|High-throughput screening assays for the identification of chemical probes|
J Inglese, RL Johnson, A Simeonov, M Xia, W Zheng, CP Austin, DS Auld
Nature chemical biology 3 (8), 466-479, 2007
|Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen|
M Xu, EM Lee, Z Wen, Y Cheng, WK Huang, X Qian, J Tcw, ...
Nature medicine 22 (10), 1101-1107, 2016
|Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors|
A Singh, S Venkannagari, KH Oh, YQ Zhang, JM Rohde, L Liu, ...
ACS chemical biology 11 (11), 3214-3225, 2016
|Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action|
SC Miller, R Huang, S Sakamuru, SJ Shukla, MS Attene-Ramos, P Shinn, ...
Biochemical pharmacology 79 (9), 1272-1280, 2010
|Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead|
WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ...
Carcinogenesis 36 (Suppl_1), S254-S296, 2015
|Compound cytotoxicity profiling using quantitative high-throughput screening|
M Xia, R Huang, KL Witt, N Southall, J Fostel, MH Cho, A Jadhav, ...
Environmental health perspectives 116 (3), 284-291, 2008
|The future of toxicity testing: a focus on in vitro methods using a quantitative high-throughput screening platform|
SJ Shukla, R Huang, CP Austin, M Xia
Drug discovery today 15 (23-24), 997-1007, 2010
|5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary|
T Khare, S Pai, K Koncevicius, M Pal, E Kriukiene, Z Liutkeviciute, M Irimia, ...
Nature structural & molecular biology 19 (10), 1037-1043, 2012
|Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor|
RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ...
Toxicological Sciences 148 (1), 137-154, 2015
|Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space|
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
|Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity|
RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ...
Environmental science & technology 44 (15), 5979-5985, 2010
|Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane.|
M Xia, D Leppert, SL Hauser, SP Sreedharan, PJ Nelson, AM Krensky, ...
Journal of immunology (Baltimore, Md.: 1950) 156 (1), 160-167, 1996
|The Tox21 robotic platform for the assessment of environmental chemicals–from vision to reality|
MS Attene-Ramos, N Miller, R Huang, S Michael, M Itkin, RJ Kavlock, ...
Drug discovery today 18 (15-16), 716-723, 2013
|Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2|
SZ An, JH Yang, MH Xia, EJ Goetzl
Biochemical and biophysical research communications 197 (1), 263-270, 1993
|Chemical genomics profiling of environmental chemical modulation of human nuclear receptors|
R Huang, M Xia, MH Cho, S Sakamuru, P Shinn, KA Houck, DJ Dix, ...
Environmental health perspectives 119 (8), 1142-1148, 2011
|Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization|
R Huang, M Xia, S Sakamuru, J Zhao, SA Shahane, M Attene-Ramos, ...
Nature communications 7 (1), 10425, 2016
|Bisphenol A affects androgen receptor function via multiple mechanisms|
C Teng, B Goodwin, K Shockley, M Xia, R Huang, J Norris, BA Merrick, ...
Chemico-biological interactions 203 (3), 556-564, 2013
|Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals|
ATJ Murk, E Rijntjes, BJ Blaauboer, R Clewell, KM Crofton, ...
Toxicology in vitro 27 (4), 1320-1346, 2013
|Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction|
Z Li, M Brecher, YQ Deng, J Zhang, S Sakamuru, B Liu, R Huang, ...
Cell research 27 (8), 1046-1064, 2017
|Mitochondrial membrane potential assay|
S Sakamuru, MS Attene-Ramos, M Xia
High-throughput screening assays in toxicology, 17-22, 2016