Zi-Fu Wang
Zi-Fu Wang
Harvard Medical School
Verified email at
Cited by
Cited by
An open-source drug discovery platform enables ultra-large virtual screens
C Gorgulla, A Boeszoermenyi, ZF Wang, PD Fischer, PW Coote, ...
Nature 580 (7805), 663-668, 2020
Direct evidence of mitochondrial G-quadruplex DNA by using fluorescent anti-cancer agents
WC Huang, TY Tseng, YT Chen, CC Chang, ZF Wang, CL Wang, TN Hsu, ...
Nucleic acids research 43 (21), 10102-10113, 2015
NIN-like protein 7 transcription factor is a plant nitrate sensor
KH Liu, M Liu, Z Lin, ZF Wang, B Chen, C Liu, A Guo, M Konishi, ...
Science 377 (6613), 1419-1425, 2022
The hairpin form of r (G4C2) exp in c9ALS/FTD is repeat-associated non-ATG translated and a target for bioactive small molecules
ZF Wang, A Ursu, JL Childs-Disney, R Guertler, WY Yang, V Bernat, ...
Cell chemical biology 26 (2), 179-190. e12, 2019
Cryo-EM structure of an activated GPCR–G protein complex in lipid nanodiscs
M Zhang, M Gui, ZF Wang, C Gorgulla, JJ Yu, H Wu, ZJ Sun, C Klenk, ...
Nature structural & molecular biology 28 (3), 258-267, 2021
Approved anti-cancer drugs target oncogenic non-coding RNAs
SP Velagapudi, MG Costales, BR Vummidi, Y Nakai, AJ Angelbello, ...
Cell Chemical Biology 25 (9), 1086-1094. e7, 2018
Using genome sequence to enable the design of medicines and chemical probes
AJ Angelbello, JL Chen, JL Childs-Disney, P Zhang, ZF Wang, MD Disney
Chemical reviews 118 (4), 1599-1663, 2018
Structural basis of sodium–potassium exchange of a human telomeric DNA quadruplex without topological conversion
ZF Wang, MH Li, STD Hsu, TC Chang
Nucleic acids research 42 (7), 4723-4733, 2014
A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening
C Gorgulla, KMP Das, KE Leigh, M Cespugli, PD Fischer, ZF Wang, ...
Iscience 24 (2), 2021
Conformational Transition of a Hairpin Structure to G-Quadruplex within the WNT1 Gene Promoter
MHJ Kuo, ZF Wang, TY Tseng, MH Li, STD Hsu, JJ Lin, TC Chang
Journal of the American Chemical Society 137 (1), 210-218, 2015
In-cell optical imaging of exogenous G-quadruplex DNA by fluorogenic ligands
TY Tseng, ZF Wang, CH Chien, TC Chang
Nucleic acids research 41 (22), 10605-10618, 2013
Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizers
JM Wang, FC Huang, MHJ Kuo, ZF Wang, TY Tseng, LC Chang, SJ Yen, ...
Journal of Biological Chemistry 289 (21), 14612-14623, 2014
A massively parallel selection of small molecule-RNA motif binding partners informs design of an antiviral from sequence
JL Childs-Disney, T Tran, BR Vummidi, SP Velagapudi, HS Haniff, ...
Chem 4 (10), 2384-2404, 2018
Expression of the human telomerase reverse transcriptase gene is modulated by quadruplex formation in its first exon due to DNA methylation
PT Li, ZF Wang, YM Kuan, MH Li, MC Huang, PC Chiang, TC Chang, ...
Journal of Biological Chemistry 292 (51), 20859-20870, 2017
Chemical principles for the design of a novel fluorescent probe with high cancer-targeting selectivity and sensitivity
CC Kang, WC Huang, CW Kouh, ZF Wang, CC Cho, CC Chang, CL Wang, ...
Integrative biology 5 (10), 1217-1228, 2013
Chemical modulation of DNA replication along G-quadruplex based on topology-dependent ligand binding
S Takahashi, A Kotar, H Tateishi-Karimata, S Bhowmik, ZF Wang, ...
Journal of the American Chemical Society 143 (40), 16458-16469, 2021
A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes
ZF Wang, MH Li, WW Chen, STD Hsu, TC Chang
Nucleic Acids Research 44 (8), 3958-3968, 2016
A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress
PC Wei, ZF Wang, WT Lo, MI Su, JY Shew, TC Chang, WH Lee
Nucleic acids research 41 (3), 1533-1543, 2013
Structural conversion of intramolecular and intermolecular G-quadruplexes of bcl2mid: the effect of potassium concentration and ion exchange
CT Lin, TY Tseng, ZF Wang, TC Chang
The Journal of Physical Chemistry B 115 (10), 2360-2370, 2011
Molecular engineering of G-quadruplex ligands based on solvent effect of polyethylene glycol
ZF Wang, TC Chang
Nucleic acids research 40 (17), 8711-8720, 2012
The system can't perform the operation now. Try again later.
Articles 1–20