Stebėti
Harshwardhan Poddar
Harshwardhan Poddar
Patvirtintas el. paštas manchester.ac.uk
Pavadinimas
Cituota
Cituota
Metai
Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases
JY van der Meer, H Poddar, BJ Baas, Y Miao, M Rahimi, A Kunzendorf, ...
Nature communications 7 (1), 10911, 2016
912016
Evidence for the formation of an enamine species during aldol and Michael‐type addition reactions promiscuously catalyzed by 4‐oxalocrotonate tautomerase
H Poddar, M Rahimi, EM Geertsema, AMWH Thunnissen, GJ Poelarends
ChemBioChem 16 (5), 738-741, 2015
372015
A guide to time‐resolved structural analysis of light‐activated proteins
H Poddar, DJ Heyes, G Schirò, M Weik, D Leys, NS Scrutton
The FEBS Journal 289 (3), 576-595, 2022
322022
Structural Basis for the Catalytic Mechanism of Ethylenediamine-N,N′-disuccinic Acid Lyase, a Carbon–Nitrogen Bond-Forming Enzyme with a Broad Substrate …
H Poddar, J De Villiers, J Zhang, V Puthan Veetil, H Raj, ...
Biochemistry 57 (26), 3752-3763, 2018
282018
Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs
LN Jeffreys, H Poddar, M Golovanova, CW Levy, HM Girvan, KJ McLean, ...
Scientific Reports 9 (1), 1577, 2019
212019
Structure–Activity Relationships of cyclo(l-Tyrosyl-l-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to …
S Rajput, KJ McLean, H Poddar, IR Selvam, G Nagalingam, JA Triccas, ...
Journal of Medicinal Chemistry 62 (21), 9792-9805, 2019
202019
Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus
HM Girvan, H Poddar, KJ McLean, DR Nelson, KA Hollywood, CW Levy, ...
Journal of Inorganic Biochemistry 188, 18-28, 2018
202018
Mutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4‐Oxalocrotonate Tautomerase More Effectively than Distant Mutations
M Rahimi, JY van der Meer, EM Geertsema, H Poddar, BJ Baas, ...
ChemBioChem 17 (13), 1225-1228, 2016
182016
Towards engineering and production of artificial spider silk using tools of synthetic biology
H Poddar, R Breitling, E Takano
Engineering Biology 4 (1), 1-6, 2020
172020
Functional and structural characterization of an unusual cofactor-independent oxygenase
BJ Baas, H Poddar, EM Geertsema, HJ Rozeboom, MP de Vries, ...
Biochemistry 54 (5), 1219-1232, 2015
162015
WH; Poelarends, GJ Evidence for the Formation of an Enamine Species During Aldol and Michael-Type Addition Reactions Promiscuously Catalyzed by 4-Oxalocrotonate Tautomerase
H Poddar, M Rahimi, EM Geertsema, AM Thunnissen
Chem-BioChem 16, 738-741, 2015
72015
An unusual light-sensing function for coenzyme B12 in bacterial transcription regulator CarH
H Poddar, DJ Heyes, S Zhang, SJ Hardman, M Sakuma, NS Scrutton
Methods in Enzymology 668, 349-372, 2022
22022
Redox driven B12-ligand switch drives CarH photoresponse
H Poddar, R Rios-Santacruz, DJ Heyes, M Shanmugam, A Brookfield, ...
Nature Communications 14 (1), 5082, 2023
12023
Corrigendum: Mutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4‐Oxalocrotonate Tautomerase More Effectively than Distant Mutations
M Rahimi, JY van der Meer, EM Geertsema, H Poddar, BJ Baas, ...
ChemBioChem 17 (13), 1290-1290, 2016
12016
Photocobilins integrate B12 and bilin photochemistry for enzyme control
S Zhang, LN Jeffreys, H Poddar, Y Yu, C Liu, K Patel, LO Johannissen, ...
Nature Communications 15 (1), 2740, 2024
2024
Photocobilins integrate B12 and bilin photochemistry for enzyme control
N Scrutton, S Zhang, H Poddar, Y Yu, C Liu, K Patel, L Jeffreys, L Zhu, ...
2023
Means and methods for synthesizing precursors of y-aminobutyric acid (gaba) analogs
GJ POELARENDS, L BIEWENGA, JY VAN DER MEER, H PODDAR, ...
EP Patent EP3,599,246, 2020
2020
Structural and functional characterization of tautomerase and aspartase/fumarase superfamily enzymes
H Poddar
2020
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Straipsniai 1–18