| Src kinase phosphorylates Caspase‐8 on Tyr380: a novel mechanism of apoptosis suppression S Cursi, A Rufini, V Stagni, I Conḍ, V Matafora, A Bachi, AP Bonifazi, ... The EMBO journal 25 (9), 1895-1905, 2006 | 228 | 2006 |
| GD3 ganglioside directly targets mitochondria in a bcl‐2‐controlled fashion MR Rippo, F Malisan, L Rayagnan, B Tomassini, I Condo, P Costantini, ... The FASEB Journal 14 (13), 2047-2054, 2000 | 220 | 2000 |
| In vivo maturation of human frataxin I Condo, N Ventura, F Malisan, A Rufini, B Tomassini, R Testi Human molecular genetics 16 (13), 1534-1540, 2007 | 140 | 2007 |
| Acetylation suppresses the proapoptotic activity of GD3 ganglioside F Malisan, L Franchi, B Tomassini, N Ventura, I Conḍ, MR Rippo, ... The Journal of experimental medicine 196 (12), 1535-1541, 2002 | 124 | 2002 |
| A pool of extramitochondrial frataxin that promotes cell survival I Condò, N Ventura, F Malisan, B Tomassini, R Testi Journal of Biological Chemistry 281 (24), 16750-16756, 2006 | 114 | 2006 |
| Cis‐acting signals controlling translational initiation in the thermophilic archaeon Sulfolobus solfataricus I Conḍ, A Ciammaruconi, D Benelli, D Ruggero, P Londei Molecular microbiology 34 (2), 377-384, 1999 | 102 | 1999 |
| Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans N Ventura, S Rea, ST Henderson, I Condo, TE Johnson, R Testi Aging cell 4 (2), 109-112, 2005 | 87 | 2005 |
| Caspase-dependent cleavage of c-Abl contributes to apoptosis D Barilà, A Rufini, I Conḍ, N Ventura, K Dorey, G Superti-Furga, R Testi Molecular and cellular biology 23 (8), 2790-2799, 2003 | 85 | 2003 |
| Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans A Schiavi, A Torgovnick, A Kell, E Megalou, N Castelein, I Guccini, ... Experimental gerontology 48 (2), 191-201, 2013 | 77 | 2013 |
| Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin I Condo, F Malisan, I Guccini, D Serio, A Rufini, R Testi Human molecular genetics 19 (7), 1221-1229, 2010 | 77 | 2010 |
| Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model B Tomassini, G Arcuri, S Fortuni, C Sandi, V Ezzatizadeh, C Casali, ... Human molecular genetics 21 (13), 2855-2861, 2012 | 75 | 2012 |
| Preventing the ubiquitin–proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia A Rufini, S Fortuni, G Arcuri, I Condo, D Serio, O Incani, F Malisan, ... Human molecular genetics 20 (7), 1253-1261, 2011 | 63 | 2011 |
| Frataxin participates to the hypoxia-induced response in tumors I Guccini, D Serio, I Condo, A Rufini, B Tomassini, A Mangiola, G Maira, ... Cell death & disease 2 (2), e123-e123, 2011 | 60 | 2011 |
| E3 ligase RNF126 directly ubiquitinates frataxin, promoting its degradation: identification of a potential therapeutic target for Friedreich ataxia M Benini, S Fortuni, I Conḍ, G Alfedi, F Malisan, N Toschi, D Serio, ... Cell reports 18 (8), 2007-2017, 2017 | 49 | 2017 |
| ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells V Stagni, MG di Bari, S Cursi, I Conḍ, MT Cencioni, R Testi, Y Lerenthal, ... Blood, The Journal of the American Society of Hematology 111 (2), 829-837, 2008 | 41 | 2008 |
| SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia C Bon, R Luffarelli, R Russo, S Fortuni, B Pierattini, C Santulli, C Fimiani, ... Nucleic Acids Research 47 (20), 10728-10743, 2019 | 40 | 2019 |
| A caspaselike activity is triggered by LPS and is required for survival of human dendritic cells L Franchi, I Condo, B Tomassini, C Nicolo, R Testi Blood 102 (8), 2910-2915, 2003 | 38 | 2003 |
| Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells A Rufini, F Cavallo, I Conḍ, S Fortuni, G De Martino, O Incani, ... Neurobiology of disease 75, 91-99, 2015 | 36 | 2015 |
| Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia G Alfedi, R Luffarelli, I Conḍ, G Pedini, L Mannucci, DS Massaro, ... Movement Disorders 34 (3), 323-334, 2019 | 33 | 2019 |
| A novel aminopeptidase associated with the 60 kDa chaperonin in the thermophilic archaeon Sulfolobus solfataricus I Condo, D Ruggero, R Reinhardt, P Londei Molecular microbiology 29 (3), 775-785, 1998 | 27 | 1998 |
