Harmine inhibits tumour specific neo-vessel formation by regulating VEGF, MMP, TIMP and pro-inflammatory mediators both in vivo and in vitro TP Hamsa, G Kuttan European journal of pharmacology 649 (1-3), 64-73, 2010 | 151 | 2010 |
Antiangiogenic activity of berberine is mediated through the downregulation of hypoxia-inducible factor-1, VEGF, and proinflammatory mediators TP Hamsa, G Kuttan Drug and Chemical Toxicology 35 (1), 57-70, 2012 | 107 | 2012 |
Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma TP Hamsa, G Kuttan Chinese Medicine 6, 1-8, 2011 | 106 | 2011 |
Tinospora cordifolia ameliorates urotoxic effect of cyclophosphamide by modulating GSH and cytokine levels TP Hamsa, G Kuttan Experimental and toxicologic Pathology 64 (4), 307-314, 2012 | 60 | 2012 |
Effect of Thuja occidentalis and its polysaccharide on cell-mediated immune responses and cytokine levels of metastatic tumor-bearing animals ES Sunila, TP Hamsa, G Kuttan Pharmaceutical biology 49 (10), 1065-1073, 2011 | 54 | 2011 |
Berberine inhibits pulmonary metastasis through down‐regulation of MMP in metastatic B16F‐10 melanoma cells TP Hamsa, G Kuttan Phytotherapy Research 26 (4), 568-578, 2012 | 49 | 2012 |
Induction of apoptosis by sulforaphane in highly metastatic B16F-10 melanoma cells TP Hamsa, P Thejass, G Kuttan Drug and chemical toxicology 34 (3), 332-340, 2011 | 48 | 2011 |
Protective role of Ipomoea obscura (L.) on cyclophosphamide-induced uro- and nephrotoxicities by modulating antioxidant status and pro-inflammatory cytokine … TP Hamsa, G Kuttan Inflammopharmacology 19, 155-167, 2011 | 45 | 2011 |
Evaluation of the Anti-inflammatory and Anti-tumor Effect of Ipomoea obscura (L) and Its Mode of Action Through the Inhibition of Pro Inflammatory Cytokines, Nitric … TP Hamsa, G Kuttan Inflammation 34, 171-183, 2011 | 40 | 2011 |
Maintenance of androgen receptor inactivation by S-nitrosylation Y Qin, A Dey, HT Purayil, Y Daaka Cancer research 73 (22), 6690-6699, 2013 | 28 | 2013 |
βArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility X Ma, L Espana-Serrano, W Kim, HT Purayil, Z Nie, Y Daaka Journal of Biological Chemistry 289 (19), 13638-13650, 2014 | 26 | 2014 |
Studies on anti-metastatic and anti-invasive effects of harmine using highly metastatic murine B16F-10 melanoma cells TP Hamsa, G Kuttan Journal of Environmental Pathology, Toxicology and Oncology 30 (2), 2011 | 26 | 2011 |
Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis Y Zhang, HT Purayil, JB Black, F Fetto, LD Lynch, JN Masannat, Y Daaka Cancer letters 391, 50-58, 2017 | 23 | 2017 |
βArrestin2 mediates renal cell carcinoma tumor growth J Masannat, HT Purayil, Y Zhang, M Russin, I Mahmud, W Kim, D Liao, ... Scientific reports 8 (1), 4879, 2018 | 22 | 2018 |
Arrestin2 modulates androgen receptor activation HT Purayil, Y Zhang, A Dey, Z Gersey, L Espana-Serrano, Y Daaka Oncogene 34 (24), 3144-3151, 2015 | 22 | 2015 |
Ipomoea obscura ameliorates cyclophosphamide-induced toxicity by modulating the immune system and levels of proinflammatory cytokine and GSH TP Hamsa, G Kuttan Canadian journal of physiology and pharmacology 88 (11), 1042-1053, 2010 | 21 | 2010 |
Ipomoea obscura (L.) enhances the functions of immunological effector cells, inhibits proinflammatory cytokines and nitric oxide production by LPS induced … TP Hamsa, G Kuttan Immunopharmacology and Immunotoxicology 31 (2), 222-229, 2009 | 12 | 2009 |
Inhibition of invasion and experimental metastasis of murine melanoma cells by Ipomoea obscura (L.) is mediated through the down-regulation of inflammatory mediators and matrix … TP Hamsa, G Kuttan Journal of experimental therapeutics & oncology 9 (2), 2011 | 11 | 2011 |
Ipobscurine, an indole alkaloid from Ipomoea obscura, inhibits tumor cell invasion and experimental metastasis by inducing apoptosis TP Hamsa, G Kuttan Journal of Environmental Pathology, Toxicology and Oncology 30 (2), 2011 | 9 | 2011 |
Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth A Mukhopadhyay, LE Hanold, H Thayele Purayil, SA Gisemba, ... Cancer Biology & Therapy 18 (8), 571-583, 2017 | 8 | 2017 |