Methods and protocols of modern solid phase peptide synthesis M Amblard, JA Fehrentz, J Martinez, G Subra Molecular biotechnology 33, 239-254, 2006 | 745 | 2006 |
An efficient synthesis of optically active α-(t-butoxycarbonylamino)-aldehydes from α-amino acids JA Fehrentz, B Castro Synthesis 1983 (08), 676-678, 1983 | 361 | 1983 |
Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons M Schaeffer, F Langlet, C Lafont, F Molino, DJ Hodson, T Roux, ... Proceedings of the National Academy of Sciences 110 (4), 1512-1517, 2013 | 303 | 2013 |
Synthesis of 3, 4, 5-Trisubstituted-1, 2, 4-triazoles A Moulin, M Bibian, AL Blayo, S El Habnouni, J Martinez, JA Fehrentz Chemical reviews 110 (4), 1809-1827, 2010 | 201 | 2010 |
High constitutive activity is an intrinsic feature of ghrelin receptor protein M Damian, J Marie, JP Leyris, JA Fehrentz, P Verdie, J Martinez, ... Journal of biological chemistry 287 (6), 3630-3641, 2012 | 164 | 2012 |
Palatability can drive feeding independent of AgRP neurons RGP Denis, A Joly-Amado, E Webber, F Langlet, M Schaeffer, SL Padilla, ... Cell metabolism 22 (4), 646-657, 2015 | 151 | 2015 |
Toward potent ghrelin receptor ligands based on trisubstituted 1, 2, 4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations A Moulin, L Demange, G Bergé, D Gagne, J Ryan, D Mousseaux, A Heitz, ... Journal of medicinal chemistry 50 (23), 5790-5806, 2007 | 145 | 2007 |
Solid phase synthesis of chiral 3-substituted quinazoline-2, 4-diones L Gouilleux, JA Fehrentz, F Winternitz, J Martinez Tetrahedron letters 37 (39), 7031-7034, 1996 | 127 | 1996 |
N-terminal liver-expressed antimicrobial peptide 2 (LEAP2) region exhibits inverse agonist activity toward the ghrelin receptor C M’Kadmi, A Cabral, F Barrile, J Giribaldi, S Cantel, M Damian, S Mary, ... Journal of Medicinal Chemistry 62 (2), 965-973, 2018 | 120 | 2018 |
Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor S Mary, M Damian, M Louet, N Floquet, JA Fehrentz, J Marie, J Martinez, ... Proceedings of the National Academy of Sciences 109 (21), 8304-8309, 2012 | 118 | 2012 |
Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. 1 L Demange, D Boeglin, A Moulin, D Mousseaux, J Ryan, G Bergé, ... Journal of medicinal chemistry 50 (8), 1939-1957, 2007 | 118 | 2007 |
Improved solid phase synthesis of C-terminal peptide aldehydes JA Fehrentz, M Paris, A Heitz, J Velek, CF Liu, F Winternitz, J Martinez Tetrahedron letters 36 (43), 7871-7874, 1995 | 112 | 1995 |
Detergent-free isolation of functional G protein-coupled receptors into nanometric lipid particles C Logez, M Damian, C Legros, C Dupré, M Guéry, S Mary, R Wagner, ... Biochemistry 55 (1), 38-48, 2016 | 110 | 2016 |
New active series of growth hormone secretagogues V Guerlavais, D Boeglin, D Mousseaux, C Oiry, A Heitz, R Deghenghi, ... Journal of medicinal chemistry 46 (7), 1191-1203, 2003 | 97 | 2003 |
Agonism, antagonism, and inverse agonism bias at the ghrelin receptor signaling C M'Kadmi, JP Leyris, L Onfroy, C Galés, A Saulière, D Gagne, M Damian, ... Journal of Biological Chemistry 290 (45), 27021-27039, 2015 | 92 | 2015 |
Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a JP Leyris, T Roux, E Trinquet, P Verdié, JA Fehrentz, N Oueslati, ... Analytical biochemistry 408 (2), 253-262, 2011 | 91 | 2011 |
Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor: Gq complex M Damian, S Mary, M Maingot, C M'Kadmi, D Gagne, JP Leyris, ... Proceedings of the National Academy of Sciences 112 (5), 1601-1606, 2015 | 89 | 2015 |
Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus G Osterstock, P Escobar, V Mitutsova, LA Gouty-Colomer, P Fontanaud, ... PLoS One 5 (2), e9159, 2010 | 89 | 2010 |
Regulation of ERK1/2 activity by ghrelin‐activated growth hormone secretagogue receptor 1A involves a PLC/PKCɛ pathway D Mousseaux, L Le Gallic, J Ryan, C Oiry, D Gagne, JA Fehrentz, ... British journal of pharmacology 148 (3), 350-365, 2006 | 89 | 2006 |
Solution and solid-supported synthesis of 3, 4, 5-trisubstituted 1, 2, 4-triazole-based peptidomimetics D Boeglin, S Cantel, A Heitz, J Martinez, JA Fehrentz Organic letters 5 (23), 4465-4468, 2003 | 87 | 2003 |