Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome S Schoenfelder, R Sugar, A Dimond, BM Javierre, H Armstrong, B Mifsud, ... Nature genetics 47 (10), 1179-1186, 2015 | 395 | 2015 |
Modeling the evolution of ETV6-RUNX1–induced B-cell precursor acute lymphoblastic leukemia in mice L van der Weyden, G Giotopoulos, AG Rust, LS Matheson, FW van Delft, ... Blood 118 (4), 1041-1051, 2011 | 105 | 2011 |
H-Chain-only antibodies M Brüggemann, X Zou, L Matheson, M Osborn US Patent App. 12/455,913, 2010 | 77 | 2010 |
Two mutually exclusive local chromatin states drive efficient V (D) J recombination DJ Bolland, H Koohy, AL Wood, LS Matheson, F Krueger, ... Cell reports 15 (11), 2475-2487, 2016 | 70 | 2016 |
Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells H Koohy, DJ Bolland, LS Matheson, S Schoenfelder, C Stellato, A Dimond, ... Genome biology 19 (1), 1-24, 2018 | 41 | 2018 |
Removal of the BiP-retention domain in Cμ permits surface deposition and developmental progression without L-chain X Zou, JA Smith, D Corcos, LS Matheson, MJ Osborn, M Brüggemann Molecular immunology 45 (13), 3573-3579, 2008 | 37 | 2008 |
The timing of differentiation and potency of CD8 effector function is set by RNA binding proteins G Petkau, TJ Mitchell, K Chakraborty, SE Bell, L Matheson, DJ Turner, ... Nature communications 13 (1), 1-16, 2022 | 36 | 2022 |
Polypyrimidine tract-binding proteins are essential for B cell development E Monzón-Casanova, LS Matheson, K Tabbada, K Zarnack, CWJ Smith, ... Elife 9, e53557, 2020 | 36 | 2020 |
Diverse human VH antibody fragments with bio-therapeutic properties from the Crescendo Mouse Y Teng, JL Young, B Edwards, P Hayes, L Thompson, C Johnston, ... New biotechnology 55, 65-76, 2020 | 33 | 2020 |
B-cell receptors and heavy chain diseases: guilty by association? D Corcos, MJ Osborn, LS Matheson Blood 117 (26), 6991-6998, 2011 | 32 | 2011 |
Immunoglobulin aggregation leading to Russell body formation is prevented by the antibody light chain D Corcos, MJ Osborn, LS Matheson, F Santos, X Zou, JA Smith, G Morgan, ... Blood, The Journal of the American Society of Hematology 115 (2), 282-288, 2010 | 31 | 2010 |
Local chromatin features including PU. 1 and IKAROS binding and H3K4 methylation shape the repertoire of immunoglobulin kappa genes chosen for V (D) J recombination LS Matheson, DJ Bolland, P Chovanec, F Krueger, S Andrews, H Koohy, ... Frontiers in immunology 8, 1550, 2017 | 28 | 2017 |
Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ LMC Webb, S Fra‐Bido, S Innocentin, LS Matheson, N Attaf, A Bignon, ... Aging cell 20 (1), e13295, 2021 | 27 | 2021 |
Unbiased quantification of immunoglobulin diversity at the DNA level with VDJ-seq P Chovanec, DJ Bolland, LS Matheson, AL Wood, F Krueger, S Andrews, ... Nature protocols 13 (6), 1232-1252, 2018 | 24 | 2018 |
Local and global epigenetic regulation of V (D) J recombination LS Matheson, AE Corcoran Epigenetic Regulation of Lymphocyte Development, 65-89, 2011 | 16 | 2011 |
ORFLine: a bioinformatic pipeline to prioritize small open reading frames identifies candidate secreted small proteins from lymphocytes F Hu, J Lu, LS Matheson, MD Díaz-Muńoz, A Saveliev, J Xu, M Turner Bioinformatics 37 (19), 3152-3159, 2021 | 14 | 2021 |
Clonally stable Vκ allelic choice instructs Igκ repertoire R Levin-Klein, S Fraenkel, M Lichtenstein, LS Matheson, O Bartok, ... Nature communications 8 (1), 1-10, 2017 | 13 | 2017 |
Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell LS Matheson, G Petkau, B Sáenz-Narciso, V D’Angeli, J McHugh, ... Scientific Reports 12 (1), 1-24, 2022 | 10 | 2022 |
Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells V D'Angeli, E Monzón‐Casanova, LS Matheson, Ö Gizlenci, G Petkau, ... European Journal of Immunology, 2022 | 8 | 2022 |
A functional screen of RNA binding proteins identifies genes that promote or limit the accumulation of CD138+ plasma cells DJ Turner, A Saveliev, F Salerno, LS Matheson, M Screen, H Lawson, ... Elife 11, e72313, 2022 | 8 | 2022 |