| Mechanism matters: a taxonomy of cell penetrating peptides WB Kauffman, T Fuselier, J He, WC Wimley Trends in biochemical sciences 40 (12), 749-764, 2015 | 374 | 2015 |
| Gain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening AJ Krauson, J He, WC Wimley Journal of the American Chemical Society 134 (30), 12732-12741, 2012 | 114 | 2012 |
| Investigating molecular recognition and biological function at interfaces using piscidins, antimicrobial peptides from fish EY Chekmenev, BS Vollmar, KT Forseth, MKN Manion, SM Jones, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (9), 1359-1372, 2006 | 103 | 2006 |
| Host cell interactions are a significant barrier to the clinical utility of peptide antibiotics CG Starr, J He, WC Wimley ACS chemical biology 11 (12), 3391-3399, 2016 | 100 | 2016 |
| Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers AJ Krauson, J He, WC Wimley Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (7), 1625-1632, 2012 | 81 | 2012 |
| Highly efficient macromolecule-sized poration of lipid bilayers by a synthetically evolved peptide G Wiedman, T Fuselier, J He, PC Searson, K Hristova, WC Wimley Journal of the American Chemical Society 136 (12), 4724-4731, 2014 | 80 | 2014 |
| Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides J He, WB Kauffman, T Fuselier, SK Naveen, TG Voss, K Hristova, ... Journal of Biological Chemistry 288 (41), 29974-29986, 2013 | 69 | 2013 |
| Pituitary adenylate cyclase-activating polypeptide is a potent broad-spectrum antimicrobial peptide: Structure-activity relationships CG Starr, JL Maderdrut, J He, DH Coy, WC Wimley Peptides 104, 35-40, 2018 | 59 | 2018 |
| A lack of synergy between membrane-permeabilizing cationic antimicrobial peptides and conventional antibiotics J He, CG Starr, WC Wimley Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (1), 8-15, 2015 | 59 | 2015 |
| Ebola virus delta peptide is a viroporin J He, LI Melnik, A Komin, G Wiedman, T Fuselier, CF Morris, CG Starr, ... Journal of virology 91 (16), 10.1128/jvi. 00438-17, 2017 | 53 | 2017 |
| An outbreak of Ebola virus disease in the Lassa fever zone A Goba, SH Khan, M Fonnie, M Fullah, A Moigboi, A Kovoma, V Sinnah, ... The Journal of infectious diseases 214 (suppl_3), S110-S121, 2016 | 44 | 2016 |
| Synthetic molecular evolution of pore-forming peptides by iterative combinatorial library screening AJ Krauson, J He, AW Wimley, AR Hoffmann, WC Wimley ACS chemical biology 8 (4), 823-831, 2013 | 39 | 2013 |
| Toward the de novo design of antimicrobial peptides: Lack of correlation between peptide permeabilization of lipid vesicles and antimicrobial, cytolytic, or cytotoxic activity … J He, AJ Krauson, WC Wimley Peptide Science 102 (1), 1-6, 2014 | 37 | 2014 |
| A Highly Charged Voltage‐Sensor Helix Spontaneously Translocates across Membranes J He, K Hristova, WC Wimley Angewandte Chemie 124 (29), 7262-7265, 2012 | 32 | 2012 |
| Structural plasticity in the topology of the membrane-interacting domain of HIV-1 gp41 A Kyrychenko, JA Freites, J He, DJ Tobias, WC Wimley, AS Ladokhin Biophysical journal 106 (3), 610-620, 2014 | 28 | 2014 |
| Broad-spectrum antiviral entry inhibition by interfacially active peptides AR Hoffmann, S Guha, E Wu, J Ghimire, Y Wang, J He, RF Garry, ... Journal of Virology 94 (23), 10.1128/jvi. 01682-20, 2020 | 26 | 2020 |
| High glucose induces trafficking of prorenin receptor and stimulates profibrotic factors in the collecting duct VR Gogulamudi, DY Arita, CRT Bourgeois, J Jorgensen, J He, ... Scientific Reports 11 (1), 13815, 2021 | 8 | 2021 |
| A highly charged voltage sensor helix translocates spontaneously across membranes J He, K Hristova, WC Wimley Angewandte Chemie (International ed. in English) 51 (29), 7150, 2012 | 3 | 2012 |
| The Delta Peptide of Ebola Virus has Potent Viroporin Activity J He, L Melnik, A Komin, CG Starr, T Fuselier, G Wiedman, CF Morris, ... Biophysical Journal 112 (3), 185a, 2017 | 2 | 2017 |
| Discovering Novel Antimicrobial Peptides using High-Throughput Screening in the Presence of Human Erythrocytes CG Starr, J He, WC Wimley Biophysical Journal 112 (3), 382a, 2017 | 2 | 2017 |
William C. WimleyProfessor of Biochemistry and Molecular Biology, Tulane UniversityVerified email at tulane.edu
