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Carlos M Guardia
Carlos M Guardia
Head of the Placental Cell Biology Group, NIEHS/NIH, Durham (NC), USA
Verified email at nih.gov - Homepage
Title
Cited by
Cited by
Year
Mechanisms and functions of lysosome positioning
J Pu, CM Guardia, T Keren-Kaplan, JS Bonifacino
Journal of cell science 129 (23), 4329-4339, 2016
5012016
When galectins recognize glycans: from biochemistry to physiology and back again
S Di Lella, V Sundblad, JP Cerliani, CM Guardia, DA Estrin, GR Vasta, ...
Biochemistry 50 (37), 7842-7857, 2011
3352011
BORC functions upstream of kinesins 1 and 3 to coordinate regional movement of lysosomes along different microtubule tracks
CM Guardia, GG Farías, R Jia, J Pu, JS Bonifacino
Cell reports 17 (8), 1950-1961, 2016
2262016
BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon
GG Farías, CM Guardia, R De Pace, DJ Britt, JS Bonifacino
Proceedings of the National Academy of Sciences 114 (14), E2955-E2964, 2017
1982017
AP-4 mediates export of ATG9A from the trans-Golgi network to promote autophagosome formation
R Mattera, SY Park, R De Pace, CM Guardia, JS Bonifacino
Proceedings of the National Academy of Sciences 114 (50), E10697-E10706, 2017
1472017
BORC coordinates encounter and fusion of lysosomes with autophagosomes
R Jia, CM Guardia, J Pu, Y Chen, JS Bonifacino
Autophagy 13 (10), 1648-1663, 2017
1292017
Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery
CM Guardia, XF Tan, T Lian, MS Rana, W Zhou, ET Christenson, ...
Cell Reports 31 (13), 2020
1282020
Sorting of dendritic and axonal vesicles at the pre-axonal exclusion zone
GG Farías, CM Guardia, DJ Britt, X Guo, JS Bonifacino
Cell reports 13 (6), 1221-1232, 2015
1192015
A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis
G Sharma, CM Guardia, A Roy, A Vassilev, A Saric, LN Griner, J Marugan, ...
Autophagy 15 (10), 1694-1718, 2019
1022019
Neuronal functions of adaptor complexes involved in protein sorting
CM Guardia, R De Pace, R Mattera, JS Bonifacino
Current Opinion in Neurobiology 51, 103-110, 2018
682018
The autophagy protein ATG9A enables lipid mobilization from lipid droplets
E Mailler, CM Guardia, X Bai, M Jarnik, CD Williamson, Y Li, N Maio, ...
Nature Communications 12 (1), 6750, 2021
662021
α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes
A Dilsizoglu Senol, M Samarani, S Syan, CM Guardia, T Nonaka, N Liv, ...
PLoS biology 19 (7), e3001287, 2021
622021
Structural basis of redox-dependent modulation of galectin-1 dynamics and function
CM Guardia, JJ Caramelo, M Trujillo, SP Méndez-Huergo, R Radi, ...
Glycobiology 24 (5), 428-441, 2014
612014
Mechanisms of polarized organelle distribution in neurons
DJ Britt, GG Farías, CM Guardia, JS Bonifacino
Frontiers in cellular neuroscience 10, 88, 2016
542016
Carbohydrate-binding proteins: Dissecting ligand structures through solvent environment occupancy
DF Gauto, S Di Lella, CMA Guardia, DA Estrin, MA Martí
The Journal of Physical Chemistry B 113 (25), 8717-8724, 2009
472009
SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum
A Saric, SA Freeman, CD Williamson, M Jarnik, CM Guardia, ...
Nature communications 12 (1), 4552, 2021
422021
Thiol redox biochemistry: insights from computer simulations
A Zeida, CM Guardia, P Lichtig, LL Perissinotti, LA Defelipe, A Turjanski, ...
Biophysical reviews 6, 27-46, 2014
362014
Bivalent motif-ear interactions mediate the association of the accessory protein tepsin with the AP-4 adaptor complex
R Mattera, CM Guardia, SS Sidhu, JS Bonifacino
Journal of Biological Chemistry 290 (52), 30736-30749, 2015
312015
An integrated computational analysis of the structure, dynamics, and ligand binding interactions of the human galectin network
CMA Guardia, DF Gauto, S Di Lella, GA Rabinovich, MA Martí, DA Estrin
Journal of chemical information and modeling 51 (8), 1918-1930, 2011
312011
Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning
CM Guardia, R De Pace, A Sen, A Saric, M Jarnik, DA Kolin, A Kunwar, ...
PLoS biology 17 (5), e3000279, 2019
242019
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