Andres Binolfi
Andres Binolfi
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Structural disorder of monomeric α-synuclein persists in mammalian cells
FX Theillet, A Binolfi, B Bekei, A Martorana, HM Rose, M Stuiver, S Verzini, ...
Nature 530 (7588), 45-50, 2016
Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)
FX Theillet, A Binolfi, T Frembgen-Kesner, K Hingorani, M Sarkar, C Kyne, ...
Chemical reviews 114 (13), 6661-6714, 2014
Interaction of α-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement
A Binolfi, RM Rasia, CW Bertoncini, M Ceolin, M Zweckstetter, ...
Journal of the American Chemical Society 128 (30), 9893-9901, 2006
Thermodynamics of protein destabilization in live cells
J Danielsson, X Mu, L Lang, H Wang, A Binolfi, FX Theillet, B Bekei, ...
Proceedings of the National Academy of Sciences 112 (40), 12402-12407, 2015
Site-specific interactions of Cu (II) with α and β-synuclein: Bridging the molecular gap between metal binding and aggregation
A Binolfi, GR Lamberto, R Duran, L Quintanar, CW Bertoncini, JM Souza, ...
Journal of the American Chemical Society 130 (35), 11801-11812, 2008
Bacterial in-cell NMR of human α-synuclein: a disordered monomer by nature?
A Binolfi, FX Theillet, P Selenko
Biochemical Society Transactions 40 (5), 950-954, 2012
Bioinorganic chemistry of Parkinson’s disease: structural determinants for the copper-mediated amyloid formation of alpha-synuclein
A Binolfi, EE Rodriguez, D Valensin, N D’Amelio, E Ippoliti, G Obal, ...
Inorganic chemistry 49 (22), 10668-10679, 2010
Structural characterization of the intrinsically unfolded protein β-synuclein, a natural negative regulator of α-synuclein aggregation
CW Bertoncini, RM Rasia, GR Lamberto, A Binolfi, M Zweckstetter, ...
Journal of molecular biology 372 (3), 708-722, 2007
Bioinorganic chemistry of copper coordination to alpha-synuclein: relevance to Parkinson's disease
A Binolfi, L Quintanar, CW Bertoncini, C Griesinger, CO Fernández
Coordination Chemistry Reviews 256 (19-20), 2188-2201, 2012
Structural and mechanistic basis behind the inhibitory interaction of PcTS on α-synuclein amyloid fibril formation
GR Lamberto, A Binolfi, ML Orcellet, CW Bertoncini, M Zweckstetter, ...
Proceedings of the National Academy of Sciences 106 (50), 21057-21062, 2009
Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species
F González-Lizárraga, SB Socías, CL Ávila, CM Torres-Bugeau, ...
Scientific reports 7 (1), 1-13, 2017
Intracellular repair of oxidation-damaged α-synuclein fails to target C-terminal modification sites
A Binolfi, A Limatola, S Verzini, J Kosten, FX Theillet, H May Rose, ...
Nature communications 7 (1), 10251, 2016
Site-specific NMR mapping and time-resolved monitoring of serine and threonine phosphorylation in reconstituted kinase reactions and mammalian cell extracts
FX Theillet, HM Rose, S Liokatis, A Binolfi, R Thongwichian, M Stuiver, ...
Nature protocols 8 (7), 1416-1432, 2013
Site-specific copper-catalyzed oxidation of α-synuclein: Tightening the link between metal binding and protein oxidative damage in Parkinson’s disease
MC Miotto, EE Rodriguez, AA Valiente-Gabioud, V Torres-Monserrat, ...
Inorganic chemistry 53 (9), 4350-4358, 2014
Exploring the structural details of Cu (I) binding to α-synuclein by NMR spectroscopy
A Binolfi, AA Valiente-Gabioud, R Duran, M Zweckstetter, C Griesinger, ...
Journal of the American Chemical Society 133 (2), 194-196, 2011
Oral yeast carriage in HIV‐infected and non‐infected populations in Rosario, Argentina
AG Luque, MS Biasoli, ME Tosello, A Binolfi, S Lupo, HM Magaró
Mycoses 52 (1), 53-59, 2009
Copper binding to the N-terminally acetylated, naturally occurring form of alpha-synuclein induces local helical folding
MC Miotto, AA Valiente-Gabioud, G Rossetti, M Zweckstetter, P Carloni, ...
Journal of the American Chemical Society 137 (20), 6444-6447, 2015
Efficient modification of alpha-synuclein serine 129 by protein kinase CK1 requires phosphorylation of tyrosine 125 as a priming event
J Kosten, A Binolfi, M Stuiver, S Verzini, FX Theillet, B Bekei, ...
ACS chemical neuroscience 5 (12), 1203-1208, 2014
Real-time NMR monitoring of biological activities in complex physiological environments
MJ Smith, CB Marshall, FX Theillet, A Binolfi, P Selenko, M Ikura
Current opinion in structural biology 32, 39-47, 2015
Structural basis behind the interaction of Zn2+ with the protein α-synuclein and the Aβ peptide: A comparative analysis
AA Valiente-Gabioud, V Torres-Monserrat, L Molina-Rubino, A Binolfi, ...
Journal of inorganic biochemistry 117, 334-341, 2012
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