Tackling antibiotic resistance K Bush, P Courvalin, G Dantas, J Davies, B Eisenstein, P Huovinen, ... Nature Reviews Microbiology 9 (12), 894-896, 2011 | 1237 | 2011 |
Multidrug resistance mechanisms: drug efflux across two membranes HI Zgurskaya, H Nikaido Molecular microbiology 37 (2), 219-225, 2000 | 616 | 2000 |
Permeability barrier of Gram-negative cell envelopes and approaches to bypass it HI Zgurskaya, CA López, S Gnanakaran ACS infectious diseases 1 (11), 512-522, 2015 | 569 | 2015 |
Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump EW Yu, G McDermott, HI Zgurskaya, H Nikaido, DE Koshland Jr Science 300 (5621), 976-980, 2003 | 498 | 2003 |
Bypassing the periplasm: Reconstitution of the AcrAB multidrug efflux pump of Escherichia coli HI Zgurskaya, H Nikaido Proceedings of the National Academy of Sciences 96 (13), 7190-7195, 1999 | 477 | 1999 |
Conformational flexibility in the multidrug efflux system protein AcrA J Mikolosko, K Bobyk, HI Zgurskaya, P Ghosh Structure 14 (3), 577-587, 2006 | 357 | 2006 |
AcrA, AcrB, and TolC of Escherichia coli form a stable intermembrane multidrug efflux complex EB Tikhonova, HI Zgurskaya Journal of Biological Chemistry 279 (31), 32116-32124, 2004 | 341 | 2004 |
AcrAB and related multidrug efflux pumps of Escherichia coli H Nikaido, HI Zgurskaya Journal of molecular microbiology and biotechnology 3 (2), 215-218, 2001 | 304 | 2001 |
AcrA is a highly asymmetric protein capable of spanning the periplasm HI Zgurskaya, H Nikaido Journal of molecular biology 285 (1), 409-420, 1999 | 292 | 1999 |
Mechanism and function of the outer membrane channel TolC in multidrug resistance and physiology of enterobacteria HI Zgurskaya, G Krishnamoorthy, A Ntreh, S Lu Frontiers in microbiology 2, 189, 2011 | 237 | 2011 |
Chimeric analysis of the multicomponent multidrug efflux transporters from gram-negative bacteria EB Tikhonova, Q Wang, HI Zgurskaya Journal of bacteriology 184 (23), 6499-6507, 2002 | 226 | 2002 |
Waltzing transporters and'the dance macabre'between humans and bacteria O Lomovskaya, HI Zgurskaya, M Totrov, WJ Watkins Nature reviews Drug discovery 6 (1), 56-65, 2007 | 219 | 2007 |
Cross-Linked Complex between Oligomeric Periplasmic Lipoprotein AcrA and the Inner-Membrane-Associated Multidrug Efflux Pump AcrB from Escherichia coli HI Zgurskaya, H Nikaido Journal of bacteriology 182 (15), 4264-4267, 2000 | 212 | 2000 |
Synergy between active efflux and outer membrane diffusion defines rules of antibiotic permeation into Gram-negative bacteria G Krishnamoorthy, IV Leus, JW Weeks, D Wolloscheck, VV Rybenkov, ... MBio 8 (5), 10.1128/mbio. 01172-17, 2017 | 166 | 2017 |
Sequential mechanism of assembly of multidrug efflux pump AcrAB-TolC EB Tikhonova, Y Yamada, HI Zgurskaya Chemistry & biology 18 (4), 454-463, 2011 | 147 | 2011 |
Rathayibacter gen. nov., Including the Species Rathayibacter rathayi comb. nov., Rathayibacter tritici comb. nov., Rathayibacter iranicus comb. nov., and Six … HI Zgurskaya, LI Evtushenko, VN Akimov, LV Kalakoutskii International Journal of Systematic and Evolutionary Microbiology 43 (1 …, 1993 | 138 | 1993 |
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB EB Tikhonova, VK Devroy, SY Lau, HI Zgurskaya Molecular microbiology 63 (3), 895-910, 2007 | 131 | 2007 |
Breaking the permeability barrier of Escherichia coli by controlled hyperporination of the outer membrane G Krishnamoorthy, D Wolloscheck, JW Weeks, C Croft, VV Rybenkov, ... Antimicrobial agents and chemotherapy 60 (12), 7372-7381, 2016 | 126 | 2016 |
Reviving antibiotics: efflux pump inhibitors that interact with AcrA, a membrane fusion protein of the AcrAB-TolC multidrug efflux pump N Abdali, JM Parks, KM Haynes, JL Chaney, AT Green, D Wolloscheck, ... ACS infectious diseases 3 (1), 89-98, 2017 | 108 | 2017 |
Kinetic control of TolC recruitment by multidrug efflux complexes EB Tikhonova, V Dastidar, VV Rybenkov, HI Zgurskaya Proceedings of the National Academy of Sciences 106 (38), 16416-16421, 2009 | 105 | 2009 |