Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital A Ueda, HK Hamadeh, HK Webb, Y Yamamoto, T Sueyoshi, CA Afshari, ... Molecular pharmacology 61 (1), 1-6, 2002 | 540 | 2002 |
Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes S Kodama, C Koike, M Negishi, Y Yamamoto Molecular and cellular biology 24 (18), 7931-7940, 2004 | 403 | 2004 |
The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice Y Yamamoto, R Moore, TL Goldsworthy, M Negishi, RR Maronpot Cancer research 64 (20), 7197-7200, 2004 | 387 | 2004 |
Estrogen receptor α mediates 17α-ethynylestradiol causing hepatotoxicity Y Yamamoto, R Moore, HA Hess, GL Guo, FJ Gonzalez, KS Korach, ... Journal of Biological Chemistry 281 (24), 16625-16631, 2006 | 214 | 2006 |
Melanocortin 4 receptor–deficient mice as a novel mouse model of nonalcoholic steatohepatitis M Itoh, T Suganami, N Nakagawa, M Tanaka, Y Yamamoto, Y Kamei, ... The American journal of pathology 179 (5), 2454-2463, 2011 | 172 | 2011 |
Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene S Kodama, R Moore, Y Yamamoto, M Negishi Biochemical Journal 407 (3), 373-381, 2007 | 150 | 2007 |
In vivo and in vitro inhibition of monocyte adhesion to endothelial cells and endothelial adhesion molecules by eicosapentaenoic acid H Yamada, M Yoshida, Y Nakano, T Suganami, N Satoh, T Mita, K Azuma, ... Arteriosclerosis, thrombosis, and vascular biology 28 (12), 2173-2179, 2008 | 134 | 2008 |
Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration GR Jeong, EH Jang, JR Bae, S Jun, HC Kang, CH Park, JH Shin, ... Molecular neurodegeneration 13, 1-17, 2018 | 114 | 2018 |
The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity Y Yamamoto, T Kawamoto, M Negishi Archives of biochemistry and biophysics 409 (1), 207-211, 2003 | 93 | 2003 |
Phenobarbital induction of drug/steroid-metabolizing enzymes and nuclear receptor CAR S Kakizaki, Y Yamamoto, A Ueda, R Moore, T Sueyoshi, M Negishi Biochimica et Biophysica Acta (BBA)-General Subjects 1619 (3), 239-242, 2003 | 83 | 2003 |
Triggering of neuronal cell death by accumulation of activated SEK1 on nuclear polyglutamine aggregations in PML bodies S Yasuda, K Inoue, M Hirabayashi, H Higashiyama, Y Yamamoto, ... Genes to Cells 4 (12), 743-756, 1999 | 75 | 1999 |
Novel CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells K Swales, S Kakizaki, Y Yamamoto, K Inoue, K Kobayashi, M Negishi Journal of biological chemistry 280 (5), 3458-3466, 2005 | 70 | 2005 |
Nuclear receptor CAR represses TNFα-induced cell death by interacting with the anti-apoptotic GADD45B Y Yamamoto, R Moore, RA Flavell, B Lu, M Negishi PLoS One 5 (4), e10121, 2010 | 69 | 2010 |
Orphan nuclear receptor constitutive active/androstane receptor–mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis JM Phillips, Y Yamamoto, M Negishi, RR Maronpot, JI Goodman Toxicological sciences 96 (1), 72-82, 2007 | 63 | 2007 |
Molecular basis of the Dark Agouti rat drug oxidation polymorphism: importance of CYP2D1 and CYP2D2 Y Yamamoto, T Tasaki, A Nakamura, H Iwata, A Kazusaka, FJ Gonzalez, ... Pharmacogenetics and Genomics 8 (1), 73-82, 1998 | 58 | 1998 |
Identification of novel cytochrome P450 1A genes from five marine mammal species I Teramitsu, Y Yamamoto, I Chiba, H Iwata, S Tanabe, Y Fujise, ... Aquatic Toxicology 51 (2), 145-153, 2000 | 55 | 2000 |
VTA-projecting cerebellar neurons mediate stress-dependent depression-like behaviors SJ Baek, JS Park, J Kim, Y Yamamoto, K Tanaka-Yamamoto Elife 11, e72981, 2022 | 45 | 2022 |
Raf kinase inhibitory protein is required for cerebellar long-term synaptic depression by mediating PKC-dependent MAPK activation Y Yamamoto, D Lee, Y Kim, B Lee, C Seo, H Kawasaki, S Kuroda, ... Journal of Neuroscience 32 (41), 14254-14264, 2012 | 31 | 2012 |
The antiapoptotic factor growth arrest and DNA-damage-inducible 45 β regulates the nuclear receptor constitutive active/androstane receptor-mediated transcription Y Yamamoto, M Negishi Drug metabolism and disposition 36 (7), 1189-1193, 2008 | 28 | 2008 |
Recent advances in the understanding of specific efferent pathways emerging from the cerebellum S Kang, S Jun, SJ Baek, H Park, Y Yamamoto, K Tanaka-Yamamoto Frontiers in Neuroanatomy 15, 759948, 2021 | 26 | 2021 |