Christoph Helma
Christoph Helma
in silico toxicology gmbh
Patvirtintas el. paštas
Data mining and machine learning techniques for the identification of mutagenicity inducing substructures and structure activity relationships of noncongeneric compounds
C Helma, T Cramer, S Kramer, L De Raedt
Journal of chemical information and computer sciences 44 (4), 1402-1411, 2004
Molecular feature mining in HIV data
S Kramer, L De Raedt, C Helma
Proceedings of the seventh ACM SIGKDD international conference on Knowledge …, 2001
The predictive toxicology challenge 2000–2001
C Helma, RD King, S Kramer, A Srinivasan
Bioinformatics 17 (1), 107-108, 2001
Genotoxic effects of heavy metals: comparative investigation with plant bioassays
H Steinkellner, K Mun‐Sik, C Helma, S Ecker, TH Ma, O Horak, M Kundi, ...
Environmental and molecular mutagenesis 31 (2), 183-191, 1998
A public domain image-analysis program for the single-cell gel-electrophoresis (comet) assay
C Helma, M Uhl
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466 (1), 9-15, 2000
Statistical evaluation of the predictive toxicology challenge 2000–2001
H Toivonen, A Srinivasan, RD King, S Kramer, C Helma
Bioinformatics 19 (10), 1183-1193, 2003
Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells
M Uhl, C Helma, S Knasmüller
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 468 (2 …, 2000
lazar: a modular predictive toxicology framework
A Maunz, M Gütlein, M Rautenberg, D Vorgrimmler, D Gebele, C Helma
Frontiers in Pharmacology 4 (38), 2013
Data quality in predictive toxicology: reproducibility of rodent carcinogenicity experiments.
E Gottmann, S Kramer, B Pfahringer, C Helma
Environmental health perspectives 109 (5), 509-514, 2001
Single-cell gel electrophoresis assays with human-derived hepatoma (Hep G2) cells
M Uhl, C Helma, S Knasmüller
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 441 (2 …, 1999
Collaborative development of predictive toxicology applications
B Hardy, N Douglas, C Helma, M Rautenberg, N Jeliazkova, V Jeliazkov, ...
Journal of cheminformatics 2 (1), 1-29, 2010
Lazy structure-activity relationships (lazar) for the prediction of rodent carcinogenicity and Salmonella mutagenicity
C Helma
Molecular diversity 10 (2), 147-158, 2006
The expanding role of predictive toxicology: an update on the (Q) SAR models for mutagens and carcinogens
R Benigni, TI Netzeva, E Benfenati, C Bossa, R Franke, C Helma, ...
Journal of Environmental Science and Health Part C 25 (1), 53-97, 2007
Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo [4, 5-f] quinoline (IQ)-induced genotoxic effects and colonic …
F Kassie, S Rabot, M Uhl, W Huber, HM Qin, C Helma, ...
Carcinogenesis 23 (7), 1155-1161, 2002
Predictive models for carcinogenicity and mutagenicity: frameworks, state-of-the-art, and perspectives
E Benfenati, R Benigni, DM Demarini, C Helma, D Kirkland, TM Martin, ...
Journal of Environmental Science and Health Part C 27 (2), 57-90, 2009
Prediction of adverse drug reactions using decision tree modeling
F Hammann, H Gutmann, N Vogt, C Helma, J Drewe
Clinical Pharmacology & Therapeutics 88 (1), 52-59, 2010
Toxic effects of griseofulvin: disease models, mechanisms, and risk assessment
S Knasmüller, W Parzefall, C Helma, F Kassie, S Ecker, ...
Critical reviews in toxicology 27 (5), 495-537, 1997
Comparative evaluation of four bacterial assays for the detection of genotoxic effects in the dissolved water phases of aqueous matrices
C Helma, V Mersch-Sundermann, VS Houk, U Glasbrenner, C Klein, ...
Environmental science & technology 30 (3), 897-907, 1996
Knowledge discovery and data mining in toxicology
C Helma, E Gottmann, S Kramer
Statistical methods in medical research 9 (4), 329-358, 2000
Stochastic propositionalization of non-determinate background knowledge
S Kramer, B Pfahringer, C Helma
International Conference on Inductive Logic Programming, 80-94, 1998
Sistema negali atlikti operacijos. Bandykite vėliau dar kartą.
Straipsniai 1–20