| Metabolism of non-enzymatically derived oxysterols: clues from sterol metabolic disorders WJ Griffiths, E Yutuc, J Abdel-Khalik, PJ Crick, T Hearn, A Dickson, ... Free Radical Biology and Medicine 144, 124-133, 2019 | 44 | 2019 |
| Identification of unusual oxysterols and bile acids with 7-oxo or 3β, 5α, 6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage … WJ Griffiths, I Gilmore, E Yutuc, J Abdel-Khalik, PJ Crick, T Hearn, ... Journal of lipid research 59 (6), 1058-1070, 2018 | 24 | 2018 |
| Charge-tagging liquid chromatography–mass spectrometry methodology targeting oxysterol diastereoisomers WJ Griffiths, T Hearn, PJ Crick, J Abdel-Khalik, A Dickson, E Yutuc, ... Chemistry and physics of lipids 207, 69-80, 2017 | 21 | 2017 |
| Deep mining of oxysterols and cholestenoic acids in human plasma and cerebrospinal fluid: Quantification using isotope dilution mass spectrometry E Yutuc, AL Dickson, M Pacciarini, L Griffiths, PRS Baker, L Connell, ... Analytica Chimica Acta 1154, 338259, 2021 | 18 | 2021 |
| Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates J Abdel-Khalik, T Hearn, AL Dickson, PJ Crick, E Yutuc, K Austin-Muttitt, ... The Journal of steroid biochemistry and molecular biology 206, 105794, 2021 | 17 | 2021 |
| Lipidomics basics WJ Griffiths, E Yutuc, D Davies, A Dickson, R Angelini, D El Assad, ... | 8 | 2020 |
| Identification of unusual oxysterols biosynthesised in human pregnancy by charge-tagging and liquid chromatography-mass spectrometry AL Dickson, E Yutuc, CA Thornton, Y Wang, WJ Griffiths Frontiers in Endocrinology 13, 1031013, 2022 | 5 | 2022 |
| The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent J Bré, AL Dickson, OJ Read, Y Zhang, FG McKissock, P Mullen, P Tang, ... Cancer Chemotherapy and Pharmacology 91 (5), 401-412, 2023 | 4 | 2023 |
| Human 2′-Deoxynucleoside 5′-Phosphate N-Hydrolase 1: Mechanism of 2′-Deoxyuridine 5′-Monophosphate Hydrolysis S Devi, AE Carberry, GM Zickuhr, AL Dickson, DJ Harrison, RG da Silva Biochemistry 62 (17), 2658-2668, 2023 | 3 | 2023 |
| Catalytic cycle of the bifunctional enzyme phosphoribosyl-ATP pyrophosphohydrolase/phosphoribosyl-AMP cyclohydrolase G Fisher, E Pečaver, BJ Read, SK Leese, E Laing, AL Dickson, ... ACS catalysis 13 (11), 7669-7679, 2023 | 3 | 2023 |
| HSD3B1 is an oxysterol 3β-hydroxysteroid dehydrogenase in human placenta A Dickson, E Yutuc, CA Thornton, JE Dunford, U Oppermann, Y Wang, ... Open biology 13 (5), 220313, 2023 | 3 | 2023 |
| Exposing the heterogeneity of the lipidome in the TME of cutaneous melanoma following treatment with NUC-7738 in combination with anti-PD-1 therapy AL Dickson, GM Zickuhr, IH Um, Y Zhang, R Plummer, SP Blagden, ... Cancer Research 84 (6_Supplement), 6222-6222, 2024 | | 2024 |
| RNA regulatory disruption by 3’-dATP: A novel approach to inhibit ribosome biogenesis in cancer M Elshani, Y Zhang, IH Um, R Plummer, SP Blagden, SN Symeonides, ... Cancer Research 84 (6_Supplement), 5650-5650, 2024 | | 2024 |
| Snapshots of the Reaction Coordinate of a Thermophilic 2′-Deoxyribonucleoside/ribonucleoside Transferase P Tang, CJ Harding, AL Dickson, RG da Silva, DJ Harrison, CM Czekster ACS Catalysis 14, 3090-3102, 2024 | | 2024 |
| Abstract C032: NUC-7738 in combination with pembrolizumab in patients with metastatic melanoma: Phase 2 results from the NuTide: 701 study SP Blagden, SN Symeonides, A Skolariki, NM Haris, Z Boh, IH Um, ... Molecular Cancer Therapeutics 22 (12_Supplement), C032-C032, 2023 | | 2023 |
| NUC-7738 promotes alternative polyadenylation site usage and reduces glutaminase GAC isoform M Elshani, Y Zhang, T Hawkins, M Kudsy, IH Um, G Zickuhr, AL Dickson, ... Cancer Research 83 (7_Supplement), 277-277, 2023 | | 2023 |
| NUC-7738 causes reduction of soluble and exosome-associated PD-L1 in melanoma cell lines and patients M Elshani, Y Zhang, B Kaghazchi, AL Dickson, SP Blagden, ... Cancer Research 83 (7_Supplement), 5962-5962, 2023 | | 2023 |
| Spatial Metabolomics co-registered with Multiplex Phenotyping for the Evaluation of Human Kidney Tissue GM Zickuhr, IH Um, A Laird, DJ Harrison, AL Dickson bioRxiv, 2023.11. 10.566529, 2023 | | 2023 |
| NUC-3373 is a potent TS inhibitor and induces DNA damage in NSCLC cancer cells regardless of histological subtype B Kaghazchi, AL Dickson, G Zickuhr, DJ Harrison, J Bré European Journal of Cancer 174, S66, 2022 | | 2022 |
| NUC-3373 targets the DNA-directed pathway more effectively than 5-FU J Bré, AL Dickson, OJ Read, Y Zhang, CM Czekster, DJ Harrison Cancer Research 82 (12_Supplement), 1835-1835, 2022 | | 2022 |
