Jason S. McLellan
Jason S. McLellan
Professor of Molecular Biosciences
Verified email at - Homepage
Cited by
Cited by
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
D Wrapp, N Wang, KS Corbett, JA Goldsmith, CL Hsieh, O Abiona, ...
Science 367 (6483), 1260-1263, 2020
Site-specific glycan analysis of the SARS-CoV-2 spike
Y Watanabe, JD Allen, D Wrapp, JS McLellan, M Crispin
Science 369 (6501), 330-333, 2020
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness
KS Corbett, DK Edwards, SR Leist, OM Abiona, S Boyoglu-Barnum, ...
Nature 586 (7830), 567-571, 2020
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
J Pallesen, N Wang, KS Corbett, D Wrapp, RN Kirchdoerfer, HL Turner, ...
Proceedings of the National Academy of Sciences 114 (35), E7348-E7357, 2017
Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
CL Hsieh, JA Goldsmith, JM Schaub, AM DiVenere, HC Kuo, ...
Science 369 (6510), 1501-1505, 2020
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ...
Nature 480 (7377), 336-343, 2011
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus
JS McLellan, M Chen, MG Joyce, M Sastry, GBE Stewart-Jones, Y Yang, ...
science 342 (6158), 592-598, 2013
Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody
JS McLellan, M Chen, S Leung, KW Graepel, X Du, Y Yang, T Zhou, ...
Science 340 (6136), 1113-1117, 2013
Pre-fusion structure of a human coronavirus spike protein
RN Kirchdoerfer, CA Cottrell, N Wang, J Pallesen, HM Yassine, HL Turner, ...
Nature 531 (7592), 118-121, 2016
Beyond shielding: the roles of glycans in the SARS-CoV-2 spike protein
L Casalino, Z Gaieb, JA Goldsmith, CK Hjorth, AC Dommer, AM Harbison, ...
ACS central science 6 (10), 1722-1734, 2020
Immunogenicity of a DNA vaccine candidate for COVID-19
TRF Smith, A Patel, S Ramos, D Elwood, X Zhu, J Yan, EN Gary, ...
Nature communications 11 (1), 2601, 2020
Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies
D Wrapp, D De Vlieger, KS Corbett, GM Torres, N Wang, W Van Breedam, ...
Cell 181 (5), 1004-1015. e15, 2020
Broad neutralization of SARS-related viruses by human monoclonal antibodies
AZ Wec, D Wrapp, AS Herbert, DP Maurer, D Haslwanter, M Sakharkar, ...
Science 369 (6504), 731-736, 2020
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
RN Kirchdoerfer, N Wang, J Pallesen, D Wrapp, HL Turner, CA Cottrell, ...
Scientific reports 8 (1), 15701, 2018
Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2
M Rolland, PT Edlefsen, BB Larsen, S Tovanabutra, E Sanders-Buell, ...
Nature 490 (7420), 417-420, 2012
Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes
JS McLellan, Y Yang, BS Graham, PD Kwong
Journal of virology 85 (15), 7788-7796, 2011
Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2
HX Liao, M Bonsignori, SM Alam, JS McLellan, GD Tomaras, MA Moody, ...
Immunity 38 (1), 176-186, 2013
The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates
NI Mazur, D Higgins, MC Nunes, JA Melero, AC Langedijk, N Horsley, ...
The Lancet Infectious Diseases 18 (10), e295-e311, 2018
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates
BE Jones, PL Brown-Augsburger, KS Corbett, K Westendorf, J Davies, ...
Science translational medicine 13 (593), eabf1906, 2021
Prefusion F–specific antibodies determine the magnitude of RSV neutralizing activity in human sera
JO Ngwuta, M Chen, K Modjarrad, MG Joyce, M Kanekiyo, A Kumar, ...
Science translational medicine 7 (309), 309ra162-309ra162, 2015
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