R. John MacLeod
R. John MacLeod
Associate Professor, Queen's University
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Extracellular calcium sensing and extracellular calcium signaling
EM Brown, RJ MacLeod
Physiological reviews 81 (1), 239-297, 2001
Regulation of MAP kinase by calcium-sensing receptor in bovine parathyroid and CaR-transfected HEK293 cells
O Kifor, RJ MacLeod, R Diaz, M Bai, T Yamaguchi, T Yao, I Kifor, ...
American Journal of Physiology-Renal Physiology 280 (2), F291-F302, 2001
Filamin-A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase
G Hjälm, RJ MacLeod, O Kifor, N Chattopadhyay, EM Brown
Journal of Biological Chemistry 276 (37), 34880-34887, 2001
Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells
RJ MacLeod, M Hayes, I Pacheco
American Journal of Physiology-Gastrointestinal and Liver Physiology 293 (1 …, 2007
Stimulation of human neutrophils by 5-oxo-6, 8, 11, 14-eicosatetraenoic acid by a mechanism independent of the leukotriene B4 receptor
WS Powell, S Gravel, RJ MacLeod, E Mills, M Hashefi
Journal of Biological Chemistry 268 (13), 9280-9286, 1993
Calcium-sensing receptor stimulates PTHrP release by pathways dependent on PKC, p38 MAPK, JNK, and ERK1/2 in H-500 cells
J Tfelt-Hansen, RJ MacLeod, N Chattopadhyay, S Yano, S Quinn, X Ren, ...
American Journal of Physiology-Endocrinology and Metabolism 285 (2), E329-E337, 2003
Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in prostate cancer cells: role of epidermal growth factor receptor transactivation
S Yano, RJ Macleod, N Chattopadhyay, J Tfelt-Hansen, O Kifor, ...
Bone 35 (3), 664-672, 2004
Cl-secretion in a model intestinal epithelium induced by a neutrophil-derived secretagogue.
JL Madara, C Parkos, S Colgan, RJ MacLeod, S Nash, J Matthews, ...
The Journal of clinical investigation 89 (6), 1938-1944, 1992
FGF9-induced proliferative response to eosinophilic inflammation in oesophagitis
DJ Mulder, I Pacheco, DJ Hurlbut, N Mak, GT Furuta, RJ MacLeod, ...
Gut 58 (2), 166-173, 2009
PTHrP stimulated by the calcium-sensing receptor requires MAP kinase activation
RJ MacLeod, N Chattopadhyay, EM Brown
American Journal of Physiology-Endocrinology and Metabolism 284 (2), E435-E442, 2003
Cftr modulates Wnt/β-catenin signaling and stem cell proliferation in murine intestine
AM Strubberg, J Liu, NM Walker, CD Stefanski, RJ MacLeod, ST Magness, ...
Cellular and molecular gastroenterology and hepatology 5 (3), 253-271, 2018
CaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epithelia
II Pacheco, RJ MacLeod
American Journal of Physiology-Gastrointestinal and Liver Physiology 295 (4 …, 2008
Metabolism and biologic effects of 5-oxoeicosanoids on human neutrophils.
WS Powell, RJ MacLeod, S Gravel, F Gravelle, A Bhakar
Journal of immunology (Baltimore, Md.: 1950) 156 (1), 336-342, 1996
The extracellular calcium-sensing receptor reciprocally regulates the secretion of BMP-2 and the BMP antagonist Noggin in colonic myofibroblasts
D Peiris, I Pacheco, C Spencer, RJ MacLeod
American Journal of Physiology-Gastrointestinal and Liver Physiology 292 (3 …, 2007
Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism
RJ MacLeod, S Yano, N Chattopadhyay, EM Brown
Biochemical and biophysical research communications 320 (2), 455-460, 2004
Characterization of the inhibitory effect of boiled rice on intestinal chloride secretion in guinea pig crypt cells
CJ Mathews, RJ MacLeod, SX Zheng, JW Hanrahan, HPJ Bennett, ...
Gastroenterology 116 (6), 1342-1347, 1999
Corticostatic peptides cause nifedipine-sensitive volume reduction in jejunal villus enterocytes.
RJ MacLeod, JR Hamilton, A Bateman, D Belcourt, J Hu, HP Bennett, ...
Proceedings of the National Academy of Sciences 88 (2), 552-556, 1991
Volume regulation initiated by Na (+)-nutrient cotransport in isolated mammalian villus enterocytes
RJ MAcLEOD, JR Hamilton
American Journal of Physiology-Gastrointestinal and Liver Physiology 260 (1 …, 1991
The Isolation and Characterization of a Novel Corticostatin/Defensin-like Peptide from the Kidney (∗)
A Bateman, RJ MacLeod, P Lembessis, J Hu, F Esch, S Solomon
Journal of Biological Chemistry 271 (18), 10654-10659, 1996
Regulatory volume increase in mammalian jejunal villus cells is due to bumetanide-sensitive NaKCl2 cotransport
RJ MAcLEOD, JR Hamilton
American Journal of Physiology-Gastrointestinal and Liver Physiology 258 (5 …, 1990
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