Kambez H. Benam, D.Phil.
Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro
KH Benam, R Villenave, C Lucchesi, A Varone, C Hubeau, HH Lee, ...
Nature methods 13 (2), 151-157, 2016
Engineered in vitro disease models
KH Benam, S Dauth, B Hassell, A Herland, A Jain, KJ Jang, K Karalis, ...
Annual Review of Pathology: Mechanisms of Disease 10, 195-262, 2015
Matched-comparative modeling of normal and diseased human airway responses using a microengineered breathing lung chip
KH Benam, R Novak, J Nawroth, M Hirano-Kobayashi, TC Ferrante, ...
Cell systems 3 (5), 456-466. e4, 2016
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics
L Si, H Bai, M Rodas, W Cao, CY Oh, A Jiang, R Moller, D Hoagland, ...
Nature biomedical engineering 5 (8), 815-829, 2021
Pivotal advance: invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during severe influenza A virus infection
WL Kok, L Denney, K Benam, S Cole, C Clelland, AJ McMichael, LP Ho
Journal of leukocyte biology 91 (3), 357-368, 2012
M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza
SL Cole, J Dunning, WL Kok, KH Benam, A Benlahrech, E Repapi, ...
JCI insight 2 (7), 2017
Human organs-on-chips as tools for repurposing approved drugs as potential influenza and COVID19 therapeutics in viral pandemics
L Si, H Bai, M Rodas, W Cao, CY Oh, A Jiang, A Nurani, DY Zhu, G Goyal, ...
BioRxiv 13, 2020, 2020
Low shear microfluidic devices and methods of use and manufacturing thereof
DE Ingber, KH Benam, R Villenave, GA Hamilton, B Hassell, CD Hinojosa
US Patent WO2015138034 A2, 2015
Human lung small airway-on-a-chip protocol
KH Benam, M Mazur, Y Choe, TC Ferrante, R Novak, DE Ingber
3D Cell Culture: Methods and Protocols, 345-365, 2017
Organomimetic devices and methods of use and manufacturing thereof
J Fernandez-Alcon, N Wen, R Novak, DE Ingber, GA Hamilton, ...
US Patent WO2015138032 A2, 2015
Biomimetic smoking robot for in vitro inhalation exposure compatible with microfluidic organ chips
KH Benam, R Novak, TC Ferrante, Y Choe, DE Ingber
Nature protocols 15 (2), 183-206, 2020
Exploring new technologies in biomedical research
KH Benam, S Gilchrist, A Kleensang, AB Satz, C Willett, Q Zhang
Drug discovery today 24 (6), 1242-1247, 2019
How the respiratory epithelium senses and reacts to influenza virus
KH Benam, L Denney, LP Ho
American Journal of Respiratory Cell and Molecular Biology 60 (3), 259-268, 2019
Advanced microengineered lung models for translational drug discovery
BF Niemeyer, P Zhao, RM Tuder, KH Benam
SLAS DISCOVERY: Advancing Life Sciences R&D 23 (8), 777-789, 2018
Human organ chip-enabled pipeline to rapidly repurpose therapeutics during viral pandemics
L Si, H Bai, M Rodas, W Cao, CY Oh, A Jiang, R Moller, D Hoagland, ...
BioRxiv, 2020.04. 13.039917, 2020
Mucociliary defense: emerging cellular, molecular, and animal models
KH Benam, EK Vladar, WJ Janssen, CM Evans
Annals of the American Thoracic Society 15 (Supplement 3), S210-S215, 2018
Where we stand: lung organotypic living systems that emulate human-relevant host–environment/pathogen interactions
RJ Jimenez-Valdes, UI Can, BF Niemeyer, KH Benam
Frontiers in Bioengineering and Biotechnology 8, 989, 2020
Discovery of influenza drug resistance mutations and host therapeutic targets using a human airway chip
L Si, R Prantil-Baun, KH Benam, H Bai, M Rodas, M Burt, DE Ingber
BioRxiv, 685552, 2019
Breaking the In Vitro Barrier in Respiratory Medicine. Engineered Microphysiological Systems for Chronic Obstructive Pulmonary Disease and Beyond
KH Benam, M Königshoff, O Eickelberg
American Journal of Respiratory and Critical Care Medicine 197 (7), 869-875, 2018
Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip. Cell Syst 3: 456–466. e4
KH Benam, R Novak, J Nawroth, M Hirano-Kobayashi, TC Ferrante, ...
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Straipsniai 1–20