Macrocyclic drugs and synthetic methodologies toward macrocycles X Yu, D Sun Molecules 18 (6), 6230-6268, 2013 | 271 | 2013 |
Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux RE Lee, JG Hurdle, J Liu, DF Bruhn, T Matt, MS Scherman, PK Vaddady, ... Nature medicine 20 (2), 152-158, 2014 | 191 | 2014 |
Recent synthetic developments and applications of the ullmann reaction. A review H Lin, D Sun Organic preparations and procedures international 45 (5), 341-394, 2013 | 154 | 2013 |
The structure–activity relationship of urea derivatives as anti-tuberculosis agents JR Brown, EJ North, JG Hurdle, C Morisseau, JS Scarborough, D Sun, ... Bioorganic & medicinal chemistry 19 (18), 5585-5595, 2011 | 139 | 2011 |
Discovery of novel isoxazolines as anti-tuberculosis agents RP Tangallapally, D Sun, N Budha, REB Lee, AJM Lenaerts, B Meibohm, ... Bioorganic & medicinal chemistry letters 17 (23), 6638-6642, 2007 | 124 | 2007 |
Synthesis, structure–activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives L Feng, MM Maddox, MZ Alam, LS Tsutsumi, G Narula, DF Bruhn, X Wu, ... Journal of medicinal chemistry 57 (20), 8398-8420, 2014 | 115 | 2014 |
Carbazole scaffold in medicinal chemistry and natural products: a review from 2010-2015 L S Tsutsumi, D Gündisch, D Sun Current Topics in Medicinal Chemistry 16 (11), 1290-1313, 2016 | 104 | 2016 |
Identification of triazinoindol-benzimidazolones as nanomolar inhibitors of the Mycobacterium tuberculosis enzyme TDP-6-deoxy-d-xylo-4-hexopyranosid-4-ulose 3, 5-epimerase (RmlC) S Sivendran, V Jones, D Sun, Y Wang, AE Grzegorzewicz, MS Scherman, ... Bioorganic & medicinal chemistry 18 (2), 896-908, 2010 | 96 | 2010 |
Synthesis, optimization and structure–activity relationships of 3, 5-disubstituted isoxazolines as new anti-tuberculosis agents D Sun, RB Lee, RP Tangallapally, RE Lee European journal of medicinal chemistry 44 (2), 460-472, 2009 | 96 | 2009 |
Progress in the discovery of treatments for C. difficile infection: a clinical and medicinal chemistry review L S Tsutsumi, Y B Owusu, J G Hurdle, D Sun Current topics in medicinal chemistry 14 (1), 152-175, 2014 | 55 | 2014 |
Recent advances of natural and synthetic β-carbolines as anticancer agents M Zhang, D Sun Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2015 | 53 | 2015 |
Evaluation of flavonoid and resveratrol chemical libraries reveals abyssinone II as a promising antibacterial lead D Sun, JG Hurdle, RE Lee, RE Lee, M Cushman, JM Pezzuto ChemMedChem 7 (9), 1541, 2012 | 48 | 2012 |
Total synthesis and structural revision of engelhardione L Shen, D Sun Tetrahedron letters 52 (35), 4570-4574, 2011 | 38 | 2011 |
Solid-phase synthesis and biological evaluation of a uridinyl branched peptide urea library D Sun, V Jones, EI Carson, REB Lee, MS Scherman, MR McNeil, RE Lee Bioorganic & medicinal chemistry letters 17 (24), 6899-6904, 2007 | 36 | 2007 |
The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection RKR Marreddy, X Wu, M Sapkota, AM Prior, JA Jones, D Sun, ... ACS infectious diseases 5 (2), 208-217, 2018 | 35 | 2018 |
Evaluation of analogs of reutericyclin as prospective candidates for treatment of staphylococcal skin infections JG Hurdle, R Yendapally, D Sun, RE Lee Antimicrobial agents and chemotherapy 53 (9), 4028-4031, 2009 | 35 | 2009 |
Macrocycle-antibiotic hybrids: A path to clinical candidates AS Surur, D Sun Frontiers in Chemistry 9, 659845, 2021 | 34 | 2021 |
Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors X Yu, EJ Park, TP Kondratyuk, JM Pezzuto, D Sun Organic & biomolecular chemistry 10 (44), 8835-8847, 2012 | 31 | 2012 |
Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1 AM Prior, X Yu, EJ Park, TP Kondratyuk, Y Lin, JM Pezzuto, D Sun Bioorganic & medicinal chemistry letters 27 (24), 5393-5399, 2017 | 29 | 2017 |
Synthesis and antibacterial evaluation of anziaic acid and its analogues as topoisomerase I inhibitors H Lin, T Annamalai, P Bansod, YC Tse-Dinh, D Sun MedChemComm 4 (12), 1613-1618, 2013 | 29 | 2013 |