Hay RT
Hay RT
Professor of Molecular Biology, University of Dundee
Patvirtintas el. paštas
SUMO: a history of modification
RT Hay
Molecular cell 18 (1), 1-12, 2005
SUMO-1 modification of IκBα inhibits NF-κB activation
JMP Desterro, MS Rodriguez, RT Hay
Molecular cell 2 (2), 233-239, 1998
Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62
JR Matthews, N Wakasugi, JL Virelizier, J Yodoi, RT Hay
Nucleic acids research 20 (15), 3821-3830, 1992
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
MH Tatham, E Jaffray, OA Vaughan, JMP Desterro, CH Botting, ...
Journal of Biological Chemistry 276 (38), 35368-35374, 2001
SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting
MS Rodriguez, C Dargemont, RT Hay
Journal of Biological Chemistry 276 (16), 12654-12659, 2001
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
MH Tatham, MC Geoffroy, L Shen, A Plechanovova, N Hattersley, ...
Nature cell biology 10 (5), 538-546, 2008
SUMO‐1 modification activates the transcriptional response of p53
MS Rodriguez, JMP Desterro, S Lain, CA Midgley, DP Lane, RT Hay
The EMBO journal, 1999
Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
DP Xirodimas, MK Saville, JC Bourdon, RT Hay, DP Lane
Cell 118 (1), 83-97, 2004
Nuclear localization of IκBα promotes active transport of NF-κB from the nucleus to the cytoplasm
F Arenzana-Seisdedos, P Turpin, M Rodriguez, D Thomas, RT Hay, ...
Journal of cell science 110 (3), 369-378, 1997
Inducible nuclear expression of newly synthesized IκBα negatively regulates DNA-binding and transcriptional activities of NF-κB
F Arenzana-Seisdedos, J Thompson, MS Rodriguez, F Bachelerie, ...
Molecular and cellular biology 15 (5), 2689-2696, 1995
Inhibition of NF-κB DNA binding by nitric oxide
JR Matthews, CH Botting, M Panico, HR Morris, RT Hay
Nucleic acids research 24 (12), 2236-2242, 1996
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
A Plechanovová, EG Jaffray, MH Tatham, JH Naismith, RT Hay
Nature 489 (7414), 115-120, 2012
System-wide changes to SUMO modifications in response to heat shock
F Golebiowski, I Matic, MH Tatham, C Cole, Y Yin, A Nakamura, J Cox, ...
Science signaling 2 (72), ra24-ra24, 2009
P300 transcriptional repression is mediated by SUMO modification
D Girdwood, D Bumpass, OA Vaughan, A Thain, LA Anderson, ...
Molecular cell 11 (4), 1043-1054, 2003
Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation
MS Rodriguez, JMP Desterro, S Lain, DP Lane, RT Hay
Molecular and cellular biology 20 (22), 8458-8467, 2000
Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1
JMP Desterro, MS Rodriguez, GD Kemp, RT Hay
Journal of Biological Chemistry 274 (15), 10618-10624, 1999
Family-wide analysis of poly (ADP-ribose) polymerase activity
S Vyas, I Matic, L Uchima, J Rood, R Zaja, RT Hay, I Ahel, P Chang
Nature communications 5 (1), 4426, 2014
Ubch9 conjugates SUMO but not ubiquitin
JMP Desterro, J Thomson, RT Hay
FEBS letters 417 (3), 297-300, 1997
Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IκBα
E Cabannes, G Khan, F Aillet, RF Jarrett, RT Hay
Oncogene 18 (20), 3063-3070, 1999
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
T Bouras, M Fu, AA Sauve, F Wang, AA Quong, ND Perkins, RT Hay, ...
Journal of Biological Chemistry 280 (11), 10264-10276, 2005
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