| Discovery of GDC-0853: a potent, selective, and noncovalent Bruton’s tyrosine kinase inhibitor in early clinical development JJ Crawford, AR Johnson, DL Misner, LD Belmont, G Castanedo, R Choy, ... Journal of medicinal chemistry 61 (6), 2227-2245, 2018 | 218 | 2018 |
| Mechanochromism of piroxicam accompanied by intermolecular proton transfer probed by spectroscopic methods and solid-phase changes AR Sheth, JW Lubach, EJ Munson, FX Muller, DJW Grant Journal of the American Chemical Society 127 (18), 6641-6651, 2005 | 173 | 2005 |
| Investigation of drug–excipient interactions in lapatinib amorphous solid dispersions using solid-state NMR spectroscopy Y Song, X Yang, X Chen, H Nie, S Byrn, JW Lubach Molecular pharmaceutics 12 (3), 857-866, 2015 | 144 | 2015 |
| Investigation of the effects of pharmaceutical processing upon solid-state NMR relaxation times and implications to solid-state formulation stability JW Lubach, D Xu, BE Segmuller, EJ Munson Journal of pharmaceutical sciences 96 (4), 777-787, 2007 | 114 | 2007 |
| Significant species difference in amide hydrolysis of GDC-0834, a novel potent and selective Bruton's tyrosine kinase inhibitor L Liu, JS Halladay, Y Shin, S Wong, M Coraggio, H La, M Baumgardner, ... Drug metabolism and disposition 39 (10), 1840-1849, 2011 | 77 | 2011 |
| Acid–base interactions of polystyrene sulfonic acid in amorphous solid dispersions using a combined UV/FTIR/XPS/ssNMR study Y Song, D Zemlyanov, X Chen, H Nie, Z Su, K Fang, X Yang, D Smith, ... Molecular pharmaceutics 13 (2), 483-492, 2016 | 70 | 2016 |
| Characterization of pharmaceutical cocrystals and salts by dynamic nuclear polarization-enhanced solid-state NMR spectroscopy L Zhao, MP Hanrahan, P Chakravarty, AG DiPasquale, LE Sirois, ... Crystal Growth & Design 18 (4), 2588-2601, 2018 | 69 | 2018 |
| Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell–associated damage in IFNα-driven lupus nephritis A Katewa, Y Wang, JA Hackney, T Huang, E Suto, N Ramamoorthi, ... JCI insight 2 (7), 2017 | 63 | 2017 |
| Potent and selective Bruton’s tyrosine kinase inhibitors: Discovery of GDC-0834 WB Young, J Barbosa, P Blomgren, MC Bremer, JJ Crawford, D Dambach, ... Bioorganic & Medicinal Chemistry Letters 25 (6), 1333-1337, 2015 | 61 | 2015 |
| The role of lymphatic transport on the systemic bioavailability of the Bcl-2 protein family inhibitors navitoclax (ABT-263) and ABT-199 EF Choo, J Boggs, C Zhu, JW Lubach, ND Catron, G Jenkins, AJ Souers, ... Drug Metabolism and Disposition 42 (2), 207-212, 2014 | 55 | 2014 |
| Impact of method of preparation of amorphous solid dispersions on mechanical properties: comparison of coprecipitation and spray drying HH Hou, A Rajesh, KM Pandya, JW Lubach, A Muliadi, E Yost, W Jia, ... Journal of pharmaceutical sciences 108 (2), 870-879, 2019 | 53 | 2019 |
| Solid-state NMR studies of pharmaceutical solids in polymer matrices JW Lubach, BE Padden, SL Winslow, JS Salsbury, DB Masters, EM Topp, ... Analytical and bioanalytical chemistry 378, 1504-1510, 2004 | 49 | 2004 |
| Acid-base interactions in amorphous solid dispersions of lumefantrine prepared by spray-drying and hot-melt extrusion using X-ray photoelectron spectroscopy Y Song, D Zemlyanov, X Chen, Z Su, H Nie, JW Lubach, D Smith, S Byrn, ... International journal of pharmaceutics 514 (2), 456-464, 2016 | 43 | 2016 |
| Fast acquisition of proton‐detected HETCOR solid‐state NMR spectra of quadrupolar nuclei and rapid measurement of NH bond lengths by frequency selective HMQC and RESPDOR pulse … AV Wijesekara, A Venkatesh, BJ Lampkin, B VanVeller, JW Lubach, ... Chemistry–A European Journal 26 (35), 7881-7888, 2020 | 40 | 2020 |
| Discovery of highly potent and selective Bruton’s tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability WB Young, J Barbosa, P Blomgren, MC Bremer, JJ Crawford, D Dambach, ... Bioorganic & Medicinal Chemistry Letters 26 (2), 575-579, 2016 | 39 | 2016 |
| Rapid Characterization of Formulated Pharmaceuticals Using Fast MAS 1H Solid-State NMR Spectroscopy DA Hirsh, AV Wijesekara, SL Carnahan, I Hung, JW Lubach, K Nagapudi, ... Molecular Pharmaceutics 16 (7), 3121-3132, 2019 | 38 | 2019 |
| A rational approach towards development of amorphous solid dispersions: experimental and computational techniques P Chakravarty, JW Lubach, J Hau, K Nagapudi International Journal of Pharmaceutics 519 (1-2), 44-57, 2017 | 38 | 2017 |
| Multiple-sample probe for solid-state NMR studies of pharmaceuticals BN Nelson, LJ Schieber, DH Barich, JW Lubach, TJ Offerdahl, DH Lewis, ... Solid state nuclear magnetic resonance 29 (1-3), 204-213, 2006 | 38 | 2006 |
| Investigation of the rat model for preclinical evaluation of pH-dependent oral absorption in humans JW Lubach, JZ Chen, J Hau, J Imperio, M Coraggio, L Liu, H Wong Molecular pharmaceutics 10 (11), 3997-4004, 2013 | 37 | 2013 |
| Enhancing the resolution of 1 H and 13 C solid-state NMR spectra by reduction of anisotropic bulk magnetic susceptibility broadening MP Hanrahan, A Venkatesh, SL Carnahan, JL Calahan, JW Lubach, ... Physical Chemistry Chemical Physics 19 (41), 28153-28162, 2017 | 36 | 2017 |
