Identification and characterization of a missense mutation in the O-linked β-N-acetylglucosamine (O-GlcNAc) transferase gene that segregates with X-linked intellectual disability K Vaidyanathan, T Niranjan, N Selvan, CF Teo, M May, S Patel, ... Journal of Biological Chemistry 292 (21), 8948-8963, 2017 | 103 | 2017 |
Predicting protein–DNA binding free energy change upon missense mutations using modified MM/PBSA approach: SAMPDI webserver Y Peng, L Sun, Z Jia, L Li, E Alexov Bioinformatics 34 (5), 779-786, 2018 | 72 | 2018 |
Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails Y Peng, S Li, A Onufriev, D Landsman, AR Panchenko Nature communications 12 (1), 5280, 2021 | 64 | 2021 |
DelPhi suite: new developments and review of functionalities C Li, Z Jia, A Chakravorty, S Pahari, Y Peng, S Basu, M Koirala, ... Journal of computational chemistry 40 (28), 2502-2508, 2019 | 54 | 2019 |
Investigating the linkage between disease‐causing amino acid variants and their effect on protein stability and binding Y Peng, E Alexov Proteins: Structure, Function, and Bioinformatics 84 (2), 232-239, 2016 | 53 | 2016 |
DNA methylation: Precise modulation of chromatin structure and dynamics S Li, Y Peng, AR Panchenko Current opinion in structural biology 75, 102430, 2022 | 51 | 2022 |
Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy YR Lee, K Khan, K Armfield-Uhas, S Srikanth, NA Thompson, M Pardo, ... Nature communications 11 (1), 3698, 2020 | 50 | 2020 |
DelPhiForce web server: electrostatic forces and energy calculations and visualization L Li, Z Jia, Y Peng, A Chakravorty, L Sun, E Alexov Bioinformatics 33 (22), 3661-3663, 2017 | 46 | 2017 |
Histone tails as signaling antennas of chromatin Y Peng, S Li, D Landsman, AR Panchenko Current opinion in structural biology 67, 153-160, 2021 | 37 | 2021 |
Forces and Disease: Electrostatic force differences caused by mutations in kinesin motor domains can distinguish between disease-causing and non-disease-causing mutations L Li, Z Jia, Y Peng, S Godar, I Getov, S Teng, J Alper, E Alexov Scientific reports 7 (1), 8237, 2017 | 36 | 2017 |
DNA methylation cues in nucleosome geometry, stability, and unwrapping S Li, Y Peng, D Landsman, A Panchenko Biophysical Journal 121 (3), 524a, 2022 | 32 | 2022 |
Revealing the effects of missense mutations causing Snyder-Robinson syndrome on the stability and dimerization of spermine synthase Y Peng, J Norris, C Schwartz, E Alexov International journal of molecular sciences 17 (1), 77, 2016 | 32 | 2016 |
Gaussian-based smooth dielectric function: a surface-free approach for modeling macromolecular binding in solvents A Chakravorty, Z Jia, Y Peng, N Tajielyato, L Wang, E Alexov Frontiers in molecular biosciences 5, 25, 2018 | 26 | 2018 |
Computational investigation of proton transfer, pKa shifts and pH-optimum of protein-DNA and protein-RNA complexes Y Peng, E Alexov Biophysical Journal 112 (3), 518a, 2017 | 25 | 2017 |
Key apoptotic genes APAF1 and CASP9 implicated in recurrent folate-resistant neural tube defects CJ Spellicy, J Norris, R Bend, C Bupp, P Mester, T Reynolds, J Dean, ... European Journal of Human Genetics 26 (3), 420-427, 2018 | 24 | 2018 |
Pharmacogenetics of human sulfotransferases and impact of amino acid exchange on Phase II drug metabolism A Isvoran, Y Peng, S Ceauranu, L Schmidt, AB Nicot, MA Miteva Drug Discovery Today 27 (11), 103349, 2022 | 23 | 2022 |
Structural perspective on revealing and altering molecular functions of genetic variants linked with diseases Y Peng, E Alexov, S Basu International journal of molecular sciences 20 (3), 548, 2019 | 23 | 2019 |
Computational Investigation of the Missense Mutations in DHCR7 Gene Associated with Smith-Lemli-Opitz Syndrome Y Peng, R Myers, W Zhang, E Alexov International Journal of Molecular Sciences 19 (1), 141, 2018 | 23 | 2018 |
Mutations in the KDM5C ARID domain and their plausible association with syndromic Claes-Jensen-Type disease Y Peng, J Suryadi, Y Yang, TG Kucukkal, W Cao, E Alexov International Journal of Molecular Sciences 16 (11), 27270-27287, 2015 | 23 | 2015 |
E-hooks provide guidance and a soft landing for the microtubule binding domain of dynein N Tajielyato, L Li, Y Peng, J Alper, E Alexov Scientific reports 8 (1), 13266, 2018 | 22 | 2018 |