Lymphocyte-derived exosomal microRNAs promote pancreatic β cell death and may contribute to type 1 diabetes development C Guay, JK Kruit, S Rome, V Menoud, NL Mulder, A Jurdzinski, ... Cell metabolism 29 (2), 348-361. e6, 2019 | 226 | 2019 |
Combined inhibition of DYRK1A, SMAD, and trithorax pathways synergizes to induce robust replication in adult human beta cells P Wang, E Karakose, H Liu, E Swartz, C Ackeifi, V Zlatanic, J Wilson, ... Cell metabolism 29 (3), 638-652. e5, 2019 | 148 | 2019 |
GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration Ackeifi C., Wang P., Karakose E., Manning Fox JE., González BJ., Liu H ... Science Translational Medicine 12 (530), 2020 | 110 | 2020 |
BRDT is an essential epigenetic regulator for proper chromatin organization, silencing of sex chromosomes and crossover formation in male meiosis M Manterola, TM Brown, MY Oh, C Garyn, BJ Gonzalez, DJ Wolgemuth PLoS genetics 14 (3), e1007209, 2018 | 64 | 2018 |
Induction of α cell–restricted Gc in dedifferentiating β cells contributes to stress-induced β cell dysfunction T Kuo, M Damle, BJ González, D Egli, MA Lazar, D Accili JCI insight 4 (13), 2019 | 31 | 2019 |
How safe are universal pluripotent stem cells? BJ González, RJ Creusot, M Sykes, D Egli Cell Stem Cell 26 (3), 307-308, 2020 | 15 | 2020 |
Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency BJ González, H Zhao, J Niu, DJ Williams, J Lee, CN Goulbourne, Y Xing, ... Communications Biology 5 (1), 779, 2022 | 14 | 2022 |
Human stem cell model of HNF1A deficiency shows uncoupled insulin to C-peptide secretion with accumulation of abnormal insulin granules BJ González, H Zhao, J Niu, DJ Williams, J Lee, CN Goulbourne, Y Xing, ... bioRxiv, 2021.01. 26.428260, 2021 | 9 | 2021 |
Compositions and methods for cell engineering for meat production NG Bryan J. Gonzalez, Gabor Forgacs WO Patent WO2023178084A2, 2023 | | 2023 |
HNF1A deficiency causes reduced calcium levels, accumulation of abnormal insulin granules and uncoupled insulin to C-peptide secretion in a stem cell model of MODY3 B Gonzalez, H Zhao, J Niu, D Williams, J Lee, C Goulbourne, Y Xing, ... | | 2021 |
HNF1A Deficiency Impairs β-Cell Fate, Granule Maturation and Function BJ Gonzalez Columbia University, 2019 | | 2019 |
P057 Cellules β dérivées à partir des iPSCs de patients avec MODY3 comme modèle du diabète dû à une déficience dans le gène HNF1a B Gonzalez, H Hua Diabetes & Metabolism 41, A47, 2015 | | 2015 |