| Dietary methionine influences therapy in mouse cancer models and alters human metabolism X Gao, SM Sanderson, Z Dai, MA Reid, DE Cooper, M Lu, JP Richie Jr, ... Nature 572 (7769), 397-401, 2019 | 485 | 2019 |
| The impact of cellular metabolism on chromatin dynamics and epigenetics MA Reid, Z Dai, JW Locasale Nature cell biology 19 (11), 1298-1306, 2017 | 429 | 2017 |
| Methionine metabolism in health and cancer: a nexus of diet and precision medicine SM Sanderson, X Gao, Z Dai, JW Locasale Nature Reviews Cancer 19 (11), 625-637, 2019 | 349 | 2019 |
| Metabolic landscape of the tumor microenvironment at single cell resolution Z Xiao, Z Dai, JW Locasale Nature communications 10 (1), 3763, 2019 | 344 | 2019 |
| Deep learning for drug-induced liver injury Y Xu, Z Dai, F Chen, S Gao, J Pei, L Lai Journal of chemical information and modeling 55 (10), 2085-2093, 2015 | 329 | 2015 |
| The evolving metabolic landscape of chromatin biology and epigenetics Z Dai, V Ramesh, JW Locasale Nature Reviews Genetics 21 (12), 737-753, 2020 | 292 | 2020 |
| A predictive model for selective targeting of the Warburg effect through GAPDH inhibition with a natural product MV Liberti, Z Dai, SE Wardell, JA Baccile, X Liu, X Gao, R Baldi, ... Cell metabolism 26 (4), 648-659. e8, 2017 | 193 | 2017 |
| Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism MA Reid, AE Allen, S Liu, MV Liberti, P Liu, X Liu, Z Dai, X Gao, Q Wang, ... Nature communications 9 (1), 5442, 2018 | 166 | 2018 |
| Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open … J Guinney, T Wang, TD Laajala, KK Winner, JC Bare, EC Neto, SA Khan, ... The Lancet Oncology 18 (1), 132-142, 2017 | 161 | 2017 |
| Prediction of human population responses to toxic compounds by a collaborative competition F Eduati, LM Mangravite, T Wang, H Tang, JC Bare, R Huang, T Norman, ... Nature biotechnology 33 (9), 933-940, 2015 | 119 | 2015 |
| Methionine metabolism influences genomic architecture and gene expression through H3K4me3 peak width Z Dai, SJ Mentch, X Gao, SN Nichenametla, JW Locasale Nature communications 9 (1), 1955, 2018 | 111 | 2018 |
| Understanding metabolism with flux analysis: From theory to application Z Dai, JW Locasale Metabolic engineering 43, 94-102, 2017 | 97 | 2017 |
| Discovery of novel 15-lipoxygenase activators to shift the human arachidonic acid metabolic network toward inflammation resolution H Meng, CL McClendon, Z Dai, K Li, X Zhang, S He, E Shang, Y Liu, L Lai Journal of Medicinal Chemistry 59 (9), 4202-4209, 2016 | 55 | 2016 |
| Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer KH Lin, JC Rutter, A Xie, B Pardieu, ET Winn, RD Bello, A Forget, ... Nature genetics 52 (4), 408-417, 2020 | 54 | 2020 |
| A flux balance of glucose metabolism clarifies the requirements of the Warburg effect Z Dai, AA Shestov, L Lai, JW Locasale Biophysical journal 111 (5), 1088-1100, 2016 | 49 | 2016 |
| Quantitative analysis of the physiological contributions of glucose to the TCA cycle S Liu, Z Dai, DE Cooper, DG Kirsch, JW Locasale Cell metabolism 32 (4), 619-628. e21, 2020 | 42 | 2020 |
| Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification I Hwang, H Uchida, Z Dai, F Li, T Sanchez, JW Locasale, LC Cantley, ... Nature communications 12 (1), 640, 2021 | 28 | 2021 |
| Nutrient availability shapes methionine metabolism in p16/MTAP-deleted cells SM Sanderson, PG Mikhael, V Ramesh, Z Dai, JW Locasale Science advances 5 (6), eaav7769, 2019 | 27 | 2019 |
| Dynamic 13C flux analysis captures the reorganization of adipocyte glucose metabolism in response to insulin LE Quek, JR Krycer, S Ohno, K Yugi, DJ Fazakerley, R Scalzo, ... Iscience 23 (2), 2020 | 26 | 2020 |
| Molecular mechanism of 15-lipoxygenase allosteric activation and inhibition H Meng, Z Dai, W Zhang, Y Liu, L Lai Physical Chemistry Chemical Physics 20 (21), 14785-14795, 2018 | 25 | 2018 |
Jason LocasaleDuke UniversityVerified email at alum.mit.edu
