| Neurotoxic reactive astrocytes are induced by activated microglia SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, ... Nature 541 (7638), 481-487, 2017 | 6147 | 2017 |
| Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease SP Yun, TI Kam, N Panicker, SM Kim, Y Oh, JS Park, SH Kwon, YJ Park, ... Nature medicine 24 (7), 931-938, 2018 | 860 | 2018 |
| Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson’s disease I Martin, JW Kim, BD Lee, HC Kang, JC Xu, H Jia, J Stankowski, MS Kim, ... Cell 157 (2), 472-485, 2014 | 301 | 2014 |
| Activation of tyrosine kinase c-Abl contributes to α-synuclein–induced neurodegeneration S Brahmachari, P Ge, SH Lee, D Kim, SS Karuppagounder, M Kumar, ... The Journal of clinical investigation 126 (8), 2970-2988, 2016 | 165 | 2016 |
| Toward the human cellular microRNAome MN McCall, MS Kim, M Adil, AH Patil, Y Lu, CJ Mitchell, P Leal-Rojas, ... Genome research 27 (10), 1769-1781, 2017 | 151 | 2017 |
| Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson’s disease N Panicker, TI Kam, H Wang, S Neifert, SC Chou, M Kumar, ... Neuron 110 (15), 2422-2437. e9, 2022 | 84 | 2022 |
| LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-mediated neurotoxicity SS Karuppagounder, Y Xiong, Y Lee, MC Lawless, D Kim, E Nordquist, ... Journal of chemical neuroanatomy 76, 90-97, 2016 | 54 | 2016 |
| Defects in mitochondrial biogenesis drive mitochondrial alterations in PARKIN-deficient human dopamine neurons M Kumar, J Acevedo-Cintrón, A Jhaldiyal, H Wang, SA Andrabi, S Eacker, ... Stem Cell Reports 15 (3), 629-645, 2020 | 51 | 2020 |
| Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson’s disease S Brahmachari, S Lee, S Kim, C Yuan, SS Karuppagounder, P Ge, R Shi, ... Brain 142 (8), 2380-2401, 2019 | 49 | 2019 |
| Defects in mRNA translation in LRRK2-mutant hiPSC-derived dopaminergic neurons lead to dysregulated calcium homeostasis JW Kim, X Yin, A Jhaldiyal, MR Khan, I Martin, Z Xie, T Perez-Rosello, ... Cell stem cell 27 (4), 633-645. e7, 2020 | 41 | 2020 |
| PARIS farnesylation prevents neurodegeneration in models of Parkinson’s disease A Jo, Y Lee, TI Kam, SU Kang, S Neifert, SS Karuppagounder, R Khang, ... Science translational medicine 13 (604), eaax8891, 2021 | 39 | 2021 |
| Dymeclin deficiency causes postnatal microcephaly, hypomyelination and reticulum-to-Golgi trafficking defects in mice and humans N Dupuis, A Fafouri, A Bayot, M Kumar, T Lecharpentier, G Ball, ... Human molecular genetics 24 (10), 2771-2783, 2015 | 34 | 2015 |
| Optimized derivation and functional characterization of 5-HT neurons from human embryonic stem cells M Kumar, SK Kaushalya, P Gressens, S Maiti, S Mani Stem cells and development 18 (4), 615-628, 2009 | 33 | 2009 |
| A Novel RAB33B Mutation in Smith–McCort Dysplasia N Dupuis, S Lebon, M Kumar, S Drunat, LM Graul‐Neumann, P Gressens, ... Human mutation 34 (2), 283-286, 2013 | 32 | 2013 |
| Conditional induction of Math1 specifies embryonic stem cells to cerebellar granule neuron lineage and promotes differentiation into mature granule neurons R Srivastava, M Kumar, S Peineau, Z Csaba, S Mani, P Gressens, ... Stem cells 31 (4), 652-665, 2013 | 24 | 2013 |
| Neurospheres derived from human embryoid bodies treated with retinoic Acid show an increase in nestin and ngn2 expression that correlates with the proportion of tyrosine … M Kumar, B Bagchi, SK Gupta, AS Meena, P Gressens, S Mani Stem cells and development 16 (4), 667-682, 2007 | 22 | 2007 |
| CMV promotor activity during ES cell differentiation: potential insight into embryonic stem cell differentiation B Bagchi, M Kumar, S Mani Cell biology international 30 (6), 505-513, 2006 | 21 | 2006 |
| Endogenous cerebellar neurogenesis in adult mice with progressive ataxia M Kumar, Z Csaba, S Peineau, R Srivastava, S Rasika, S Mani, ... Annals of Clinical and Translational Neurology 1 (12), 968-981, 2014 | 18 | 2014 |
| Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson’s disease SK Pirooznia, H Wang, N Panicker, M Kumar, S Neifert, MA Dar, E Lau, ... Science Advances 8 (13), eabh1824, 2022 | 11 | 2022 |
| The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson’s disease SS Karuppagounder, H Wang, T Kelly, R Rush, R Nguyen, S Bisen, ... Science translational medicine 15 (679), eabp9352, 2023 | 9 | 2023 |
