Lydia Aschauer
Lydia Aschauer
Orbit Discovery
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Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress
A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ...
Journal of proteomics 79, 180-194, 2013
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics
A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ...
Toxicology in Vitro 30 (1), 117-127, 2015
Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes
A Limonciel, L Aschauer, A Wilmes, S Prajczer, MO Leonard, W Pfaller, ...
Toxicology in Vitro 25 (8), 1855-1862, 2011
Expression of xenobiotic transporters in the human renal proximal tubule cell line RPTEC/TERT1
L Aschauer, G Carta, N Vogelsang, E Schlatter, P Jennings
Toxicology in Vitro 30 (1), 95-105, 2015
Delineation of the key aspects in the regulation of epithelial monolayer formation
L Aschauer, LN Gruber, W Pfaller, A Limonciel, TJ Athersuch, R Cavill, ...
Molecular and cellular biology 33 (13), 2535-2550, 2013
Novel targets and interaction partners of mutant p53 Gain-Of-Function
L Aschauer, PAJ Muller
Biochemical Society Transactions 44 (2), 460-466, 2016
Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: a transcriptomic study
L Aschauer, A Limonciel, A Wilmes, S Stanzel, A Kopp-Schneider, ...
Toxicology in Vitro 30 (1), 106-116, 2015
Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model
P Jennings, C Weiland, A Limonciel, KM Bloch, R Radford, L Aschauer, ...
Archives of toxicology 86, 571-589, 2012
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells
A Limonciel, A Wilmes, L Aschauer, R Radford, KM Bloch, T McMorrow, ...
Archives of toxicology 86, 1741-1751, 2012
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing
D Crean, P Bellwon, L Aschauer, A Limonciel, K Moenks, P Hewitt, ...
Toxicology in Vitro 30 (1), 128-137, 2015
Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing
A Limonciel, K Moenks, S Stanzel, GL Truisi, C Parmentier, L Aschauer, ...
Toxicology in Vitro 30 (1), 7-18, 2015
Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel
A Wilmes, L Aschauer, A Limonciel, W Pfaller, P Jennings
Toxicology and applied pharmacology 279 (2), 163-172, 2014
Interleukin-19 as a translational indicator of renal injury
P Jennings, D Crean, L Aschauer, A Limonciel, K Moenks, G Kern, ...
Archives of toxicology 89, 101-106, 2015
Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane
V Phatak, Y von Grabowiecki, J Janus, L Officer, C Behan, L Aschauer, ...
Cell Death & Disease 12 (2), 207, 2021
Persistence of epigenomic effects after recovery from repeated treatment with two nephrocarcinogens
A Limonciel, SG Van Breda, X Jiang, GD Tredwell, A Wilmes, L Aschauer, ...
Frontiers in Genetics 9, 558, 2018
Transcriptomic alterations induced by Monuron in rat and human renal proximal tubule cells in vitro and comparison to rat renal-cortex in vivo
KM Bloch, N Yaqoob, S Sharma, A Evans, L Aschauer, R Radford, ...
Toxicology Research 4 (2), 423-431, 2015
Renal cell culture
P Jennings, L Aschauer, A Wilmes, G Gstraunthaler
In Vitro Toxicology Systems, 79-101, 2014
Application of a human renal proximal tubule cell line, RPTEC/TERT1, for chemical safety assessment
L Aschauer, A Wilmes, A Limonciel, MO Leonard, W Pfaller, P Jennings
Toxicology Letters, S242-S243, 2014
Rab11-FIP1/RCP functions as a major signalling hub in the oncogenic roles of mutant p53 in cancer
Y von Grabowiecki, V Phatak, L Aschauer, PAJ Muller
Frontiers in Oncology 11, 5457, 2021
Toxicity profiling of nephrotoxins in the human proximal tubular RPTEC-TERT1 cell line: influence of hypoxia
D Crean, L Aschauer, P Jennings, M Leonard
Altex 27 (suppl 2/10), 31, 2010
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