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Katie Paul Friedman
Katie Paul Friedman
Toxicologist, National Center for Computational Toxicology, Office of Research and Development, U.S
Verified email at epa.gov - Homepage
Title
Cited by
Cited by
Year
Short-term in vivo exposure to the water contaminant triclosan: evidence for disruption of thyroxine
KM Crofton, KB Paul, MJ DeVito, JM Hedge
Environmental toxicology and pharmacology 24 (2), 194-197, 2007
2862007
The next generation blueprint of computational toxicology at the US Environmental Protection Agency
RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ...
Toxicological Sciences 169 (2), 317-332, 2019
1842019
Short-term Exposure to Triclosan Decreases Thyroxine In Vivo via Upregulation of Hepatic Catabolism in Young Long-Evans Rats
KB Paul, JM Hedge, MJ DeVito, KM Crofton
Toxicological Sciences 113 (2), 367-379, 2010
1422010
Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: a dynamic and kinetic evaluation of a putative mode-of-action
KB Paul, JM Hedge, R Bansal, RT Zoeller, R Peter, MJ DeVito, ...
Toxicology 300 (1-2), 31-45, 2012
1232012
Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization
K Paul Friedman, M Gagne, LH Loo, P Karamertzanis, T Netzeva, ...
Toxicological Sciences 173 (1), 202-225, 2020
982020
Tiered high-throughput screening approach to identify thyroperoxidase inhibitors within the ToxCast phase I and II chemical libraries
K Paul Friedman, ED Watt, MW Hornung, JM Hedge, RS Judson, ...
Toxicological Sciences 151 (1), 160-180, 2016
912016
Developmental triclosan exposure decreases maternal and neonatal thyroxine in rats
KB Paul, JM Hedge, MJ DeVito, KM Crofton
Environmental Toxicology and Chemistry 29 (12), 2840-2844, 2010
912010
Development of a thyroperoxidase inhibition assay for high-throughput screening
KB Paul, JM Hedge, DM Rotroff, MW Hornung, KM Crofton, SO Simmons
Chemical research in toxicology 27 (3), 387-399, 2014
792014
In Vitro Perturbations of Targets in Cancer Hallmark Processes Predict Rodent Chemical Carcinogenesis
NC Kleinstreuer, DJ Dix, KA Houck, RJ Kavlock, TB Knudsen, MT Martin, ...
toxicological sciences 131 (1), 40-55, 2013
792013
Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches
PD Noyes, KP Friedman, P Browne, JT Haselman, ME Gilbert, ...
Environmental health perspectives 127 (9), 095001, 2019
712019
Evidence for triclosan-induced activation of human and rodent xenobiotic nuclear receptors
KB Paul, JT Thompson, SO Simmons, JPV Heuvel, KM Crofton
Toxicology in vitro 27 (7), 2049-2060, 2013
532013
ToxRefDB version 2.0: Improved utility for predictive and retrospective toxicology analyses
S Watford, LL Pham, J Wignall, R Shin, MT Martin, KP Friedman
Reproductive Toxicology 89, 145-158, 2019
502019
Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling
J Nyffeler, C Willis, R Lougee, A Richard, K Paul-Friedman, JA Harrill
Toxicology and applied pharmacology 389, 114876, 2020
472020
An exposure: activity profiling method for interpreting high-throughput screening data for estrogenic activity—Proof of concept
RA Becker, KP Friedman, TW Simon, MS Marty, G Patlewicz, ...
Regulatory Toxicology and Pharmacology 71 (3), 398-408, 2015
462015
Limited chemical structural diversity found to modulate thyroid hormone receptor in the Tox21 chemical library
K Paul-Friedman, M Martin, KM Crofton, CW Hsu, S Sakamuru, J Zhao, ...
Environmental health perspectives 127 (9), 097009, 2019
452019
Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat
KB Paul, JM Hedge, C Macherla, DL Filer, E Burgess, SO Simmons, ...
Toxicology 312, 97-107, 2013
392013
High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects on steroidogenesis
DE Haggard, AL Karmaus, MT Martin, RS Judson, RW Setzer, ...
Toxicological Sciences 162 (2), 509-534, 2018
332018
Variability in in vivo studies: Defining the upper limit of performance for predictions of systemic effect levels
LL Pham, SM Watford, P Pradeep, MT Martin, RS Thomas, RS Judson, ...
Computational Toxicology 15, 100126, 2020
262020
A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study
K Paul Friedman, S Papineni, MS Marty, KD Yi, AK Goetz, RJ Rasoulpour, ...
Critical Reviews in Toxicology 46 (9), 785-833, 2016
262016
Evaluation of chemical effects on network formation in cortical neurons grown on microelectrode arrays
TJ Shafer, JP Brown, B Lynch, S Davila-Montero, K Wallace, KP Friedman
Toxicological Sciences 169 (2), 436-455, 2019
252019
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