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Helen S. Toogood
Helen S. Toogood
Verified email at manchester.ac.uk
Title
Cited by
Cited by
Year
Biocatalytic reductions and chemical versatility of the old yellow enzyme family of flavoprotein oxidoreductases
HS Toogood, JM Gardiner, NS Scrutton
ChemCatChem 2 (8), 892-914, 2010
3082010
Discovery, characterization, engineering, and applications of ene-reductases for industrial biocatalysis
HS Toogood, NS Scrutton
ACS catalysis 8 (4), 3532-3549, 2018
1992018
New developments in ‘ene’-reductase catalysed biological hydrogenations
HS Toogood, NS Scrutton
Current opinion in chemical biology 19, 107-115, 2014
1512014
Calcium-mediated thermostability in the subtilisin superfamily: the crystal structure of Bacillus Ak. 1 protease at 1.8 ┼ resolution
CA Smith, HS Toogood, HM Baker, RM Daniel, EN Baker
Journal of molecular biology 294 (4), 1027-1040, 1999
1421999
Asymmetric reduction of activated alkenes by pentaerythritol tetranitrate reductase: specificity and control of stereochemical outcome by reaction optimisation
A Fryszkowska, H Toogood, M Sakuma, JM Gardiner, GM Stephens, ...
Advanced synthesis & catalysis 351 (17), 2976-2990, 2009
1302009
Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme
AJ Warman, O Roitel, R Neeli, HM Girvan, HE Seward, SA Murray, ...
Biochemical Society Transactions 33 (4), 747-753, 2005
1282005
Biocatalysis with thermostable enzymes: structure and properties of a thermophilic ‘ene’‐reductase related to old yellow enzyme
BV Adalbj÷rnsson, HS Toogood, A Fryszkowska, CR Pudney, TA Jowitt, ...
ChemBioChem 11 (2), 197-207, 2010
1272010
Dynamics driving function− new insights from electron transferring flavoproteins and partner complexes
HS Toogood, D Leys, NS Scrutton
The FEBS journal 274 (21), 5481-5504, 2007
1272007
Extensive domain motion and electron transfer in the human electron transferring flavoproteinĚ medium chain Acyl-CoA dehydrogenase complex
HS Toogood, A Van Thiel, J Basran, MJ Sutcliffe, NS Scrutton, D Leys
Journal of Biological Chemistry 279 (31), 32904-32912, 2004
1012004
Structure‐based insight into the asymmetric bioreduction of the C C double bond of α, β‐unsaturated nitroalkenes by pentaerythritol tetranitrate reductase
HS Toogood, A Fryszkowska, V Hare, K Fisher, A Roujeinikova, D Leys, ...
Advanced synthesis & catalysis 350 (17), 2789-2803, 2008
992008
Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli
AJ Jervis, P Carbonell, M Vinaixa, MS Dunstan, KA Hollywood, ...
ACS synthetic biology 8 (1), 127-136, 2018
872018
Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets: new heme ligation states influence conformational equilibria iná…
HM Girvan, HE Seward, HS Toogood, MR Cheesman, D Leys, AW Munro
Journal of Biological Chemistry 282 (1), 564-572, 2007
862007
Cysteine activation is an inherent in vitro property of prolyl-tRNA synthetases
I Ahel, C Stathopoulos, A Ambrogelly, A Sauerwald, H Toogood, ...
Journal of Biological Chemistry 277 (38), 34743-34748, 2002
852002
Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli
HS Toogood, AN Cheallaigh, S Tait, DJ Mansell, A Jervis, A Lygidakis, ...
ACS Synthetic Biology 4 (10), 1112-1123, 2015
802015
A site‐saturated mutagenesis study of pentaerythritol tetranitrate reductase reveals that residues 181 and 184 influence ligand binding, stereochemistry and reactivity
HS Toogood, A Fryszkowska, M Hulley, M Sakuma, D Mansell, ...
ChemBioChem 12 (5), 738-749, 2011
762011
Low carbon strategies for sustainable bio-alkane gas production and renewable energy
M Amer, EZ Wojcik, C Sun, R Hoeven, JMX Hughes, M Faulkner, ...
Energy & Environmental Science 13 (6), 1818-1831, 2020
742020
The use of a thermostable signature amidase in the resolution of the bicyclic synthon (rac)-γ-lactam
HS Toogood, RC Brown, K Line, PA Keene, SJC Taylor, R McCague, ...
Tetrahedron 60 (3), 711-716, 2004
692004
Focused directed evolution of pentaerythritol tetranitrate reductase by using automated anaerobic kinetic screening of site‐saturated libraries
ME Hulley, HS Toogood, A Fryszkowska, D Mansell, GM Stephens, ...
ChemBioChem 11 (17), 2433-2447, 2010
662010
Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase from Nicotiana tabacum
DJ Mansell, HS Toogood, J Waller, JMX Hughes, CW Levy, JM Gardiner, ...
ACS catalysis 3 (3), 370-379, 2013
632013
A thermostable L-aminoacylase from Thermococcus litoralis: cloning, overexpression, characterization, and applications in biotransformations
HS Toogood, EJ Hollingsworth, RC Brown, IN Taylor, SJ Taylor, ...
Extremophiles 6, 111-122, 2002
552002
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Articles 1–20