance drug discovery RE Heap Newcastle University, 2020 | | 2020 |
| Development of a high-throughput MALDI-TOF MS drug discovery assay for ERAP1 L Müller, S Peace, M Leveridge, M Trost, R Peltier-Heap, ME Dueñas | | |
