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Xiang Yu
Xiang Yu
OLDP/OPQ/CDER/FDA
Verified email at fda.hhs.gov
Title
Cited by
Cited by
Year
Tanshinones inhibit amyloid aggregation by amyloid-β peptide, disaggregate amyloid fibrils, and protect cultured cells
Q Wang, X Yu, K Patal, R Hu, S Chuang, G Zhang, J Zheng
ACS chemical neuroscience 4 (6), 1004-1015, 2013
2212013
Cholesterol promotes the interaction of Alzheimer β-amyloid monomer with lipid bilayer
X Yu, J Zheng
Journal of molecular biology 421 (4-5), 561-571, 2012
1362012
Inhibition of amyloid-β aggregation in Alzheimer's disease
Q Wang, X Yu, L Li, J Zheng
Current pharmaceutical design 20 (8), 1223-1243, 2014
1132014
Comparative molecular dynamics study of human islet amyloid polypeptide (IAPP) and rat IAPP oligomers
G Liang, J Zhao, X Yu, J Zheng
Biochemistry 52 (6), 1089-1100, 2013
952013
Structure, orientation, and surface interaction of Alzheimer amyloid-β peptides on the graphite
X Yu, Q Wang, Y Lin, J Zhao, C Zhao, J Zheng
Langmuir 28 (16), 6595-6605, 2012
832012
Conformational basis for asymmetric seeding barrier in filaments of three-and four-repeat tau
A Siddiqua, Y Luo, V Meyer, MA Swanson, X Yu, G Wei, J Zheng, ...
Journal of the American Chemical Society 134 (24), 10271-10278, 2012
812012
Cross-seeding and conformational selection between three-and four-repeat human Tau proteins
X Yu, Y Luo, P Dinkel, J Zheng, G Wei, M Margittai, R Nussinov, B Ma
Journal of Biological Chemistry 287 (18), 14950-14959, 2012
752012
Tabersonine Inhibits Amyloid Fibril Formation and Cytotoxicity of Aβ (1–42)
T Kai, L Zhang, X Wang, A Jing, B Zhao, X Yu, J Zheng, F Zhou
ACS Chemical Neuroscience 6 (6), 879-888, 2015
672015
Polymorphic structures of Alzheimer's β-amyloid globulomers
X Yu, J Zheng
PloS one 6 (6), e20575, 2011
672011
Probing ion channel activity of human islet amyloid polypeptide (amylin)
J Zhao, Y Luo, H Jang, X Yu, G Wei, R Nussinov, J Zheng
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (12), 3121-3130, 2012
662012
Structural polymorphism of human islet amyloid polypeptide (hIAPP) oligomers highlights the importance of interfacial residue interactions
J Zhao, X Yu, G Liang, J Zheng
Biomacromolecules 12 (1), 210-220, 2011
632011
Molecular interactions of Alzheimer amyloid-β oligomers with neutral and negatively charged lipid bilayers
X Yu, Q Wang, Q Pan, F Zhou, J Zheng
Physical Chemistry Chemical Physics 15 (23), 8878-8889, 2013
622013
De novo design of self-assembled hexapeptides as β-amyloid (Aβ) peptide inhibitors
Q Wang, G Liang, M Zhang, J Zhao, K Patel, X Yu, C Zhao, B Ding, ...
ACS chemical neuroscience 5 (10), 972-981, 2014
552014
Single mutations in tau modulate the populations of fibril conformers through seed selection
V Meyer, PD Dinkel, Y Luo, X Yu, G Wei, J Zheng, GR Eaton, B Ma, ...
Angewandte Chemie 126 (6), 1616-1619, 2014
552014
Alzheimer Aβ1−42 Monomer Adsorbed on the Self-Assembled Monolayers
Q Wang, J Zhao, X Yu, C Zhao, L Li, J Zheng
Langmuir 26 (15), 12722-12732, 2010
512010
Comparative molecular dynamics study of Aβ adsorption on the self-assembled monolayers
Q Wang, C Zhao, J Zhao, J Wang, JC Yang, X Yu, J Zheng
Langmuir 26 (5), 3308-3316, 2010
492010
Molecular insights into the reversible formation of tau protein fibrils
Y Luo, P Dinkel, X Yu, M Margittai, J Zheng, R Nussinov, G Wei, B Ma
Chemical communications 49 (34), 3582-3584, 2013
482013
Heterogeneous triangular structures of human islet amyloid polypeptide (amylin) with internal hydrophobic cavity and external wrapping morphology reveal the polymorphic nature …
J Zhao, X Yu, G Liang, J Zheng
Biomacromolecules 12 (5), 1781-1794, 2011
402011
Rapid determination of Paeoniae Radix using near infrared spectroscopy
X Luo, X Yu, X Wu, Y Cheng, H Qu
Microchemical Journal 90 (1), 8-12, 2008
402008
Molecular modeling of two distinct triangular oligomers in amyloid β-protein
J Zheng, X Yu, J Wang, JC Yang, Q Wang
The journal of physical chemistry B 114 (1), 463-470, 2010
362010
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Articles 1–20