| PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity F Levitin, M Weiss, Y Hahn, O Stern, RL Papke, R Matusik, SR Nandana, ... Journal of Biological Chemistry 283 (24), 16928-16939, 2008 | 65 | 2008 |
| Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles R Elias, RI Benhamou, QZ Jaber, O Dorot, SL Zada, K Oved, E Pichinuk, ... European journal of medicinal chemistry 179, 779-790, 2019 | 57 | 2019 |
| Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer’s disease-like symptoms in animal model GK Viswanathan, D Shwartz, Y Losev, E Arad, C Shemesh, E Pichinuk, ... Cellular and Molecular Life Sciences 77, 2795-2813, 2020 | 55 | 2020 |
| Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation D Laor, D Sade, S Shaham-Niv, D Zaguri, M Gartner, V Basavalingappa, ... Nature communications 10 (1), 62, 2019 | 54 | 2019 |
| Antibody targeting of cell-bound MUC1 SEA domain kills tumor cells E Pichinuk, I Benhar, O Jacobi, M Chalik, L Weiss, R Ziv, C Sympson, ... Cancer research 72 (13), 3324-3336, 2012 | 44 | 2012 |
| Integrating in vitro and in silico approaches to evaluate the “dual functionality” of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils E Haj, Y Losev, VG KrishnaKumar, E Pichinuk, H Engel, A Raveh, E Gazit, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (7), 1565-1575, 2018 | 33 | 2018 |
| Persistent inflammatory stimulation drives the conversion of MSCs to inflammatory CAFs that promote pro-metastatic characteristics in breast cancer cells L Rubinstein-Achiasaf, D Morein, H Ben-Yaakov, Y Liubomirski, T Meshel, ... Cancers 13 (6), 1472, 2021 | 27 | 2021 |
| Treatment of hereditary hypotrichosis simplex of the scalp with topical gentamicin A Peled, L Samuelov, O Sarig, R Bochner, L Malki, M Pavlovsky, ... British Journal of Dermatology 183 (1), 114-120, 2020 | 25 | 2020 |
| The MUC1 oncoprotein as a functional target: immunotoxin binding to α/β junction mediates cell killing DB Rubinstein, M Karmely, E Pichinuk, R Ziv, I Benhar, N Feng, ... International journal of cancer 124 (1), 46-54, 2009 | 23 | 2009 |
| In vivo anti-MUC1+ tumor activity and sequences of high-affinity anti-MUC1-SEA antibodies E Pichinuk, M Chalik, I Benhar, R Ginat-Koton, R Ziv, NI Smorodinsky, ... Cancer Immunology, Immunotherapy 69, 1337-1352, 2020 | 17 | 2020 |
| Minerval (2-hydroxyoleic acid) causes cancer cell selective toxicity by uncoupling oxidative phosphorylation and compromising bioenergetic compensation capacity W Massalha, M Markovits, E Pichinuk, Y Feinstein-Rotkopf, M Tarshish, ... Bioscience Reports 39 (1), BSR20181661, 2019 | 15 | 2019 |
| MUC1-ARF—a novel MUC1 protein that resides in the nucleus and is expressed by alternate reading frame translation of MUC1 mRNA M Chalick, O Jacobi, E Pichinuk, C Garbar, A Bensussan, A Meeker, R Ziv, ... PLoS One 11 (10), e0165031, 2016 | 13 | 2016 |
| Anti-TNFα treatment impairs long-term immune responses to COVID-19 mRNA vaccine in patients with inflammatory bowel diseases KM Rabinowitz, M Navon, H Edelman-Klapper, E Zittan, A Bar-Gil Shitrit, ... Vaccines 10 (8), 1186, 2022 | 11 | 2022 |
| A differential autophagy-dependent response to DNA double-strand breaks in bone marrow mesenchymal stem cells from sporadic ALS patients S Wald-Altman, E Pichinuk, O Kakhlon, M Weil Disease models & mechanisms 10 (5), 645-654, 2017 | 11 | 2017 |
| Continuous inflammatory stimulation leads via metabolic plasticity to a prometastatic phenotype in triple-negative breast cancer cells D Morein, L Rubinstein-Achiasaf, H Brayer, O Dorot, E Pichinuk, ... Cells 10 (6), 1356, 2021 | 10 | 2021 |
| The antipsychotropic drug Duloxetine rescues PAX6 haploinsufficiency of mutant limbal stem cells through inhibition of the MEK/ERK signaling pathway O Dorot, LN Roux, L Zennaro, K Oved, D Bremond-Gignac, E Pichinuk, ... The Ocular Surface 23, 140-142, 2022 | 7 | 2022 |
| Endogenous RNA cleavages at the ribosomal SRL site likely reflect miRNA (miR) mediated translational suppression E Pichinuk, L Broday, DH Wreschner Biochemical and biophysical research communications 414 (4), 706-711, 2011 | 7 | 2011 |
| Ritanserin, a potent serotonin 2A receptor antagonist, represses MEK/ERK signalling pathway to restore PAX6 production and function in aniridia-like cellular model K Oved, L Zennaro, O Dorot, J Zerbib, E Frank, LN Roux, ... Biochemical and biophysical research communications 582, 100-104, 2021 | 6 | 2021 |
| Targeting cell-bound MUC1 on myelomonocytic, monocytic leukemias and phenotypically defined leukemic stem cells with anti-SEA module antibodies T Guillaume, V Dehame, P Chevallier, P Peterlin, A Garnier, M Grégoire, ... Experimental Hematology 70, 97-108, 2019 | 4 | 2019 |
| Kynurenic acid, a key L-tryptophan-derived metabolite, protects the heart from an ischemic damage E Bigelman, M Pasmanik-Chor, B Dassa, M Itkin, S Malitsky, O Dorot, ... Plos one 18 (8), e0275550, 2023 | 3 | 2023 |
