Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors S Dallavalle, V Dobričić, L Lazzarato, E Gazzano, M Machuqueiro, ... Drug Resistance Updates 50, 100682, 2020 | 201 | 2020 |
The role of the European Chemicals Bureau in promoting the regulatory use of (Q) SAR methods AP Worth, A Bassan, J De Bruijn, A Gallegos Saliner, T Netzeva, M Pavan, ... SAR and QSAR in Environmental Research 18 (1-2), 111-125, 2007 | 169 | 2007 |
Computational studies of free radical-scavenging properties of phenolic compounds P Alov, I Tsakovska, I Pajeva Current topics in medicinal chemistry 15 (2), 85-104, 2015 | 119 | 2015 |
Quantitative structure-skin permeability relationships I Tsakovska, I Pajeva, M Al Sharif, P Alov, E Fioravanzo, S Kovarich, ... Toxicology 387, 27-42, 2017 | 104 | 2017 |
The characterisation of (quantitative) structure-activity relationships: preliminary guidance AP Worth, A Bassan, A Gallegos, TI Netzeva, G Patlewicz, M Pavan, ... Institute for Health and Consumer Protection, Toxicology and Chemical …, 2005 | 99 | 2005 |
Mechanistic QSAR of aromatic amines: new models for discriminating between homocyclic mutagens and nonmutagens, and validation of models for carcinogens R Benigni, C Bossa, T Netzeva, A Rodomonte, I Tsakovska Environmental and Molecular Mutagenesis 48 (9), 754-771, 2007 | 95 | 2007 |
Interactions of poly (vinylpyrrolidone) with ibuprofen and naproxen: experimental and modeling studies S Bogdanova, I Pajeva, P Nikolova, I Tsakovska, B Müller Pharmaceutical research 22, 806-815, 2005 | 89 | 2005 |
Repurposing old drugs to fight multidrug resistant cancers J Dinić, T Efferth, AT García-Sosa, J Grahovac, JM Padrón, I Pajeva, ... Drug Resistance Updates 52, 100713, 2020 | 72 | 2020 |
A mini review of mammalian toxicity (Q) SAR models I Tsakovska, I Lessigiarska, T Netzeva, AP Worth QSAR & Combinatorial Science 27 (1), 41-48, 2008 | 63 | 2008 |
Validation of counter propagation neural network models for predictive toxicology according to the OECD principles: a case study M Vračko, V Bandelj, P Barbieri, E Benfenati, Q Chaudhry, M Cronin, ... SAR and QSAR in Environmental Research 17 (3), 265-284, 2006 | 54 | 2006 |
Molecular modelling study of the PPARγ receptor in relation to the mode of action/adverse outcome pathway framework for liver steatosis I Tsakovska, M Al Sharif, P Alov, A Diukendjieva, E Fioravanzo, ... International Journal of Molecular Sciences 15 (5), 7651-7666, 2014 | 43 | 2014 |
QSAR and 3D-QSAR of phenothiazine type multidrug resistance modulators in P388/ADR cells IM Tsakovska Bioorganic & medicinal chemistry 11 (13), 2889-2899, 2003 | 38 | 2003 |
Evaluation of SARs for the prediction of skin irritation/corrosion potential–structural inclusion rules in the BfR decision support system A Gallegos Saliner, I Tsakovska, M Pavan, G Patlewicz, AP Worth SAR and QSAR in Environmental Research 18 (3-4), 331-342, 2007 | 30 | 2007 |
Modes-of-action related to repeated dose toxicity: Tissue-specific biological roles of PPARγ ligand-dependent dysregulation in nonalcoholic fatty liver disease M Al Sharif, P Alov, V Vitcheva, I Pajeva, I Tsakovska PPAR research 2014, 2014 | 29 | 2014 |
Cytotoxicity and microbicidal activity of commonly used organic solvents: A comparative study and application to a standardized extract from Vaccinium macrocarpon Y Ilieva, L Dimitrova, MM Zaharieva, M Kaleva, P Alov, I Tsakovska, ... Toxics 9 (5), 92, 2021 | 27 | 2021 |
Phenothiazines and structurally related compounds as modulators of cancer multidrug resistance I Tsakovska, I Pajeva Current Drug Targets 7 (9), 1123-1134, 2006 | 27 | 2006 |
The application of molecular modelling in the safety assessment of chemicals: A case study on ligand-dependent PPARγ dysregulation M Al Sharif, I Tsakovska, I Pajeva, P Alov, E Fioravanzo, A Bassan, ... Toxicology 392, 140-154, 2017 | 26 | 2017 |
Evaluation of SARs for the prediction of eye irritation/corrosion potential–structural inclusion rules in the BfR decision support system I Tsakovska, AG Saliner, T Netzeva, M Pavan, AP Worth SAR and QSAR in Environmental Research 18 (3-4), 221-235, 2007 | 25 | 2007 |
Novel heat shock protein 90 inhibitors suppress P-glycoprotein activity and overcome multidrug resistance in cancer cells J Dinić, A Podolski-Renić, M Jovanović, L Musso, I Tsakovska, I Pajeva, ... International Journal of Molecular Sciences 20 (18), 4575, 2019 | 24 | 2019 |
In vitro and in silico studies of the membrane permeability of natural flavonoids from Silybum marianum (L.) Gaertn. and their derivatives A Diukendjieva, P Alov, I Tsakovska, T Pencheva, A Richarz, V Kren, ... Phytomedicine 53, 79-85, 2019 | 22 | 2019 |