H Steven Wiley
H Steven Wiley
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Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome
SM Varnum, DN Streblow, ME Monroe, P Smith, KJ Auberry, ...
Journal of virology 78 (20), 10960-10966, 2004
The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation …
HJS Huang, M Nagane, CK Klingbeil, H Lin, R Nishikawa, XD Ji, ...
Journal of Biological Chemistry 272 (5), 2927-2935, 1997
Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library
MJ Feldhaus, RW Siegel, LK Opresko, JR Coleman, JMW Feldhaus, ...
Nature biotechnology 21 (2), 163-170, 2003
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor
A Wells, JB Welsh, CS Lazar, HS Wiley, GN Gill, MG Rosenfeld
Science 247 (4945), 962-964, 1990
Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking
P Burke, K Schooler, HS Wiley
Molecular biology of the cell 12 (6), 1897-1910, 2001
Trafficking of the ErbB receptors and its influence on signaling
HS Wiley
The EGF Receptor Family, 81-91, 2003
The endocytotic rate constant. A cellular parameter for quantitating receptor-mediated endocytosis.
HS Wiley, DD Cunningham
Journal of Biological Chemistry 257 (8), 4222-4229, 1982
ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors
R Worthylake, LK Opresko, HS Wiley
Journal of Biological Chemistry 274 (13), 8865-8874, 1999
Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation
WS Chen, CS Lazar, KA Lund, JB Welsh, CP Chang, GM Walton, CJ Der, ...
Cell 59 (1), 33-43, 1989
Computational modeling of the EGF-receptor system: a paradigm for systems biology
HS Wiley, SY Shvartsman, DA Lauffenburger
Trends in cell biology 13 (1), 43-50, 2003
The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor
HS Wiley, JJ Herbst, BJ Walsh, DA Lauffenburger, MG Rosenfeld, GN Gill
Journal of Biological Chemistry 266 (17), 11083-11094, 1991
Regulation of receptor tyrosine kinase signaling by endocytic trafficking
HS Wiley, PM Burke
Traffic 2 (1), 12-18, 2001
Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor
J Dong, LK Opresko, PJ Dempsey, DA Lauffenburger, RJ Coffey, ...
Proceedings of the National Academy of Sciences 96 (11), 6235-6240, 1999
Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system.
HS Wiley
The Journal of cell biology 107 (2), 801-810, 1988
Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor
H Shankaran, DL Ippolito, WB Chrisler, H Resat, N Bollinger, LK Opresko, ...
Molecular systems biology 5 (1), 332, 2009
A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands
HS Wiley, DD Cunningham
Cell 25 (2), 433-440, 1981
Goldfish (Carassius auratus) vitellogenin: induction, isolation, properties and relationship to yolk proteins
VL de Vlaming, HS Wiley, G Delahunty, RA Wallace
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry 67 …, 1980
Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization.
KA Lund, LK Opresko, C Starbuck, BJ Walsh, HS Wiley
Journal of Biological Chemistry 265 (26), 15713-15723, 1990
Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo-and heterodimers depends on relative HER2 levels
BS Hendriks, LK Opresko, HS Wiley, D Lauffenburger
Journal of Biological Chemistry 278 (26), 23343-23351, 2003
An integrated model of epidermal growth factor receptor trafficking and signal transduction
H Resat, JA Ewald, DA Dixon, HS Wiley
Biophysical journal 85 (2), 730-743, 2003
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