Stebėti
Tautvydas Karvelis
Tautvydas Karvelis
Institute of Biotechnology, Life Sciences Center, Vilnius University
Patvirtintas el. paštas bti.vu.lt
Pavadinimas
Cituota
Cituota
Metai
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
MD Szczelkun, MS Tikhomirova, T Sinkunas, G Gasiunas, T Karvelis, ...
Proceedings of the National Academy of Sciences 111 (27), 9798-9803, 2014
4252014
crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus
T Karvelis, G Gasiunas, A Miksys, R Barrangou, P Horvath, V Siksnys
RNA biology 10 (5), 841-851, 2013
3012013
RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX
V Siksnys, G Gasiunas, T Karvelis, A Lubys, L Zaliauskiene, M Glemzaite, ...
US Patent App. 14/385,857, 2015
2112015
RNA-directed DNA cleavage by the Cas9-crRNA complex
G Gasiunas, T Karvelis
US Patent 9,637,739, 2017
2002017
Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements
T Karvelis, G Gasiunas, J Young, G Bigelyte, A Silanskas, M Cigan, ...
Genome biology 16 (1), 1-13, 2015
1872015
PAM recognition by miniature CRISPR–Cas12f nucleases triggers programmable double-stranded DNA target cleavage
T Karvelis, G Bigelyte, JK Young, Z Hou, R Zedaveinyte, K Budre, ...
Nucleic acids research 48 (9), 5016-5023, 2020
1082020
RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX
V Siksnys, G Gasiunas, T Karvelis
US Patent App. 14/743,764, 2015
962015
RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX
V Siksnys, G Gasiünas, T Karvelis
US Patent App. 14/683,443, 2015
862015
A catalogue of biochemically diverse CRISPR-Cas9 orthologs
G Gasiunas, JK Young, T Karvelis, D Kazlauskas, T Urbaitis, ...
Nature communications 11 (1), 1-10, 2020
722020
RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX
V Siksnys, G Gasiunas, T Karvelis, A Lubys, L Zaliauskiene, M Glemzaite, ...
US Patent App. 15/834,578, 2018
572018
RNA-directed DNA cleavage by the Cas9-crRNA complex
G Gasiūnas, T Karvelis
US Patent 10,844,378, 2020
472020
Programmable DNA cleavage in vitro by Cas9
T Karvelis, G Gasiunas, V Siksnys
Biochemical Society Transactions 41 (6), 1401-1406, 2013
432013
Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease
T Karvelis, G Druteika, G Bigelyte, K Budre, R Zedaveinyte, A Silanskas, ...
Nature 599 (7886), 692-696, 2021
382021
Methods for decoding Cas9 protospacer adjacent motif (PAM) sequences: a brief overview
T Karvelis, G Gasiunas, V Siksnys
Methods 121, 3-8, 2017
302017
Harnessing the natural diversity and in vitro evolution of Cas9 to expand the genome editing toolbox
T Karvelis, G Gasiunas, V Siksnys
Current Opinion in Microbiology 37, 88-94, 2017
282017
Targeted gene editing by transfection of in vitro reconstituted Streptococcus thermophilus Cas9 nuclease complex
M Glemzaite, E Balciunaite, T Karvelis, G Gasiunas, MM Grusyte, ...
RNA biology 12 (1), 1-4, 2015
252015
Miniature type VF CRISPR-Cas nucleases enable targeted DNA modification in cells
G Bigelyte, JK Young, T Karvelis, K Budre, R Zedaveinyte, V Djukanovic, ...
Nature communications 12 (1), 1-8, 2021
202021
5′ modifications to CRISPR–Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage
G Mullally, K Van Aelst, MM Naqvi, FM Diffin, T Karvelis, G Gasiunas, ...
Nucleic acids research 48 (12), 6811-6823, 2020
172020
A pipeline for characterization of novel Cas9 orthologs
T Karvelis, JK Young, V Siksnys
Academic Press, 2019
132019
Oriented soft DNA curtains for single-molecule imaging
A Kopu̅stas, S Ivanovaitė, T Rakickas, E Pocevičiu̅tė, J Paksaitė, ...
Langmuir 37 (11), 3428-3437, 2021
52021
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