Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ... Science 334 (6061), 1372-1377, 2011 | 383 | 2011 |
Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum NMB Brancucci, JP Gerdt, CQ Wang, M De Niz, N Philip, SR Adapa, ... Cell 171 (7), 1532-1544. e15, 2017 | 327 | 2017 |
Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families SER Bopp, MJ Manary, AT Bright, GL Johnston, NV Dharia, FL Luna, ... PLoS genetics 9 (2), e1003293, 2013 | 254 | 2013 |
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ... Science 359 (6372), 191-199, 2018 | 244 | 2018 |
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum NV Dharia, ABS Sidhu, MB Cassera, SJ Westenberger, SER Bopp, ... Genome biology 10, 1-13, 2009 | 166 | 2009 |
Mutations in Plasmodium falciparum actin-binding protein coronin confer reduced artemisinin susceptibility AR Demas, AI Sharma, W Wong, AM Early, S Redmond, S Bopp, ... Proceedings of the National Academy of Sciences 115 (50), 12799-12804, 2018 | 160 | 2018 |
Validation of isoleucine utilization targets in Plasmodium falciparum ES Istvan, NV Dharia, SE Bopp, I Gluzman, EA Winzeler, DE Goldberg Proceedings of the National Academy of Sciences 108 (4), 1627-1632, 2011 | 156 | 2011 |
Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia A Mukherjee, S Bopp, P Magistrado, W Wong, R Daniels, A Demas, ... Malaria journal 16, 1-12, 2017 | 141 | 2017 |
Identification of nuclear proteins that interact differentially with Plasmodium falciparum var gene promoters TS Voss, M Kaestli, D Vogel, S Bopp, HP Beck Molecular microbiology 48 (6), 1593-1607, 2003 | 135 | 2003 |
Plasmepsin II–III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum S Bopp, P Magistrado, W Wong, SF Schaffner, A Mukherjee, P Lim, ... Nature communications 9 (1), 1769, 2018 | 131 | 2018 |
Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio) diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G … KC Nicolaou, M Lu, S Totokotsopoulos, P Heretsch, D Giguere, YP Sun, ... Journal of the American Chemical Society 134 (41), 17320-17332, 2012 | 130 | 2012 |
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs JD Herman, LR Pepper, JF Cortese, G Estiu, K Galinsky, V Zuzarte-Luis, ... Science translational medicine 7 (288), 288ra77-288ra77, 2015 | 109 | 2015 |
A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor T Nam, CW McNamara, S Bopp, NV Dharia, S Meister, GMC Bonamy, ... ACS chemical biology 6 (11), 1214-1222, 2011 | 109 | 2011 |
Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites NV Dharia, D Plouffe, SER Bopp, GE González-Páez, C Lucas, C Salas, ... Genome research 20 (11), 1534-1544, 2010 | 76 | 2010 |
CRISPR‐Cas9‐modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine‐containing compounds but … CL Ng, G Siciliano, MCS Lee, MJ de Almeida, VC Corey, SE Bopp, ... Molecular microbiology 101 (3), 381-393, 2016 | 71 | 2016 |
Identification of pathogen genomic variants through an integrated pipeline MJ Manary, SS Singhakul, EL Flannery, SER Bopp, VC Corey, AT Bright, ... BMC bioinformatics 15, 1-14, 2014 | 61 | 2014 |
Cyclic nucleotide-specific phosphodiesterases of Plasmodium falciparum: PfPDEα, a non-essential cGMP-specific PDE that is an integral membrane protein L Wentzinger, S Bopp, H Tenor, J Klar, R Brun, HP Beck, T Seebeck International journal for parasitology 38 (14), 1625-1637, 2008 | 56 | 2008 |
Genome wide analysis of inbred mouse lines identifies a locus containing ppar-γ as contributing to enhanced malaria survival SER Bopp, V Ramachandran, K Henson, A Luzader, M Lindstrom, ... PLoS One 5 (5), e10903, 2010 | 37 | 2010 |
Plasmodium falciparum Gametocyte Density and Infectivity in Peripheral Blood and Skin Tissue of Naturally Infected Parasite Carriers in Burkina Faso E Meibalan, A Barry, MP Gibbins, S Awandu, L Meerstein-Kessel, ... The Journal of Infectious Diseases 223 (10), 1822-1830, 2021 | 23 | 2021 |
Genetic background and PfKelch13 affect artemisinin susceptibility of PfCoronin mutants in Plasmodium falciparum AI Sharma, SH Shin, S Bopp, SK Volkman, DL Hartl, DF Wirth PLoS Genetics 16 (12), e1009266, 2020 | 22 | 2020 |