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David H. Giles
David H. Giles
Verified email at utexas.edu
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Cited by
Cited by
Year
Prognostic gene expression signature for high-grade serous ovarian cancer
J Millstein, T Budden, EL Goode, MS Anglesio, A Talhouk, ...
Annals of oncology 31 (9), 1240-1250, 2020
1052020
The molecular mechanism of eukaryotic elongation factor 2 kinase activation
CDJ Tavares, SB Ferguson, DH Giles, Q Wang, RM Wellmann, JP O'Brien, ...
Journal of Biological Chemistry 289 (34), 23901-23916, 2014
412014
MyD88 and TLR4 expression in epithelial ovarian cancer
MS Block, RA Vierkant, PF Rambau, SJ Winham, P Wagner, N Traficante, ...
Mayo Clinic Proceedings 93 (3), 307-320, 2018
372018
Structural evaluation of protein/metal complexes via native electrospray ultraviolet photodissociation mass spectrometry
CM Crittenden, ET Novelli, MR Mehaffey, GN Xu, DH Giles, WA Fies, ...
Journal of the American Society for Mass Spectrometry 31 (5), 1140-1150, 2020
222020
Structural basis for the recognition of eukaryotic elongation factor 2 kinase by calmodulin
K Lee, S Alphonse, A Piserchio, CDJ Tavares, DH Giles, RM Wellmann, ...
Structure 24 (9), 1441-1451, 2016
222016
Signal integration at elongation factor 2 kinase: The roles of calcium, calmodulin, and SER-500 phosphorylation
CDJ Tavares, DH Giles, G Stancu, CA Chitjian, SB Ferguson, ...
Journal of Biological Chemistry 292 (5), 2032-2045, 2017
182017
Structural dynamics of the activation of elongation factor 2 kinase by Ca2+-calmodulin
N Will, K Lee, F Hajredini, DH Giles, RR Abzalimov, M Clarkson, ...
Journal of molecular biology 430 (17), 2802-2821, 2018
172018
Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylase
SC Daubner, A Avila, JO Bailey, D Barrera, JY Bermudez, DH Giles, ...
Biochemistry 52 (8), 1446-1455, 2013
122013
Solution structure of the carboxy-terminal tandem repeat domain of eukaryotic elongation factor 2 kinase and its role in substrate recognition
A Piserchio, N Will, DH Giles, F Hajredini, KN Dalby, R Ghose
Journal of molecular biology 431 (15), 2700-2717, 2019
92019
Structure of the C-Terminal helical repeat domain of eukaryotic elongation factor 2 Kinase
N Will, A Piserchio, I Snyder, SB Ferguson, DH Giles, KN Dalby, R Ghose
Biochemistry 55 (38), 5377-5386, 2016
72016
Copy number variants are ovarian cancer risk alleles at known and novel risk loci
AA DeVries, J Dennis, JP Tyrer, PC Peng, SG Coetzee, AL Reyes, ...
JNCI: Journal of the National Cancer Institute 114 (11), 1533-1544, 2022
62022
The Australian Ovarian Cancer Study
N Traficante, S Fereday, L Galletta, J Hung, D Giles, K Alsop, J Hendley, ...
Hereditary Cancer in Clinical Practice 10, 1-2, 2012
22012
Dynamic equilibrium of eEF‐2K and CaM as a regulatory logic circuit: investigations in MCF10A cells
KN Dalby, DH Giles, CM Crittenden, TS Kaoud, R Ghose, J Brodbelt
The FASEB Journal 32, 526.14-526.14, 2018
2018
Molecular signal processing by eukaryotic elongation factor 2 kinase (eEF-2K)
DH Giles
2018
Mechanism of the AMPK-dependent activation of eukaryotic elongation factor 2 kinase (eEF-2K)
DH Giles, CM Crittenden, JS Brodbelt, KN Dalby
Cancer Research 76 (14_Supplement), 193-193, 2016
2016
Modulation of eukaryotic elongation factor 2 kinase activity via phosphorylation on Ser‐500 (773.1)
C Tavares, T Kaoud, S Ferguson, R Wellmann, B Stancu, D Giles, ...
The FASEB Journal 28, 773.1, 2014
2014
Full wwPDB NMR Structure Validation Report i○
S Alphonse, K Lee, A Piserchio, CDJ Tavares, DH Giles
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Articles 1–17