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Evan Brower
Evan Brower
Director, NextCure Inc.
Verified email at nextcure.com
Title
Cited by
Cited by
Year
Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120
N Madani, A Schön, AM Princiotto, JM LaLonde, JR Courter, T Soeta, ...
Structure 16 (11), 1689-1701, 2008
2052008
Inhibition of HIV‐2 protease by HIV‐1 protease inhibitors in clinical use
ET Brower, UM Bacha, Y Kawasaki, E Freire
Chemical biology & drug design 71 (4), 298-305, 2008
1232008
Structural basis of nSH2 regulation and lipid binding in PI3Kα
MS Miller, O Schmidt-Kittler, DM Bolduc, ET Brower, D Chaves-Moreira, ...
Oncotarget 5 (14), 5198, 2014
782014
Blue ferrocenium azurin: An organometalloprotein with tunable redox properties
HJ Hwang, JR Carey, ET Brower, AJ Gengenbach, JA Abramite, Y Lu
Journal of the American Chemical Society 127 (44), 15356-15357, 2005
572005
Activation of PI3Kα by physiological effectors and by oncogenic mutations: structural and dynamic effects
SB Gabelli, I Echeverria, M Alexander, KC Duong-Ly, D Chaves-Moreira, ...
Biophysical reviews 6, 89-95, 2014
382014
Binding thermodynamics of the N-terminal peptide of the CCR5 coreceptor to HIV-1 envelope glycoprotein gp120
ET Brower, A Schon, JC Klein, E Freire
Biochemistry 48 (4), 779-785, 2009
352009
Naturally occurring variability in the envelope glycoprotein of HIV-1 and development of cell entry inhibitors
ET Brower, A Schön, E Freire
Biochemistry 49 (11), 2359-2367, 2010
202010
Design and synthesis of novel metalloproteins through reversible encapsulation of metal complexes by proteins.
JR Carey, SK Ma, E Brower, Y Lu
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 222, U566-U566, 2001
142001
Capitalizing on tumor genotyping: towards the design of mutation specific inhibitors of phosphoinsitide-3-kinase
SB Gabelli, KC Duong-Ly, ET Brower, LM Amzel
Advances in enzyme regulation 51 (1), 273-279, 2011
52011
Smith 3RD, AB, Sodroski, J., 2008
N Madani, A Schon, AM Princiotto, JM Lalonde, JR Courter, T Soeta, D Ng, ...
Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 …, 0
3
The PI3K Pathway in Colorectal Cancers
J Yun, G Poulogiannis, ET Brower, S Klempner, LL Cantley
Molecular Pathogenesis of Colorectal Cancer, 157-199, 2013
22013
Use of transient transfection for cGMP manufacturing of eOD-GT8 60mer, a self-assembling nanoparticle germline-targeting HIV-1 vaccine candidate
VK Sharma, V Tsvetnitsky, S Menis, ET Brower, E Sayeed, J Ackland, ...
bioRxiv, 2022.09. 30.510310, 2022
12022
The molecular architecture of p85α as determined by SAXS and chemical cross-linking.
ET Brower, SB Gabelli, Q Wang, R Chaerkady, CE Berndsen, RN Cole, ...
Cancer Research 73 (8_Supplement), 2225-2225, 2013
12013
Engineering of metalloproteins and novel biocatalysts using native protein scaffolds
JR Carey, SM Berry, TD Pfister, H Kim, X Zhao, HJ Hwang, NY Wang, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 225, U30-U30, 2003
12003
Targeting PI3K: The PIP2 binding site
M Miller, O Schmidt-Kittler, DM Bolduc, ET Brower, D Chaves-Moreira, ...
MOLECULAR CANCER THERAPEUTICS 14 (7), 2015
2015
Abstract PR02: Targeting PI3K: The PIP2 binding site
M Miller, O Schmidt-Kittler, DM Bolduc, ET Brower, D Chaves-Moreira, ...
Molecular Cancer Therapeutics 14 (7_Supplement), PR02-PR02, 2015
2015
Abstract LB-326: Structural basis of lipid-binding and regulation in PI3Kα
MS Miller, O Schmidt-Kittler, DM Bolduc, ET Brower, D Chaves-Moreira, ...
Cancer Research 74 (19_Supplement), LB-326-LB-326, 2014
2014
Creation and Optimization of Novel Semisynthetic Metalloproteins
ET Brower
University of Illinois at Urbana-Champaign, 2003
2003
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