Alessandro S. Nascimento
Alessandro S. Nascimento
Sao Carlos Institute of Physics, University of Sao Paulo
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Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) γ activators and pan-PPAR partial agonists
MV Liberato, AS Nascimento, SD Ayers, JZ Lin, A Cvoro, RL Silveira, ...
PloS one 7 (5), e36297, 2012
Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function
AS Nascimento, SMG Dias, FM Nunes, R Aparício, ALB Ambrosio, ...
Journal of molecular biology 360 (3), 586-598, 2006
Structural diversity of carbohydrate esterases
AM Nakamura, AS Nascimento, I Polikarpov
Biotechnology Research and Innovation 1 (1), 35-51, 2017
Gaining ligand selectivity in thyroid hormone receptors via entropy
L Martínez, AS Nascimento, FM Nunes, K Phillips, R Aparicio, SMG Dias, ...
Proceedings of the National Academy of Sciences 106 (49), 20717-20722, 2009
The MX2 macromolecular crystallography beamline: a wiggler X-ray source at the LNLS
BG Guimarães, L Sanfelici, RT Neuenschwander, F Rodrigues, ...
Journal of synchrotron radiation 16 (1), 69-75, 2009
Interleukin-22 forms dimers that are recognized by two interleukin-22R1 receptor chains
M de Oliveira Neto, JR Ferreira, D Colau, H Fischer, AS Nascimento, ...
Biophysical journal 94 (5), 1754-1765, 2008
Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia)
L Watanabe, PR de Moura, L Bleicher, AS Nascimento, LS Zamorano, ...
Journal of Structural Biology 169 (2), 226-242, 2010
Identification of a new hormone-binding site on the surface of thyroid hormone receptor
PCT Souza, AC Puhl, L Martínez, R Aparício, AS Nascimento, ...
Molecular endocrinology 28 (4), 534-545, 2014
Structural and biochemical characterization of a GH3 β-glucosidase from the probiotic bacteria Bifidobacterium adolescentis
RN Florindo, VP Souza, LR Manzine, CM Camilo, SR Marana, ...
Biochimie 148, 107-115, 2018
Structural insights into β-glucosidase transglycosylation based on biochemical, structural and computational analysis of two GH1 enzymes from Trichoderma harzianum
RN Florindo, VP Souza, HS Mutti, C Camilo, LR Manzine, SR Marana, ...
New biotechnology 40, 218-227, 2018
Catalytic mechanism of inulinase from Arthrobacter sp. S37
KY Kim, AS Nascimento, AM Golubev, I Polikarpov, CS Kim, SI Kang, ...
Biochemical and Biophysical Research Communications 371 (4), 600-605, 2008
An alternative conformation of ERβ bound to estradiol reveals H12 in a stable antagonist position
PCT Souza, LC Textor, DC Melo, AS Nascimento, MS Skaf, I Polikarpov
Scientific reports 7 (1), 3509, 2017
Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular …
L Bleicher, ET Prates, TCF Gomes, RL Silveira, AS Nascimento, AL Rojas, ...
The Journal of Physical Chemistry B 115 (24), 7940-7949, 2011
Structure-based virtual screening and discovery of new PPARδ/γ dual agonist and PPARδ and γ agonists
VG Maltarollo, M Togashi, AS Nascimento, KM Honorio
PloS one 10 (3), e0118790, 2015
Structure-based identification of novel PPAR gamma ligands
FMC da Silva, JC dos Santos, JLO Campos, AC Mafud, I Polikarpov, ...
Bioorganic & medicinal chemistry letters 23 (21), 5795-5802, 2013
Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+
AS Nascimento, DL Catalano-Dupuy, A Bernardes, MO Neto, ...
BMC structural biology 7, 1-12, 2007
MolShaCS: a free and open source tool for ligand similarity identification based on Gaussian descriptors
LACV de Lima, AS Nascimento
European journal of medicinal chemistry 59, 296-303, 2013
Crystal structure of β1→6‐galactosidase from Bifidobacterium bifidum S17: trimeric architecture, molecular determinants of the enzymatic activity and its inhibition …
AS Godoy, CM Camilo, MA Kadowaki, HS Muniz, M Espirito Santo, ...
The FEBS Journal 283 (22), 4097-4112, 2016
Insights into the structure and function of fungal β‐mannosidases from glycoside hydrolase family 2 based on multiple crystal structures of the Trichoderma harzianum enzyme
AS Nascimento, JRC Muniz, R Aparício, AM Golubev, I Polikarpov
The FEBS journal 281 (18), 4165-4178, 2014
Essential metabolic routes as a way to ESKAPE from antibiotic resistance
ALC Barra, LOC Dantas, LG Morão, RF Gutierrez, I Polikarpov, C Wrenger, ...
Frontiers in Public Health 8, 507951, 2020
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Articles 1–20