| Exosome-mediated delivery of hydrophobically modified siRNA for huntingtin mRNA silencing MC Didiot, LM Hall, AH Coles, RA Haraszti, BMDC Godinho, K Chase, ... Molecular Therapy 24 (10), 1836-1847, 2016 | 450 | 2016 |
| Impact of ipsilateral blood draws, injections, blood pressure measurements, and air travel on the risk of lymphedema for patients treated for breast cancer CM Ferguson, MN Swaroop, N Horick, MN Skolny, CL Miller, ... Journal of Clinical Oncology 34 (7), 691, 2016 | 189 | 2016 |
| A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system JF Alterman, BMDC Godinho, MR Hassler, CM Ferguson, D Echeverria, ... Nature biotechnology 37 (8), 884-894, 2019 | 154 | 2019 |
| Impact of adjuvant taxane-based chemotherapy on development of breast cancer-related lymphedema: results from a large prospective cohort MN Swaroop, CM Ferguson, NK Horick, MN Skolny, CL Miller, ... Breast cancer research and treatment 151, 393-403, 2015 | 112 | 2015 |
| Establishing and sustaining a prospective screening program for breast cancer-related lymphedema at the massachusetts general hospital: lessons learned C Brunelle, M Skolny, C Ferguson, M Swaroop, J O’Toole, AG Taghian Journal of personalized medicine 5 (2), 153-164, 2015 | 60 | 2015 |
| Tbx6, Mesp-b and Ripply1 regulate the onset of skeletal myogenesis in zebrafish SE Windner, RA Doris, CM Ferguson, AC Nelson, G Valentin, H Tan, ... Development 142 (6), 1159-1168, 2015 | 59 | 2015 |
| The impact of breast cancer-related lymphedema on the ability to perform upper extremity activities of daily living JA O’Toole, CM Ferguson, MN Swaroop, N Horick, MN Skolny, ... Breast cancer research and treatment 150, 381-388, 2015 | 58 | 2015 |
| Immediate implant reconstruction is associated with a reduced risk of lymphedema compared to mastectomy alone: a prospective cohort study CL Miller, AS Colwell, N Horick, MN Skolny, LS Jammallo, JA O’Toole, ... Annals of surgery 263 (2), 399-405, 2016 | 52 | 2016 |
| Nuclear localization of huntingtin mRNA is specific to cells of neuronal origin MC Didiot, CM Ferguson, S Ly, AH Coles, AO Smith, AA Bicknell, LM Hall, ... Cell reports 24 (10), 2553-2560. e5, 2018 | 46 | 2018 |
| Cell type impacts accessibility of mRNA to silencing by RNA interference CM Ferguson, D Echeverria, M Hassler, S Ly, A Khvorova Molecular Therapy-Nucleic Acids 21, 384-393, 2020 | 28 | 2020 |
| A novel parent questionnaire for the detection of seizures in children LM Douglass, K Kuban, D Tarquinio, L Schraga, R Jonas, T Heeren, ... Pediatric neurology 54, 64-69. e1, 2016 | 20 | 2016 |
| Delivering siRNA compounds during HOPE to modulate organ function: a proof-of-concept study in a rat liver transplant model E Bonaccorsi-Riani, AR Gillooly, S Iesari, IMA Brüggenwirth, ... Transplantation 106 (8), 1565-1576, 2022 | 16 | 2022 |
| Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington’s disease D O'Reilly, J Belgrad, C Ferguson, A Summers, E Sapp, C McHugh, ... Molecular Therapy 31 (6), 1661-1674, 2023 | 14 | 2023 |
| Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection VN Hariharan, M Shin, CW Chang, D O’Reilly, A Biscans, K Yamada, ... Proceedings of the National Academy of Sciences 120 (11), e2219523120, 2023 | 14 | 2023 |
| PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs BMDC Godinho, EG Knox, S Hildebrand, JW Gilbert, D Echeverria, ... Molecular Therapy-Nucleic Acids 29, 116-132, 2022 | 14 | 2022 |
| Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep CM Ferguson, BMDC Godinho, JF Alterman, AH Coles, M Hassler, ... JCI insight 6 (24), 2021 | 11 | 2021 |
| From Failure to Meet the Clinical Endpoint to US Food and Drug Administration Approval: 15th Antisense oligonucleotide therapy approved qalsody (Tofersen) for treatment of SOD1 … W van Roon-Mom, C Ferguson, A Aartsma-Rus nucleic acid therapeutics 33 (4), 234-237, 2023 | 9 | 2023 |
| Mutant huntingtin messenger RNA forms neuronal nuclear clusters in rodent and human brains S Ly, MC Didiot, CM Ferguson, AH Coles, R Miller, K Chase, D Echeverria, ... Brain Communications 4 (6), fcac248, 2022 | 9 | 2022 |
| Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo. K Yamada, VN Hariharan, J Caiazzi, R Miller, C Furguson, E Sapp, ... bioRxiv, 2023 | 5 | 2023 |
| Silencing Apoe with divalent‐siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease CM Ferguson, S Hildebrand, BMDC Godinho, J Buchwald, D Echeverria, ... Alzheimer's & Dementia, 2024 | 3 | 2024 |
