Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10734 | 2021 |
PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression KHT Paraiso, Y Xiang, VW Rebecca, EV Abel, YA Chen, AC Munko, ... Cancer research 71 (7), 2750-2760, 2011 | 640 | 2011 |
Emerging strategies to effectively target autophagy in cancer VW Rebecca, RK Amaravadi Oncogene 35 (1), 1-11, 2016 | 274 | 2016 |
A brief history of melanoma: from mummies to mutations VW Rebecca, VK Sondak, KSM Smalley Melanoma research 22 (2), 114-122, 2012 | 225 | 2012 |
The HSP90 inhibitor XL888 overcomes BRAF inhibitor resistance mediated through diverse mechanisms KHT Paraiso, HE Haarberg, E Wood, VW Rebecca, YA Chen, Y Xiang, ... Clinical cancer research 18 (9), 2502-2514, 2012 | 189 | 2012 |
Pre-clinical modeling of cutaneous melanoma VW Rebecca, R Somasundaram, M Herlyn Nature communications 11 (1), 2858, 2020 | 188 | 2020 |
PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer VW Rebecca, MC Nicastri, C Fennelly, CI Chude, JS Barber-Rotenberg, ... Cancer discovery 9 (2), 220-229, 2019 | 187 | 2019 |
Fibroblasts contribute to melanoma tumor growth and drug resistance EH Flach, VW Rebecca, M Herlyn, KSM Smalley, ARA Anderson Molecular pharmaceutics 8 (6), 2039-2049, 2011 | 165 | 2011 |
A unified approach to targeting the lysosome's degradative and growth signaling roles VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ... Cancer discovery 7 (11), 1266-1283, 2017 | 163 | 2017 |
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts XY Woo, J Giordano, A Srivastava, ZM Zhao, MW Lloyd, R de Bruijn, ... Nature genetics 53 (1), 86-99, 2021 | 149 | 2021 |
Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy R Somasundaram, T Connelly, R Choi, H Choi, A Samarkina, L Li, ... Nature communications 12 (1), 346, 2021 | 123 | 2021 |
Changes in aged fibroblast lipid metabolism induce age-dependent melanoma cell resistance to targeted therapy via the fatty acid transporter FATP2 GM Alicea, VW Rebecca, AR Goldman, ME Fane, SM Douglass, ... Cancer discovery 10 (9), 1282-1295, 2020 | 89 | 2020 |
Stromal changes in the aged lung induce an emergence from melanoma dormancy ME Fane, Y Chhabra, GM Alicea, DA Maranto, SM Douglass, MR Webster, ... Nature 606 (7913), 396-405, 2022 | 81 | 2022 |
ER translocation of the MAPK pathway drives therapy resistance in BRAF-mutant melanoma R Ojha, NM Leli, A Onorati, S Piao, II Verginadis, F Tameire, VW Rebecca, ... Cancer discovery 9 (3), 396-415, 2019 | 75 | 2019 |
Inhibition of autophagy enhances the effects of the AKT inhibitor MK‐2206 when combined with paclitaxel and carboplatin in BRAF wild‐type melanoma VW Rebecca, RR Massaro, IV Fedorenko, VK Sondak, ARA Anderson, ... Pigment cell & melanoma research 27 (3), 465-478, 2014 | 75 | 2014 |
Inhibition of Wee1, AKT, and CDK4 Underlies the Efficacy of the HSP90 Inhibitor XL888 in an In Vivo Model of NRAS-Mutant Melanoma HE Haarberg, KHT Paraiso, E Wood, VW Rebecca, VK Sondak, ... Molecular cancer therapeutics 12 (6), 901-912, 2013 | 70 | 2013 |
Vertical inhibition of the MAPK pathway enhances therapeutic responses in NRAS‐mutant melanoma VW Rebecca, GM Alicea, KHT Paraiso, H Lawrence, GT Gibney, ... Pigment cell & melanoma research 27 (6), 1154-1158, 2014 | 63 | 2014 |
Evaluating melanoma drug response and therapeutic escape with quantitative proteomics VW Rebecca, E Wood, IV Fedorenko, KHT Paraiso, HE Haarberg, ... Molecular & Cellular Proteomics 13 (7), 1844-1854, 2014 | 62 | 2014 |
Paradoxical role for wild-type p53 in driving therapy resistance in melanoma MR Webster, ME Fane, GM Alicea, S Basu, AV Kossenkov, GE Marino, ... Molecular cell 77 (3), 633-644. e5, 2020 | 60 | 2020 |
Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach E Kim, V Rebecca, IV Fedorenko, JL Messina, R Mathew, ... Cancer research 73 (23), 6874-6885, 2013 | 59 | 2013 |