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Antonio Currais
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Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in A lzheimer's disease transgenic mice
A Currais, M Prior, R Dargusch, A Armando, J Ehren, D Schubert, ...
Aging cell 13 (2), 379-390, 2014
1972014
The mitochondrial ATP synthase is a shared drug target for aging and dementia
J Goldberg, A Currais, M Prior, W Fischer, C Chiruta, E Ratliff, ...
Aging cell 17 (2), e12715, 2018
1372018
The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease
A Currais, T Hortobágyi, S Soriano
Aging 1 (4), 363, 2009
1342009
Functional consequences of age-dependent changes in glutathione status in the brain
A Currais, P Maher
Antioxidants & redox signaling 19 (8), 813-822, 2013
1172013
Fisetin reduces the impact of aging on behavior and physiology in the rapidly aging SAMP8 mouse
A Currais, C Farrokhi, R Dargusch, A Armando, O Quehenberger, ...
The journals of gerontology: series A 73 (3), 299-307, 2018
1082018
Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the aging brain
A Currais, W Fischer, P Maher, D Schubert
The FASEB Journal 31 (1), 5, 2017
1042017
Ageing and inflammation–a central role for mitochondria in brain health and disease
A Currais
Ageing Research Reviews 21, 30-42, 2015
1022015
Back to the future with phenotypic screening
M Prior, C Chiruta, A Currais, J Goldberg, J Ramsey, R Dargusch, ...
ACS Chemical Neuroscience 5 (7), 503-513, 2014
1002014
Elevating acetyl-CoA levels reduces aspects of brain aging
A Currais, L Huang, J Goldberg, M Petrascheck, G Ates, A Pinto-Duarte, ...
Elife 8, e47866, 2019
962019
CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's …
G Ates, J Goldberg, A Currais, P Maher
Redox Biology 36, 101648, 2020
852020
A comprehensive multiomics approach toward understanding the relationship between aging and dementia
A Currais, J Goldberg, C Farrokhi, M Chang, M Prior, R Dargusch, ...
Aging (Albany NY) 7 (11), 937, 2015
822015
Loss of neuronal cell cycle control as a mechanism of neurodegeneration in the presenilin-1 Alzheimer's disease brain
B Malik, A Currais, A Andres, C Towlson, D Pitsi, A Nunes, M Niblock, ...
Cell Cycle 7 (5), 637-646, 2008
812008
Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids
A Currais, O Quehenberger, A M Armando, D Daugherty, P Maher, ...
NPJ aging and mechanisms of disease 2 (1), 1-8, 2016
752016
Intracellular amyloid toxicity induces oxytosis/ferroptosis regulated cell death
L Huang, DB McClatchy, P Maher, Z Liang, JK Diedrich, ...
Cell death & disease 11 (10), 828, 2020
742020
Diabetes exacerbates amyloid and neurovascular pathology in aging‐accelerated mice
A Currais, M Prior, D Lo, C Jolivalt, D Schubert, P Maher
Aging cell 11 (6), 1017-1026, 2012
732012
MECP2 coding sequence and 3′ UTR variation in 172 unrelated autistic patients
AM Coutinho, G Oliveira, C Katz, J Feng, J Yan, C Yang, C Marques, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144 …, 2007
702007
Using the oxytosis/ferroptosis pathway to understand and treat age-associated neurodegenerative diseases
P Maher, A Currais, D Schubert
Cell chemical biology 27 (12), 1456-1471, 2020
682020
Old age-associated phenotypic screening for Alzheimer's disease drug candidates identifies sterubin as a potent neuroprotective compound from Yerba santa
W Fischer, A Currais, Z Liang, A Pinto, P Maher
Redox Biology 21, 101089, 2019
632019
Screening and identification of neuroprotective compounds relevant to Alzheimer׳ s disease from medicinal plants of S. Tomé e Príncipe
A Currais, C Chiruta, M Goujon-Svrzic, G Costa, T Santos, MT Batista, ...
Journal of ethnopharmacology 155 (1), 830-840, 2014
542014
Dietary glycemic index modulates the behavioral and biochemical abnormalities associated with autism spectrum disorder
A Currais, C Farrokhi, R Dargusch, M Goujon-Svrzic, P Maher
Molecular psychiatry 21 (3), 426-436, 2016
412016
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Articles 1–20