Prognostic gene expression signature for high-grade serous ovarian cancer J Millstein, T Budden, EL Goode, MS Anglesio, A Talhouk, ... Annals of oncology 31 (9), 1240-1250, 2020 | 105 | 2020 |
The molecular mechanism of eukaryotic elongation factor 2 kinase activation CDJ Tavares, SB Ferguson, DH Giles, Q Wang, RM Wellmann, JP O'Brien, ... Journal of Biological Chemistry 289 (34), 23901-23916, 2014 | 41 | 2014 |
MyD88 and TLR4 expression in epithelial ovarian cancer MS Block, RA Vierkant, PF Rambau, SJ Winham, P Wagner, N Traficante, ... Mayo Clinic Proceedings 93 (3), 307-320, 2018 | 37 | 2018 |
Structural evaluation of protein/metal complexes via native electrospray ultraviolet photodissociation mass spectrometry CM Crittenden, ET Novelli, MR Mehaffey, GN Xu, DH Giles, WA Fies, ... Journal of the American Society for Mass Spectrometry 31 (5), 1140-1150, 2020 | 22 | 2020 |
Structural basis for the recognition of eukaryotic elongation factor 2 kinase by calmodulin K Lee, S Alphonse, A Piserchio, CDJ Tavares, DH Giles, RM Wellmann, ... Structure 24 (9), 1441-1451, 2016 | 22 | 2016 |
Signal integration at elongation factor 2 kinase: The roles of calcium, calmodulin, and SER-500 phosphorylation CDJ Tavares, DH Giles, G Stancu, CA Chitjian, SB Ferguson, ... Journal of Biological Chemistry 292 (5), 2032-2045, 2017 | 18 | 2017 |
Structural dynamics of the activation of elongation factor 2 kinase by Ca2+-calmodulin N Will, K Lee, F Hajredini, DH Giles, RR Abzalimov, M Clarkson, ... Journal of molecular biology 430 (17), 2802-2821, 2018 | 17 | 2018 |
Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylase SC Daubner, A Avila, JO Bailey, D Barrera, JY Bermudez, DH Giles, ... Biochemistry 52 (8), 1446-1455, 2013 | 12 | 2013 |
Solution structure of the carboxy-terminal tandem repeat domain of eukaryotic elongation factor 2 kinase and its role in substrate recognition A Piserchio, N Will, DH Giles, F Hajredini, KN Dalby, R Ghose Journal of molecular biology 431 (15), 2700-2717, 2019 | 9 | 2019 |
Structure of the C-Terminal helical repeat domain of eukaryotic elongation factor 2 Kinase N Will, A Piserchio, I Snyder, SB Ferguson, DH Giles, KN Dalby, R Ghose Biochemistry 55 (38), 5377-5386, 2016 | 7 | 2016 |
Copy number variants are ovarian cancer risk alleles at known and novel risk loci AA DeVries, J Dennis, JP Tyrer, PC Peng, SG Coetzee, AL Reyes, ... JNCI: Journal of the National Cancer Institute 114 (11), 1533-1544, 2022 | 6 | 2022 |
The Australian Ovarian Cancer Study N Traficante, S Fereday, L Galletta, J Hung, D Giles, K Alsop, J Hendley, ... Hereditary Cancer in Clinical Practice 10, 1-2, 2012 | 2 | 2012 |
Dynamic equilibrium of eEF‐2K and CaM as a regulatory logic circuit: investigations in MCF10A cells KN Dalby, DH Giles, CM Crittenden, TS Kaoud, R Ghose, J Brodbelt The FASEB Journal 32, 526.14-526.14, 2018 | | 2018 |
Molecular signal processing by eukaryotic elongation factor 2 kinase (eEF-2K) DH Giles | | 2018 |
Mechanism of the AMPK-dependent activation of eukaryotic elongation factor 2 kinase (eEF-2K) DH Giles, CM Crittenden, JS Brodbelt, KN Dalby Cancer Research 76 (14_Supplement), 193-193, 2016 | | 2016 |
Modulation of eukaryotic elongation factor 2 kinase activity via phosphorylation on Ser‐500 (773.1) C Tavares, T Kaoud, S Ferguson, R Wellmann, B Stancu, D Giles, ... The FASEB Journal 28, 773.1, 2014 | | 2014 |
Full wwPDB NMR Structure Validation Report i○ S Alphonse, K Lee, A Piserchio, CDJ Tavares, DH Giles | | |